Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. 2012 J Neurosci
Full-length HLA-G1 and truncated HLA-G3 differentially increase HLA-E surface localization. 2012 Hum Immunol
Uncovering the role of genomic "dark matter" in human disease. 2012 J Clin Invest
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. 2012 Nature
Promotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone triiodothyronine-activated PI3K/AKT signal pathway. 2012 Biomaterials
Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS. 2012 Neuron
Reexamining hydroxamate inhibitors of botulinum neurotoxin serotype A: Extending towards the beta-exosite. 2012 Bioorg Med Chem Lett
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. 2012 Proc Natl Acad Sci U S A
Human ESC Self-Renewal Promoting miRNAs Induce Epithelial-Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGFbeta Tumor Suppressor Signaling Pathways. 2012 Mol Cancer Res
Wnt Signaling and Injury Repair. 2012 Cold Spring Harb Perspect Biol
A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. 2012 J Clin Invest
Three differentiation states risk-stratify bladder cancer into distinct subtypes. 2012 Proc Natl Acad Sci U S A
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. 2012 Integr Biol (Camb)
Modeling neurodevelopmental disorders using human neurons. 2012 Curr Opin Neurobiol
Correcting human mitochondrial mutations with targeted RNA import. 2012 Proc Natl Acad Sci U S A
APJ acts as a dual receptor in cardiac hypertrophy. 2012 Nature
MicroRNA profiling predicts a variance in the proliferative potential of cardiac progenitor cells derived from neonatal and adult murine hearts. 2012 J Mol Cell Cardiol
Single-injection HPLC method for rapid analysis of a combination drug delivery system. 2012 AAPS PharmSciTech
miR-125b Promotes Early Germ Layer Specification through Lin28/let-7d and Preferential Differentiation of Mesoderm in Human Embryonic Stem Cells. 2012 PLoS One
Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells. 2012 PLoS One
Library-free methylation sequencing with bisulfite padlock probes. 2012 Nat Methods
Gene expression commons: an open platform for absolute gene expression profiling. 2012 PLoS One
Modeling psychiatric disorders at the cellular and network levels. 2012 Mol Psychiatry
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. 2012 PLoS One
Advances in treatment and management: immunologic and cell-based regenerative therapies. 2012 Invest Ophthalmol Vis Sci
Dynamic expression of the Robo ligand Slit2 in bone marrow cell populations. 2012 Cell Cycle
Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model. 2012 Eur Cell Mater
Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. 2012 Cell Stem Cell
Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Cav2.3 calcium channels. 2012 J Gen Physiol
Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells. 2012 Stem Cells Dev
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. 2012 Stem Cells Dev
Wnt Inhibition Correlates with Human Embryonic Stem Cell Cardiomyogenesis: A Structure-Activity Relationship Study Based on Inhibitors for the Wnt Response. 2012 J Med Chem
Integrins Regulate Repulsion-Mediated Dendritic Patterning of Drosophila Sensory Neurons by Restricting Dendrites in a 2D Space. 2012 Neuron
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. 2012 PLoS One
Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells. 2012 Stem Cell Res
Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system. 2011 J Biol Chem
Extensive determination of glycan heterogeneity reveals an unusual abundance of high-mannose glycans in enriched plasma membranes of human embryonic stem cells. 2011 Mol Cell Proteomics
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol
Genome-Wide Binding Map of the HIV-1 Tat Protein to the Human Genome. 2011 PLoS One
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol
Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. 2011 Hum Mol Genet
Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders. 2011 J Child Psychol Psychiatry
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol
Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal. 2011 Proc Natl Acad Sci U S A
Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth. 2011 Cancer Cell
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. 2011 Proc Natl Acad Sci U S A
NMDA Mediated Contextual Conditioning Changes miRNA Expression. 2011 PLoS One
Defining the origins of Ras/p53-mediated squamous cell carcinoma. 2011 Proc Natl Acad Sci U S A

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