Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Hemoglobin Hakkari: an autosomal dominant form of beta thalassemia with inclusion bodies arising from de novo mutation in exon 2 of beta globin gene. 2010 Pediatr Blood Cancer
Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. 2010 Stroke
Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses. 2010 Proc Natl Acad Sci U S A
Characterization of axon guidance cue sensitivity of human embryonic stem cell-derived dopaminergic neurons. 2010 Mol Cell Neurosci
shRNA-mediated decreases in c-Met levels affect the differentiation potential of human mesenchymal stem cells and reduce their capacity for tissue repair. 2010 Tissue Eng Part A
Alternative control: what's WASp doing in the nucleus? 2010 Sci Transl Med
Nuclear reprogramming to a pluripotent state by three approaches. 2010 Nature
CD133 expression in chemo-resistant Ewing sarcoma cells. 2010 BMC Cancer
Timed inhibition of p38MAPK directs accelerated differentiation of human embryonic stem cells into cardiomyocytes. 2010 Cytotherapy
Pyramidal neurons are generated from oligodendroglial progenitor cells in adult piriform cortex. 2010 J Neurosci
myc maintains embryonic stem cell pluripotency and self-renewal. 2010 Differentiation
Cancer stem cells and microenvironment in prostate cancer progression. 2010 Horm Cancer
Surface immobilization of hexa-histidine-tagged adeno-associated viral vectors for localized gene delivery. 2010 Gene Ther
Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. 2010 Nature
Mitochondrial DNA mutations in disease and aging. 2010 Environ Mol Mutagen
Human amniotic fluid as a potential new source of organ specific precursor cells for future regenerative medicine applications. 2010 J Urol
Ofd1, a human disease gene, regulates the length and distal structure of centrioles. 2010 Dev Cell
A rapid pathway toward a superb gene delivery system: programming structural and functional diversity into a supramolecular nanoparticle library. 2010 ACS Nano
BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells. 2010 PLoS One
Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. 2010 Cell Stem Cell
Methylation of the retinoblastoma tumor suppressor by SMYD2. 2010 J Biol Chem
MicroRNAs as regulators of differentiation and cell fate decisions. 2010 Cell Stem Cell
Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension. 2010 Am J Physiol Cell Physiol
Inhibition of proteolysis of Delta-like-1 does not promote or reduce T-cell developmental potential. 2010 Immunol Cell Biol
T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell. 2010 Proc Natl Acad Sci U S A
The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers. 2010 PLoS One
Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo. 2010 Blood
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. 2010 Nat Protoc
Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. 2010 Nature
Visual activity regulates neural progenitor cells in developing xenopus CNS through musashi1. 2010 Neuron
p53 and stem cells: new developments and new concerns. 2010 Trends Cell Biol
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. 2010 Science
Cell replacement therapies to promote remyelination in a viral model of demyelination. 2010 J Neuroimmunol
skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. 2010 Proc Natl Acad Sci U S A
Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. 2010 Cell Stem Cell
Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord. 2010 PLoS One
Molecular and cellular approaches for diversifying and extending optogenetics. 2010 Cell
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. 2010 J Clin Invest
Histone demethylase LSD1 regulates neural stem cell proliferation. 2010 Mol Cell Biol
Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly. 2010 Mol Endocrinol
Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. 2010 J Alzheimers Dis
Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. 2010 PLoS One
Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells. 2010 Stem Cells
Preparation of adult muscle fiber-associated stem/precursor cells. 2010 Methods Mol Biol
Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. 2010 Science
Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. 2010 Blood
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. 2010 In Vitro Cell Dev Biol Anim
Multilayered specification of the T-cell lineage fate. 2010 Immunol Rev
Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. 2010 Hum Mol Genet
Microfluidic image cytometry for quantitative single-cell profiling of human pluripotent stem cells in chemically defined conditions. 2010 Lab Chip

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