| Conference – 2025 CIRM Trainee Network Conference | Dr. Francesca Mariani | Manage the 2024 CIRM Annual Trainee Network Conference |
$348,626 |
| Shared Labs Grant – Enhancing/Expanding SRLs | Dr. Nils O. Lindstrom | CIRM ASCEND Center – Advancing Stem Cell Education and Novel Discoveries |
$3,663,163 |
| Manufacturing Network Grant | Mohamed Abou-el-Enein | Advancing Cell Therapy Manufacturing Through Collaboration |
$1,999,964 |
| Discovery Research Projects | Preet M Chaudhary | Chimeric Antigen Receptor Targeting Spike Glycoprotein of SARS-cov2 |
$248,125 |
| Discovery Research Projects | Dr. Justin K Ichida | Development of a novel PIKFYVE kinase inhibitor for the treatment of COVID-19 |
$140,067 |
| Alpha Stem Cell Clinics Network Expansion | Thomas Buchanan | Alpha Clinic Network Expansion for Cell and Gene Therapies |
$7,999,983 |
| Quest – Discovery Stage Research Projects | Dr. Justin K Ichida | Development of a VAV2 antisense oligonucleotide (ASO) treatment for ALS |
$2,072,560 |
| Quest – Discovery Stage Research Projects | Dr Linda Sher M.D. | Assessing the Functional, Immunologic and Microbiologic Characteristics of Human Livers Created in Chimeric Pigs |
$2,736,590 |
| Quest – Discovery Stage Research Projects | Dr. Justin K Ichida | Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS |
$222,300 |
| Quest – Discovery Stage Research Projects | Dr. Neil Segil | A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs |
$741,574 |
| Inception – Discovery Stage Research Projects | Biju B. Thomas | A Novel Tissue Engineering Technique to Repair Degenerated Retina |
$215,133 |
| Therapeutic Translational Research Projects | David D. Tran | A Novel Gene Therapy to Target Glioblastoma via Custom-Engineered Adenovirus-Associated Viral Vectors |
$5,927,454 |
| Therapeutic Translational Research Projects | Dr. Rongfu Wang | Novel T cell receptor-STEM T cell immunotherapy in lung cancer |
$5,689,540 |
| Therapeutic Translational Research Projects | Preet M Chaudhary | Next generation affinity-tuned CAR for prostate cancer |
$5,805,144 |
| Therapeutic Translational Research Projects | Dr. Mark S Humayun | PRPE-SF, polarized hESC-derived RPE Soluble Factors, as a Therapy for Early Stage Dry Age-related Macular Degeneration |
$3,697,935 |
| Therapeutic Translational Research Projects | Dr. Denis A Evseenko Dr. | Pluripotent stem cell-derived chondrocytes for articular cartilage repair |
$2,503,104 |
| Conference II | Dr. Yang Chai | 2023 Dental, Oral, & Craniofacial Tissue Regeneration Consortium (DOCTRC) 4th Annual Joint Retreat/Conference |
$47,538 |
| Conference II | Qifa Zhou | The 15th International Conference on the Ultrasound Engineering and Biomedical Applications |
$21,165 |
| Conference II | Dr. Justin K Ichida | The 7th Annual California ALS research network and PAC10 meeting |
$10,830 |
| Late Stage Preclinical Projects | Dr. Mark S Humayun | IND-enabling program for PRPE-SF, the secretome from polarized stem cell-derived RPE cells, for the treatment of dry-age related macular degeneration |
$5,993,562 |
| Late Stage Preclinical Projects | Dr. Denis A Evseenko Dr. | Plurocart: a novel stem cell-based implant for articular cartilage restoration |
$5,999,782 |
| Tools and Technologies III | Dr. Qilong Ying | Embryonic stem cell-based generation of rat models for assessing human cellular therapies |
$1,326,979 |
| Tools and Technologies III | Dr. Paula M. Cannon | Site-specific gene editing in hematopoietic stem cells as an anti-HIV therapy |
$1,495,665 |
| Tools and Technologies III | Dr. Toshio Miki | Development of a clinical-grade extracorporeal liver support system using human induced pluripotent stem cell-derived hepatic cells |
$1,257,011 |
| Conference | Qing Liu-Michael | USC/UCSF/UCLA Tri-Institutional Stem Cell Retreat |
$5,000 |
| Conference | Kathy Rich | The Stem Cell Niche in Development and Regeneration |
$7,476 |
| Disease Team Planning | Dr. Mark S Humayun | Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) |
$3,088 |
| Disease Team Planning | Dr. David Timothy Woodley | Clinical Regenerative Wound Healing With Stem Cells |
$33,626 |
| Major Facilities | Dr. Chrysostomos L. Max Nikias | Broad CIRM Facility at USC |
$26,972,500 |
| Basic Biology V | Dr. Denis A Evseenko Dr. | Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes |
$735,138 |
| Disease Team Therapy Development III | Dr. Mark S Humayun | Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration |
$16,339,827 |
| Creativity Awards | Roberta Diaz Brinton | CIRM STAR High School Summer Research and Creativity Program |
$271,160 |
| Early Translational III | Dr. Toshio Miki | Generation of hepatic cell from placental stem cell for congenital metabolic disorders |
$1,750,375 |
| Training Grant I-1 | Dr. Robert E Maxson | CIRM Stem Cell Biology Training Grant |
$2,332,431 |
| Disease Team Therapy Planning I | Roberta Diaz Brinton | A CIRM Disease Team to Develop Allopregnanolone for Prevention and Treatment of Alzheimer’s Disease |
$107,961 |
| Research Training II | Dr. Robert E Maxson | CIRM Stem Cell Biology Training Program |
$5,827,817 |
| Research Leadership | Dr. Andrew McMahon | Repair and regeneration of the nephron |
$5,672,206 |
| New Faculty I | Dr. Mohammad Pashmforoush | Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors |
$2,816,578 |
| New Faculty I | Dr. Songtao Shi | Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells |
$3,242,651 |
| Transplantation Immunology | Dr. Terrence Christopher Town | Role of HLA in neural stem cell rejection using humanized mice |
$353,249 |
| Tools and Technologies I | Dr. Pin Wang | Development of Baculoviral Vectors for Gene Editing of Human Stem Cells |
$945,604 |
| Shared Labs | Dr. Martin Pera | USC Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research |
$1,724,015 |
| Shared Labs | Dr. Andrew McMahon | USC Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research |
$3,411,861 |
| New Faculty II | Dr. Qilong Ying | Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation |
$2,261,174 |
| New Faculty II | Dr. Gage Crump | Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw |
$2,247,403 |
| New Cell Lines | Dr. Martin Pera | New Technology for the Derivation of Human Pluripotent Stem Cell Lines for Clinical Use |
$1,266,134 |
| SEED Grant | Dr. Qilong Ying | Self-renewal of human embryonic stem cells |
$621,421 |
| SEED Grant | Dr. David R. Hinton | Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. |
$651,607 |
| SEED Grant | Dr. Peter W Laird | Screening for Oncogenic Epigenetic Alterations in Human ES Cells |
$647,431 |
| SEED Grant | Dr. Wange Lu | Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling |
$624,000 |
| Disease Team Research I | Dr. Mark S Humayun | Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) |
$18,904,916 |
| Basic Biology I | Dr. Martin Pera | The stem cell microenvironment in the maintenance of pluripotency and reprogramming |
$1,325,723 |
| Basic Biology I | Dr. Wange Lu | Defining the molecular mechanisms of somatic cell reprogramming |
$1,365,580 |
| COMPASS Training Grant | Dr. Senta Georgia | USC COMPASS: Guiding Undergraduates to Careers in Regenerative Medicine |
$2,899,999 |
| Research Training Grant | Dr. Francesca Mariani | Training Program Bridging Stem Cell Research with Clinical Applications in Regenerative Medicine |
$5,373,742 |
