Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
VEGF signaling has distinct spatiotemporal roles during heart valve development. 2010 Dev Biol
Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis. 2010 Cell Stem Cell
Inducible cardiomyocyte-specific gene disruption directed by the rat Tnnt2 promoter in the mouse. 2010 Genesis
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. 2010 J Clin Invest
Cancer stem cells and self-renewal. 2010 Clin Cancer Res
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. 2010 Arterioscler Thromb Vasc Biol
Role of nitric oxide signaling in endothelial differentiation of embryonic stem cells. 2010 Stem Cells Dev
Molecular signature of primary retinal pigment epithelium and stem-cell-derived RPE cells. 2010 Hum Mol Genet
A time-lapse and quantitative modelling analysis of neural stem cell motion in the absence of directional cues and in electric fields. 2010 J Neurosci Res
Tracking stem cell differentiation in the setting of automated optogenetic stimulation. 2010 Stem Cells
Genomic code for Sox10 activation reveals a key regulatory enhancer for cranial neural crest. 2010 Proc Natl Acad Sci U S A
A matrix micropatterning platform for cell localization and stem cell fate determination. 2010 Acta Biomater
Pancreatic beta-cell neogenesis by direct conversion from mature alpha-cells. 2010 Stem Cells
Prognostic value and function of KLF4 in prostate cancer: RNAa and vector-mediated overexpression identify KLF4 as an inhibitor of tumor cell growth and migration. 2010 Cancer Res
Homology modeling and deletion mutants of human nicotinamide mononucleotide adenylyltransferase isozyme 2: new insights on structure and function relationship. 2010 Protein Sci
SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: it's time to exchange! 2010 Exp Cell Res
Differential expression of stem cell markers in human follicular bulge and interfollicular epidermal compartments. 2010 Histochem Cell Biol
A model of motor neuron loss: selective deficits after ricin injection. 2010 J Neurotrauma
Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. 2010 Cell Stem Cell
HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. 2010 Mol Aspects Med
MicroRNAs as regulators of differentiation and cell fate decisions. 2010 Cell Stem Cell
Multipotent mesenchymal progenitor cells are present in endarterectomized tissues from patients with chronic thromboembolic pulmonary hypertension. 2010 Am J Physiol Cell Physiol
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. 2010 Stem Cells
Ofd1, a human disease gene, regulates the length and distal structure of centrioles. 2010 Dev Cell
A rapid pathway toward a superb gene delivery system: programming structural and functional diversity into a supramolecular nanoparticle library. 2010 ACS Nano
BMP-2/6 heterodimer is more effective than BMP-2 or BMP-6 homodimers as inductor of differentiation of human embryonic stem cells. 2010 PLoS One
Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. 2010 Nature
Expression of migration-related genes is progressively upregulated in murine Lineage-Sca-1+c-Kit+ population from the fetal to adult stages of development. 2010 Stem Cell Res Ther
Visual activity regulates neural progenitor cells in developing xenopus CNS through musashi1. 2010 Neuron
p53 and stem cells: new developments and new concerns. 2010 Trends Cell Biol
An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b. 2010 Science
Cell replacement therapies to promote remyelination in a viral model of demyelination. 2010 J Neuroimmunol
Inhibition of proteolysis of Delta-like-1 does not promote or reduce T-cell developmental potential. 2010 Immunol Cell Biol
The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers. 2010 PLoS One
Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo. 2010 Blood
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. 2010 Nat Protoc
Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly. 2010 Mol Endocrinol
Female human iPSCs retain an inactive X chromosome. 2010 Cell Stem Cell
Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. 2010 PLoS One
Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells. 2010 Stem Cells
Preparation of adult muscle fiber-associated stem/precursor cells. 2010 Methods Mol Biol
Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord. 2010 PLoS One
Molecular and cellular approaches for diversifying and extending optogenetics. 2010 Cell
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. 2010 Proc Natl Acad Sci U S A
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. 2010 J Clin Invest
Histone demethylase LSD1 regulates neural stem cell proliferation. 2010 Mol Cell Biol
Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. 2010 Hum Mol Genet
MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. 2010 Proc Natl Acad Sci U S A
Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. 2010 Stem Cells
Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. 2010 Blood

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