Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Future regenerative therapies for corneal disease. 2023 Curr Opin Ophthalmol
Graft conditioning with fluticasone propionate reduces graft-versus-host disease upon allogeneic hematopoietic cell transplantation in mice. 2023 EMBO Mol Med
Graphene-based cardiac sensors and actuators. 2023 Front Bioeng Biotechnol
GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development. 2023 iScience
Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression. 2023 Nat Methods
How and Why the Circadian Clock Regulates Proliferation of Adult Epithelial Stem Cells. 2023 Stem Cells
Human enteroids as a tool to study conventional and ultra-high dose rate radiation. 2023 Integr Biol (Camb)
Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration. 2023 Stem Cell Reports
Identification of SALL4 Expressing Islet-1+ Cardiovascular Progenitor Cell Clones. 2023 Int J Mol Sci
In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles. 2023 Bioact Mater
In vitro formation and extended culture of highly metabolically active and contractile tissues. 2023 PLoS One
Inclusion of 4-1BB Costimulation Enhances Selectivity and Functionality of IL13Ralpha2-Targeted Chimeric Antigen Receptor T Cells. 2023 Cancer Res Commun
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis. 2023 Proc Natl Acad Sci U S A
Latent diffusion augmentation enhances deep learning analysis of neuro-morphology in limbal stem cell deficiency. 2023 Front Med (Lausanne)
Ligament injury in adult zebrafish triggers ECM remodeling and cell dedifferentiation for scar-free regeneration. 2023 NPJ Regen Med
LincRNA-Cox2 Regulates Smoke-induced Inflammation in Murine Macrophages. 2023 Am J Respir Cell Mol Biol
Long-term effects of vaginal surgery and endogenous ovarian hormones on the vagina and bladder. 2023 Sex Med
Mapping Human Skin: One Sequenced Cell at a Time. 2023 J Invest Dermatol
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model. 2023 iScience
Modeling brain macrophage biology and neurodegenerative diseases using human iPSC-derived neuroimmune organoids. 2023 Front Cell Neurosci
Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI. 2023 Res Sq
Neonatal Cardiovascular-Progenitor-Cell-Derived Extracellular Vesicles Activate YAP1 in Adult Cardiac Progenitor Cells. 2023 Int J Mol Sci
Neurons require glucose uptake and glycolysis in vivo. 2023 Cell Rep
Ocular Surface Regeneration by Limbal Stem Cells Therapies: State of the Art, Challenges, and Perspectives. 2023 Stem Cells Transl Med
OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis. 2023 Proc Natl Acad Sci U S A
Patient-derived SLC6A1 variant S295L results in an epileptic phenotype similar to haploinsufficient mice. 2023 Epilepsia
Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2. 2023 bioRxiv
Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition. 2023 bioRxiv
Preferential FGF18/FGFR activity in pseudoglandular versus canalicular stage human lung fibroblasts. 2023 Front Cell Dev Biol
Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis. 2023 Nat Genet
Present and Future Modeling of Human Psychiatric Connectopathies With Brain Organoids. 2023 Biol Psychiatry
Presentation of Human Neural Stem Cell Antigens Drives Regulatory T Cell Induction. 2023 J Immunol
Profiling of repetitive RNA sequences in the blood plasma of patients with cancer. 2023 Nat Biomed Eng
PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice. 2023 Cell Mol Gastroenterol Hepatol
PTPN2 regulates bacterial clearance in a mouse model of enteropathogenic and enterohemorrhagic E. coli infection. 2023 JCI Insight
Purification and functional characterization of novel human skeletal stem cell lineages. 2023 Nat Protoc
Pushing the boundaries of brain organoids to study Alzheimer’s disease. 2023 Trends Mol Med
Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors. 2023 Hum Mol Genet
RNA editing: Expanding the potential of RNA therapeutics. 2023 Mol Ther
RNA splicing factor Rbm25 underlies heterogeneous preleukemic clonal expansion in mice. 2023 Blood
Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis. 2023 Nat Commun
Signalling by senescent melanocytes hyperactivates hair growth. 2023 Nature
Single mRNA detection of Wnt signaling pathway in the human limbus. 2023 Exp Eye Res
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. 2023 Sci Adv
Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. 2023 iScience
SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs. 2023 Development
Sonogenetic control of multiplexed genome regulation and base editing. 2023 Nat Commun
Stable expression of large transgenes via the knock-in of an integrase-deficient lentivirus. 2023 Nat Biomed Eng
Stem Cell-Based Organoid Models of Neurodevelopmental Disorders. 2023 Biol Psychiatry
Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. 2023 Elife