Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Large-scale production of lentiviral vector in a closed system hollow fiber bioreactor. 2015 Mol Ther Methods Clin Dev
Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle. 2015 Nat Commun
Light-activated RNA interference in human embryonic stem cells. 2015 Biomaterials
Limbal Basal Cell Density Decreases in Limbal Stem Cell Deficiency. 2015 Am J Ophthalmol
Long-Term Controlled Protein Release from Poly(Ethylene Glycol) Hydrogels by Modulating Mesh Size and Degradation. 2015 Macromol Biosci
Low- and high-LET radiation drives clonal expansion of lung progenitor cells in vivo. 2015 Radiat Res
Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs. 2015 Cell Stem Cell
Lysophosphatidic acid mediates fibrosis in injured joints by regulating collagen type I biosynthesis. 2015 Osteoarthritis Cartilage
Machine-Learning-Based Analysis in Genome-Edited Cells Reveals the Efficiency of Clathrin-Mediated Endocytosis. 2015 Cell Rep
Mammary Stem Cell Self-Renewal Is Regulated by Slit2/Robo1 Signaling through SNAI1 and mINSC. 2015 Cell Rep
Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia. 2015 Nat Immunol
Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development. 2015 BMC Biol
Mesenchymal Stem Cells Respond to Hypoxia by Increasing Diacylglycerols. 2015 J Cell Biochem
Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines. 2015 Stem Cell Reports
Molecular basis of embryonic stem cell self-renewal: from signaling pathways to pluripotency network. 2015 Cell Mol Life Sci
MTA3 regulates differentiation of human cytotrophoblast stem cells. 2015 Placenta
Multiple intravenous injections of allogeneic equine mesenchymal stem cells do not induce a systemic inflammatory response but do alter lymphocyte subsets in healthy horses. 2015 Stem Cell Res Ther
Musashi signaling in stem cells and cancer. 2015 Annu Rev Cell Dev Biol
Natural large-scale regeneration of rib cartilage in a mouse model. 2015 J Bone Miner Res
NDEx, the Network Data Exchange. 2015 Cell Syst
Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy. 2015 Elife
Neural Stem Cells in Stroke: Intracerebral Approaches 2015 Springer; Cell Therapy for Brain Injury
Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion. 2015 Cell
New insights into the conserved mechanism of pluripotency maintenance. 2015 Curr Opin Genet Dev
Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness. 2015 Sci Rep
Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. 2015 Dev Cell
Novel monoclonal antibodies to study tissue regeneration in planarians. 2015 BMC Dev Biol
Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments. 2015 Neuron
NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer. 2015 Hepatology
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. 2015 Cell Rep
Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice. 2015 Hepatology
Paraoxon and Pyridostigmine Interfere with Neural Stem Cell Differentiation. 2015 Neurochem Res
Persistent oxidative stress in human neural stem cells exposed to low fluences of charged particles. 2015 Redox Biol
Personalized medicine for effective Alzheimer disease treatment. 2015 JAMA Neurol
Ph+ ALL: drawing strength from a benign past. 2015 Blood
Placental mesenchymal stromal cells rescue ambulation in ovine myelomeningocele. 2015 Stem Cells Transl Med
Pluripotent stem cell energy metabolism: an update. 2015 EMBO J
Polarized human embryonic stem cell-derived retinal pigment epithelial cell monolayers have higher resistance to oxidative stress-induced cell death than nonpolarized cultures. 2015 Stem Cells Transl Med
Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro. 2015 Stem Cells Dev
PPARs and ERRs: molecular mediators of mitochondrial metabolism. 2015 Curr Opin Cell Biol
Predicting the human epigenome from DNA motifs. 2015 Nat Methods
Progressive Chromatin Condensation and H3K9 Methylation Regulate the Differentiation of Embryonic and Hematopoietic Stem Cells. 2015 Stem Cell Reports
Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson’s disease. 2015 Cell Transplant
Quantifying cell-induced matrix deformation in three dimensions based on imaging matrix fibers. 2015 Integr Biol (Camb)
Rationale for targeting the pre-B-cell receptor signaling pathway in acute lymphoblastic leukemia. 2015 Blood
Reengineering autologous bone grafts with the stem cell activator WNT3A. 2015 Biomaterials
Replication Stress and Telomere Dysfunction Are Present in Cultured Human Embryonic Stem Cells. 2015 Cytogenet Genome Res
REST/NRSF Knockdown Alters Survival, Lineage Differentiation and Signaling in Human Embryonic Stem Cells. 2015 PLoS One
Resveratrol inhibits epithelial-mesenchymal transition of retinal pigment epithelium and development of proliferative vitreoretinopathy. 2015 Sci Rep
Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis. 2015 PLoS One