Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma. 2021 Sci Transl Med
Epigenetic silencing directs expression heterogeneity of stably integrated multi-transcript unit genetic circuits. 2021 Sci Rep
Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells. 2021 J Vis Exp
Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation. 2021 Elife
Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. 2021 J Neurotrauma
Global proteomic analyses of human cytotrophoblast differentiation/invasion. 2021 Development
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1. 2021 PLoS One
Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics. 2021 Front Pharmacol
Hematopoietic Stem Cell Gene Therapy for Cystinosis: From Bench-to-Bedside. 2021 Cells
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. 2021 Stem Cells
Human limbal epithelial stem cell regulation, bioengineering and function. 2021 Prog Retin Eye Res
Human neural stem cell-derived extracellular vesicles mitigate hallmarks of Alzheimer’s disease. 2021 Alzheimers Res Ther
Identification of neural oscillations and epileptiform changes in human brain organoids. 2021 Nat Neurosci
IFNgamma Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity. 2021 Cancer Discov
Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. 2021 Front Endocrinol (Lausanne)
In vitro safety “clinical trial” of the cardiac liability of drug polytherapy. 2021 Clin Transl Sci
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. 2021 Cell Rep
Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. 2021 Science
Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device. 2021 Cell Rep Med
Integrated spatial multiomics reveals fibroblast fate during tissue repair. 2021 Proc Natl Acad Sci U S A
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis. 2021 Nature
Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS. 2021 eNeuro
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models. 2021 Sci Transl Med
Limbal stem cell diseases. 2021 Exp Eye Res
Long-Term Hypoxia Maintains a State of Dedifferentiation and Enhanced Stemness in Fetal Cardiovascular Progenitor Cells. 2021 Int J Mol Sci
Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes. 2021 NPJ Regen Med
Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model. 2021 J Pediatr Surg
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. 2021 Cell Rep
Making Heads or Tails of the Large Mammalian Sinoatrial Node Micro-Organization. 2021 Circ Arrhythm Electrophysiol
Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival. 2021 Int J Mol Sci
Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI. 2021 J Nucl Med
Minimizing the risk of occupational Q fever exposure: A protocol for ensuring Coxiella burnetii-negative pregnant ewes are used for medical research. 2021 Lab Anim
Mitochondria as Playmakers of CAR T-cell Fate and Longevity. 2021 Cancer Immunol Res
Modeling preeclampsia using human induced pluripotent stem cells. 2021 Sci Rep
Multiple Treatment Cycles of Neural Stem Cell Delivered Oncolytic Adenovirus for the Treatment of Glioblastoma. 2021 Cancers (Basel)
N-terminal deletion of specific phosphorylation sites on PHOX2B disrupts the formation of enteric neurons in vivo. 2021 Am J Physiol Gastrointest Liver Physiol
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease. 2021 Science
Non-invasive intradermal imaging of cystine crystals in cystinosis. 2021 PLoS One
Non-Invasive Prenatal Test for beta-Thalassemia and Sickle Cell Disease Using Probe Capture Enrichment and Next-Generation Sequencing of DNA in Maternal Plasma. 2021 J Appl Lab Med
Normal IgH Repertoire Diversity in an Infant with ADA Deficiency After Gene Therapy. 2021 J Clin Immunol
Organophosphate Flame Retardants, Highly Fluorinated Chemicals, and Biomarkers of Placental Development and Disease During Mid-Gestation. 2021 Toxicol Sci
Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome. 2021 Proc Natl Acad Sci U S A
Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. 2021 Sci Transl Med
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. 2021 Biomater Sci
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. 2021 EMBO Mol Med
Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. 2021 J Surg Res
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. 2021 Science
Proangiogenic Collagen-Binding Glycan Therapeutic Promotes Endothelial Cell Angiogenesis. 2021 ACS Biomater Sci Eng
Regeneration of Jaw Joint Cartilage in Adult Zebrafish. 2021 Front Cell Dev Biol