Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method. 2024 Nat Biotechnol
Generation of antigen-specific mature T cells from RAG1(-/-)RAG2(-/-)B2M(-/-) stem cells by engineering their microenvironment. 2024 Nat Biomed Eng
Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity. 2024 bioRxiv
H1FOO-DD promotes efficiency and uniformity in reprogramming to naive pluripotency. 2024 Stem Cell Reports
Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. 2024 ACS Nano
History and Current Status of Well-being Among Organizations (Impact of Wellness on a Section, Division, Institution and Profession, ACGME Requirements, Policies). 2024 Thorac Surg Clin
Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer. 2024 Cell Stem Cell
Human cerebellar organoids with functional Purkinje cells. 2024 Cell Stem Cell
Human iPSC-derived motor neuron innervation enhances the differentiation of muscle bundles engineered with benchtop fabrication techniques. 2024 bioRxiv
Identification of Disease-Relevant, Sex-Based Proteomic Differences in iPSC-Derived Vascular Smooth Muscle Cells. 2024 Int J Mol Sci
Implantation of autologous induced pluripotent stem cell-derived islets provides long-term insulin independence in a patient with type 1 diabetes. 2024 Am J Transplant
Implementation of Well-Being for Cardiothoracic Surgeons. 2024 Thorac Surg Clin
In vitro and in vivo modeling systems of supratentorial ependymomas. 2024 Front Oncol
Inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet. 2024 bioRxiv
Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. 2024 Aging Cell
Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications. 2024 Signal Transduct Target Ther
Inhibition of Ephrin B2 Reverse Signaling Abolishes Multiple Myeloma Pathogenesis. 2024 Cancer Res
Inhibition of IL-1 Ameliorates Cardiac Dysfunction and Arrhythmias in a Murine Model of Kawasaki Disease. 2024 Arterioscler Thromb Vasc Biol
Inhibition of Pyruvate Oxidation Diminishes Melanoma Progression. 2024 J Invest Dermatol
Integrated Single-Cell Analysis Reveals Spatially and Temporally Dynamic Heterogeneity in Fibroblast States during Wound Healing. 2024 J Invest Dermatol
Integration of Functional Polymers and Biosensors to Enhance Wound Healing. 2024 Adv Healthc Mater
Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses. 2024 bioRxiv
Isolation of Mouse Pancreatic Endothelial Cells. 2024 J Vis Exp
Label-free metabolic optical biomarkers track stem cell fate transition in real time. 2024 Sci Adv
Laminin Beta 2 Is Localized at the Sites of Blood-Brain Barrier and Its Disruption Is Associated With Increased Vascular Permeability, Histochemical, and Transcriptomic Study. 2024 J Histochem Cytochem
Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease. 2024 Mol Ther Methods Clin Dev
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells. 2024 Dev Cell
Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. 2024 Nat Med
Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility. 2024 Elife
Macrophages Contribute to Cardiac Fibrosis and Diastolic Dysfunction in Systemic Sclerosis. 2024 JACC Basic Transl Sci
Mechanistic Understanding of Enhancing Bioactivity via Bio-Ionic Liquids Functionalization of Biomaterials 2024 Applied Materials Today
Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas. 2024 Nat Commun
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. 2024 Neuron
Microglia protect against age-associated brain pathologies. 2024 Neuron
Microglia undergo sex-dimorphic transcriptional and metabolic rewiring during aging. 2024 J Neuroinflammation
Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. 2024 bioRxiv
Modulation of the JAK2-STAT3 pathway promotes expansion and maturation of human iPSCs-derived myogenic progenitor cells. 2024 bioRxiv
Molecular profiling of human blastocysts reveals primitive endoderm defects among embryos of decreased implantation potential. 2024 Cell Rep
Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells. 2024 Lab Chip
MYCT1 controls environmental sensing in human haematopoietic stem cells. 2024 Nature
Nanofiber-microwell cell culture system for spatially patterned differentiation of pluripotent stem cells in 3D. 2024 Mater Today Bio
Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling. 2024 Cell Rep
Neutrophil Granulopoiesis Optimized Through Ex Vivo Expansion of Hematopoietic Progenitors in Engineered 3D Gelatin Methacrylate Hydrogels. 2024 Adv Healthc Mater
Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance. 2024 bioRxiv
Non-canonical Wnt pathway expression in the developing mouse and human retina. 2024 Exp Eye Res
Non-coding RNA yREX3 from human extracellular vesicles exerts macrophage-mediated cardioprotection via a novel gene-methylating mechanism. 2024 Eur Heart J
Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping. 2024 Croat Med J
Ocular Mucous Membrane Pemphigoid Demonstrates a Distinct Autoantibody Profile from Those of Other Autoimmune Blistering Diseases: A Preliminary Study. 2024 Antibodies (Basel)
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy. 2024 Sci Adv
Oral bioavailability of a noncoding RNA drug, TY1, that acts on macrophages. 2024 bioRxiv