| Spinal Cord Injury in Real Time: Intra-Operative Ultrasound for Acute Phase Examination in Non-Human Primates. |
2025 |
Brain Sci |
| Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. |
2025 |
J Biol Chem |
| Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. |
2025 |
Proc Natl Acad Sci U S A |
| The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis. |
2025 |
Gut Microbes |
| The UCSC Genome Browser database: 2025 update. |
2025 |
Nucleic Acids Res |
| Therapeutic genetic restoration through allogeneic brain microglia replacement. |
2025 |
Nature |
| Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. |
2025 |
Nat Commun |
| A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-gamma-induced CD38 expression. |
2024 |
Blood |
| A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis. |
2024 |
Elife |
| A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. |
2024 |
Exp Neurol |
| A fibroblast-dependent TGF-beta1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. |
2024 |
J Clin Invest |
| A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. |
2024 |
Nat Commun |
| A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS. |
2024 |
Nature |
| A maternal brain hormone that builds bone. |
2024 |
Nature |
| A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. |
2024 |
Mol Ther Methods Clin Dev |
| A Panoramic View of Cell Population Dynamics in Mammalian Aging. |
2024 |
bioRxiv |
| A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. |
2024 |
Nat Commun |
| A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. |
2024 |
Proc Natl Acad Sci U S A |
| Acid-degradable lipid nanoparticles enhance the delivery of mRNA. |
2024 |
Nat Nanotechnol |
| Activation of ductal progenitor-like cells from adult human pancreas requires extracellular matrix protein signaling. |
2024 |
iScience |
| Age-associated imbalance in immune cell regeneration varies across individuals and arises from a distinct subset of stem cells. |
2024 |
Cell Mol Immunol |
| AMPK Drives both Glycolytic and Oxidative Metabolism in Murine and Human T Cells During Graft-versus-host Disease. |
2024 |
Blood Adv |
| An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. |
2024 |
Cell |
| An Endothelial Cell Is Not Simply an Endothelial Cell. |
2024 |
Stem Cells Dev |
| An experimental census of retrons for DNA production and genome editing. |
2024 |
bioRxiv |
| An improved method for generating human spinal cord neural stem cells. |
2024 |
Exp Neurol |
| Ancestral Diversity of Skin Reaches Single-Cell Resolution. |
2024 |
J Invest Dermatol |
| Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy. |
2024 |
bioRxiv |
| Antisense oligonucleotide therapy in an individual with KIF1A-associated neurological disorder. |
2024 |
Nat Med |
| Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. |
2024 |
Nat Commun |
| Atypical KCNQ1/Kv7 channel function in a neonatal diabetes patient: Hypersecretion preceded the failure of pancreatic beta-cells. |
2024 |
iScience |
| CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes. |
2024 |
Nat Commun |
| Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions. |
2024 |
Nat Neurosci |
| Charting and probing the activity of ADARs in human development and cell-fate specification. |
2024 |
Nat Commun |
| Chitosan-Polyethylene Glycol Inspired Polyelectrolyte Complex Hydrogel Templates Favoring NEO-Tissue Formation for Cardiac Tissue Engineering. |
2024 |
Gels |
| Circadian Clock in Muscle Disease Etiology and Therapeutic Potential for Duchenne Muscular Dystrophy. |
2024 |
Int J Mol Sci |
| Collagen scaffold-seeded iTenocytes accelerate the healing and functional recovery of Achilles tendon defects in a rat model. |
2024 |
Front Bioeng Biotechnol |
| Comparing fabrication techniques for engineered cardiac tissue. |
2024 |
J Biomed Mater Res A |
| Conductive Microgel Annealed Scaffolds Enhance Myogenic Potential of Myoblastic Cells. |
2024 |
Adv Healthc Mater |
| Conserved and divergent features of trophoblast stem cells. |
2024 |
J Mol Endocrinol |
| Continuous multiplexed phage genome editing using recombitrons. |
2024 |
Nat Biotechnol |
| CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. |
2024 |
Cell Stem Cell |
| Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. |
2024 |
Biomaterials |
| Decellularized Extracellular Matrix Improves Mesenchymal Stromal Cell Spheroid Response to Chondrogenic Stimuli. |
2024 |
Tissue Eng Part A |
| Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. |
2024 |
Sci Adv |
| Dendrite injury triggers neuroprotection in Drosophila models of neurodegenerative disease. |
2024 |
Sci Rep |
| Development of neuronal timescales in human cortical organoids and rat hippocampus dissociated cultures. |
2024 |
J Neurophysiol |
| Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity. |
2024 |
Diabetologia |
| Directed Differentiation of Neurons from Human iPSCs for Modeling Neurological Disorders. |
2024 |
Methods Mol Biol |
| Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. |
2024 |
Elife |
