| FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. |
2025 |
Nat Commun |
| Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. |
2025 |
Nat Protoc |
| Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. |
2025 |
Stem Cell Res |
| Genome editing with programmable base editors in human cells. |
2025 |
Methods Enzymol |
| Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. |
2025 |
Genes Dev |
| Identification of CD84 as a potent survival factor in acute myeloid leukemia. |
2025 |
J Clin Invest |
| Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. |
2025 |
NPJ Precis Oncol |
| IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes. |
2025 |
Nat Commun |
| Implantation of engineered adipocytes suppresses tumor progression in cancer models. |
2025 |
Nat Biotechnol |
| Integrated Longitudinal Transcriptomic and Proteomic Analysis of the Murine Lung Response to Influenza A Virus. |
2025 |
Am J Respir Cell Mol Biol |
| Integrated workflow for analysis of immune enriched spatial proteomic data with IMmuneCite. |
2025 |
Sci Rep |
| Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses. |
2025 |
Gut Microbes |
| Intravenous and intracranial GD2-CAR T cells for H3K27M(+) diffuse midline gliomas. |
2025 |
Nature |
| Large language model agents can use tools to perform clinical calculations. |
2025 |
NPJ Digit Med |
| LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK. |
2025 |
Mol Metab |
| Limbal epithelial cells detected in stage III limbal stem cell deficiency by multimodal anterior segment imaging. |
2025 |
Am J Ophthalmol |
| Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. |
2025 |
bioRxiv |
| Menthol, a consumer product additive, adversely affects human embryonic stem cells via activation of TRPM8 and TRPA1 channels. |
2025 |
Stem Cells Transl Med |
| Micropatterning Photoconductive Peptide Assemblies on Stiff and Soft Biomaterial Substrates. |
2025 |
ACS Appl Mater Interfaces |
| Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. |
2025 |
Brain Behav Immun |
| Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathology. |
2025 |
bioRxiv |
| Neuroendocrinology and the Genetics of Obesity. |
2025 |
Endocrinology |
| Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. |
2025 |
Nat Commun |
| On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. |
2025 |
Biosensors (Basel) |
| Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells. |
2025 |
Med |
| PHLDA2 promotes breast cancer metastasis by co-opting a developmental program for placental vascular remodeling. |
2025 |
bioRxiv |
| Probing DNA damage in Rett syndrome neurons uncovers a role for MECP2 regulation of PARP1. |
2025 |
Stem Cell Reports |
| Proof of concept for brain organoid-on-a-chip to create multiple domains in forebrain organoids. |
2025 |
RSC Adv |
| Proteasome inhibition enhances oncolytic reovirus therapy in multiple myeloma independently of its direct cytotoxic effects. |
2025 |
J Hematol Oncol |
| Protocol to study ductal progenitor-like cells from the adult human pancreas using 3D suspension and methylcellulose-based culture systems. |
2025 |
STAR Protoc |
| PTPN2 Regulates Iron Handling Protein Expression in Inflammatory Bowel Disease Patients and Prevents Iron Deficiency in Mice. |
2025 |
Int J Mol Sci |
| Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo. |
2025 |
J Clin Invest |
| Reversible proliferative arrest induced by rapid depletion of RNase MRP. |
2025 |
Nat Commun |
| Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens. |
2025 |
Cell |
| Size and Structural Control of Mechanoluminescent ZnS:Mn(2+) Nanocrystals for Optogenetic Neuromodulation. |
2025 |
ACS Nano |
| Spatial and Single-Cell Transcriptomics Reveal Keratinocytes as Key Players in Vulvar Lichen Sclerosus Pathogenesis. |
2025 |
J Invest Dermatol |
| Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling. |
2025 |
Cell Stem Cell |
| Spinal Cord Injury in Real Time: Intra-Operative Ultrasound for Acute Phase Examination in Non-Human Primates. |
2025 |
Brain Sci |
| Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. |
2025 |
J Biol Chem |
| Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. |
2025 |
Proc Natl Acad Sci U S A |
| Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development. |
2025 |
Geroscience |
| The Proteostasis Network is a Therapeutic Target in Acute Myeloid Leukemia. |
2025 |
Blood |
| The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis. |
2025 |
Gut Microbes |
| The UCSC Genome Browser database: 2025 update. |
2025 |
Nucleic Acids Res |
| Therapeutic genetic restoration through allogeneic brain microglia replacement. |
2025 |
Nature |
| Understanding human embryogenesis by building programmable stem cell-based models. |
2025 |
Trends Cell Biol |
| Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. |
2025 |
Nat Commun |
| VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment. |
2025 |
bioRxiv |
| Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology. |
2025 |
Nat Commun |
| Wnt/beta-catenin maintains epithelial IL-33 in the colonic stem and progenitor cell niche and drives its induction in colitis. |
2025 |
Mucosal Immunol |
