Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Systematic Identification of Barriers to Human iPSC Generation. 2014 Cell
Targeted delivery of mesenchymal stem cells to the bone. 2014 Bone
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. 2014 Cell Stem Cell
Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. 2014 J Neurosci
Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a. 2014 Development
Technical Variations in Low-Input RNA-seq Methodologies. 2014 Sci Rep
Techniques to monitor glycolysis. 2014 Methods Enzymol
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. 2014 EMBO Mol Med
TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model. 2014 Mol Cell Biol
The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny. 2014 PLoS One
The antibody response of pregnant Cameroonian women to VAR2CSA ID1-ID2a, a small recombinant protein containing the CSA-binding site. 2014 PLoS One
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. 2014 Nat Cell Biol
The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells. 2014 Elife
The effect of multivalent Sonic hedgehog on differentiation of human embryonic stem cells into dopaminergic and GABAergic neurons. 2014 Biomaterials
The past, present and future of stem cell clinical trials for ALS. 2014 Exp Neurol
The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. 2014 Proc Natl Acad Sci U S A
Therapeutic potential of placenta-derived stem cells for liver diseases: Current status and perspectives. 2014 J Obstet Gynaecol Res
Tissue engineering: construction of a multicellular 3D scaffold for the delivery of layered cell sheets. 2014 J Vis Exp
Tracking migration during human T cell development. 2014 Cell Mol Life Sci
Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement. 2014 J Am Coll Cardiol
Translational Profiles of Medullary Myofibroblasts during Kidney Fibrosis. 2014 J Am Soc Nephrol
Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming. 2014 Cell Stem Cell
Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential. 2014 Stem Cell Reports
Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. 2014 Endocrinology
Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration. 2014 Adv Exp Med Biol
Wnt signaling regulates homeostasis of the periodontal ligament. 2014 J Periodontal Res
Wnt/Catenin Signaling in Adult Stem Cell Physiology and Disease. 2014 Stem Cell Rev
WNT3A promotes myogenesis of human embryonic stem cells and enhances in vivo engraftment. 2014 Sci Rep
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. 2014 Cell
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. 2014 Nat Med
A “living bioreactor” for the production of tissue-engineered small intestine. 2013 Methods Mol Biol
A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis. 2013 Elife
A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells. 2013 FASEB J
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. 2013 Cancer Discov
A dynamic population of stromal cells contributes to the follicle stem cell niche in the Drosophila ovary. 2013 Development
A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. 2013 Blood
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation. 2013 Proc Natl Acad Sci U S A
A High-Resolution Enhancer Atlas of the Developing Telencephalon. 2013 Cell
A high-resolution map of the three-dimensional chromatin interactome in human cells. 2013 Nature
A localized Wnt signal orients asymmetric stem cell division in vitro. 2013 Science
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. 2013 Cell Stem Cell
A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. 2013 Nat Neurosci
A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal. 2013 Cancer Cell
A regenerative approach to the treatment of multiple sclerosis. 2013 Nature
A robust method to derive functional neural crest cells from human pluripotent stem cells. 2013 Am J Stem Cells
A small molecule inhibitor of redox-regulated protein translocation into mitochondria. 2013 Dev Cell
A Three-Dimensional Culture Method to Expand Limbal Stem/Progenitor Cells. 2013 Tissue Eng Part C Methods
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. 2013 Cell Stem Cell
Acute stress enhances adult rat hippocampal neurogenesis and activation of newborn neurons via secreted astrocytic FGF2. 2013 Elife (Cambridge)
Adding an unnatural covalent bond to proteins through proximity-enhanced bioreactivity. 2013 Nat Methods