| Elevated Senescence Markers in Developing Trisomy 21 Human Lungs. |
2025 |
Am J Respir Cell Mol Biol |
| Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis. |
2025 |
Nat Commun |
| Enhanced neuromorphogenesis of neural stem cells via the optimization of physical stimulus-responsive signaling pathways. |
2025 |
Stem Cell Res Ther |
| Epigenetic Upregulation of Carotid Body Angiotensin Signaling Increases Blood Pressure. |
2025 |
Hypertension |
| Every cell every gene all at once: Systems genetic approaches toward corticogenesis. |
2025 |
Curr Opin Neurobiol |
| Evidence of neuronal DNA damage in the brains of patients with Rett syndrome. |
2025 |
Dis Model Mech |
| Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape. |
2025 |
Science |
| Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. |
2025 |
Cancer Discov |
| Expansion of human pluripotent stem cell-induced nephron progenitor cells (iNPCs) and the generation of nephron organoids from iNPCs. |
2025 |
Nat Protoc |
| F.O.R.W.A.R.D: A Data-Driven Framework for Network-Based Target Prioritization in Drug Discovery. |
2025 |
bioRxiv |
| Functional Neurogenomics to Dissect Disease Mechanisms Across Models. |
2025 |
Annu Rev Genomics Hum Genet |
| FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. |
2025 |
Nat Commun |
| Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. |
2025 |
Nat Protoc |
| Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. |
2025 |
Stem Cell Res |
| Genome editing with programmable base editors in human cells. |
2025 |
Methods Enzymol |
| Highly efficient in vivo hematopoietic stem cell transduction using an optimized self-complementary adeno-associated virus. |
2025 |
Mol Ther Methods Clin Dev |
| Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. |
2025 |
Genes Dev |
| Human embryo implantation in vitro: a standardized framework for basic research and clinical translation. |
2025 |
Fertil Steril |
| Identification of CD84 as a potent survival factor in acute myeloid leukemia. |
2025 |
J Clin Invest |
| Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. |
2025 |
NPJ Precis Oncol |
| IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes. |
2025 |
Nat Commun |
| Implantation of engineered adipocytes suppresses tumor progression in cancer models. |
2025 |
Nat Biotechnol |
| In utero lipid nanoparticle delivery achieves robust editing in hematopoietic stem cells. |
2025 |
bioRxiv |
| Integrated Longitudinal Transcriptomic and Proteomic Analysis of the Murine Lung Response to Influenza A Virus. |
2025 |
Am J Respir Cell Mol Biol |
| Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular composition and X-chromosome inactivation. |
2025 |
bioRxiv |
| Integrated workflow for analysis of immune enriched spatial proteomic data with IMmuneCite. |
2025 |
Sci Rep |
| Intestinal epithelial PTPN2 limits pathobiont colonization by immune-directed antimicrobial responses. |
2025 |
Gut Microbes |
| Intra-amniotic antisense oligonucleotide treatment improves phenotypes in preclinical models of spinal muscular atrophy. |
2025 |
Sci Transl Med |
| Intravenous and intracranial GD2-CAR T cells for H3K27M(+) diffuse midline gliomas. |
2025 |
Nature |
| KIF5A downregulation in spinal muscular atrophy links axonal regeneration defects with ALS. |
2025 |
bioRxiv |
| Large language model agents can use tools to perform clinical calculations. |
2025 |
NPJ Digit Med |
| LGR4 is essential for maintaining beta-cell homeostasis through suppression of RANK. |
2025 |
Mol Metab |
| Limbal epithelial cells detected in stage III limbal stem cell deficiency by multimodal anterior segment imaging. |
2025 |
Am J Ophthalmol |
| Lineage-resolved atlas of the developing human cortex. |
2025 |
Nature |
| Long noncoding RNA BCYRN1 promotes cardioprotection by enhancing human and murine regulatory T cell dynamics. |
2025 |
J Clin Invest |
| Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency. |
2025 |
N Engl J Med |
| Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. |
2025 |
bioRxiv |
| Measurement and clinical interpretation of CRISPR off-targets. |
2025 |
Nat Genet |
| Menthol, a consumer product additive, adversely affects human embryonic stem cells via activation of TRPM8 and TRPA1 channels. |
2025 |
Stem Cells Transl Med |
| Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1. |
2025 |
Nature |
| Micropatterning Photoconductive Peptide Assemblies on Stiff and Soft Biomaterial Substrates. |
2025 |
ACS Appl Mater Interfaces |
| Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. |
2025 |
Brain Behav Immun |
| Molecular Signatures in Cortical Development. |
2025 |
Annu Rev Neurosci |
| Morphogen-guided neocortical organoids recapitulate regional areal identity and model neurodevelopmental disorder pathology. |
2025 |
bioRxiv |
| Neuroendocrinology and the Genetics of Obesity. |
2025 |
Endocrinology |
| Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics. |
2025 |
Nat Commun |
| On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. |
2025 |
Biosensors (Basel) |
| Opposing roles of p38alpha-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy. |
2025 |
Cell Rep |
| Overcoming ovarian cancer resistance and evasion to CAR-T cell therapy by harnessing allogeneic CAR-NKT cells. |
2025 |
Med |
| Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers. |
2025 |
bioRxiv |
