University of Southern California

Total Awards: 
45
Award Value: 
$142,067,205
Major Facility Name: 
Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research
Institution type: 
Not for profit
Short Name: 
USC
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Awards to the Institution

Program Investigator Award Title Award Value
Basic Biology V Denis Evseenko Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $735,138
Therapeutic Translational Research Projects PREET Chaudhary Next generation affinity-tuned CAR for prostate cancer $5,805,144
Disease Team Research I Mark Humayun Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $18,904,916
Shared Labs Andrew McMahon USC Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research $3,411,861
Early Translational III Toshio Miki Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Tools and Technologies III Toshio Miki Development of a clinical-grade extracorporeal liver support system using human induced pluripotent stem cell-derived hepatic cells $1,257,011
Quest - Discovery Stage Research Projects Neil Segil A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs $741,574
COMPASS Training Grant Senta Georgia USC COMPASS: Guiding Undergraduates to Careers in Regenerative Medicine $2,899,999
SEED Grant David Hinton Therapeutic potential of Retinal Pigment Epithelial cell lines derived from hES cells for retinal degeneration. $651,607
Tools and Technologies I Pin Wang Development of Baculoviral Vectors for Gene Editing of Human Stem Cells $945,604
Creativity Awards Roberta Brinton CIRM STAR High School Summer Research and Creativity Program $271,160
Tools and Technologies III Paula Cannon Site-specific gene editing in hematopoietic stem cells as an anti-HIV therapy $1,495,665
Therapeutic Translational Research Projects Mark Humayun PRPE-SF, polarized hESC-derived RPE Soluble Factors, as a Therapy for Early Stage Dry Age-related Macular Degeneration $3,733,556
Alpha Stem Cell Clinics Network Expansion Thomas Buchanan Alpha Clinic Network Expansion for Cell and Gene Therapies $7,999,983
SEED Grant Peter Laird Screening for Oncogenic Epigenetic Alterations in Human ES Cells $647,431
Transplantation Immunology Terrence Town Role of HLA in neural stem cell rejection using humanized mice $353,249
Research Leadership Andrew McMahon Repair and regeneration of the nephron $5,672,206
Tools and Technologies III Qilong Ying Embryonic stem cell-based generation of rat models for assessing human cellular therapies $1,326,979
Discovery Research Projects Justin Ichida Development of a novel PIKFYVE kinase inhibitor for the treatment of COVID-19 $140,067
SEED Grant Qilong Ying Self-renewal of human embryonic stem cells $621,421
New Faculty I Mohammad Pashmforoush Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors $2,816,578
Disease Team Therapy Development III Mark Humayun Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration $16,339,827
Therapeutic Translational Research Projects Denis Evseenko Pluripotent stem cell-derived chondrocytes for articular cartilage repair $2,503,104
Discovery Research Projects PREET Chaudhary Chimeric Antigen Receptor Targeting Spike Glycoprotein of SARS-cov2 $248,125
SEED Grant Wange Lu Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling $624,000
New Faculty I Songtao Shi Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells $3,242,651
Major Facilities Chrysostomos Nikias Broad CIRM Facility at USC $26,972,500
Conference Kathy Rich The Stem Cell Niche in Development and Regeneration $7,476
Quest - Discovery Stage Research Projects Justin Ichida Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS $222,300
New Faculty II Gage DeKoeyer Crump Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw $2,247,403
Research Training II Robert Maxson CIRM Stem Cell Biology Training Program $5,827,817
Disease Team Planning David Woodley Clinical Regenerative Wound Healing With Stem Cells $33,626
Conference Qing Liu-Michael USC/UCSF/UCLA Tri-Institutional Stem Cell Retreat $5,000
Conference II Justin Ichida The 7th Annual California ALS research network and PAC10 meeting $10,830
Research Training Grant Gage DeKoeyer Crump Training Program Bridging Stem Cell Research with Clinical Applications in Regenerative Medicine $5,000,000
Basic Biology I Wange Lu Defining the molecular mechanisms of somatic cell reprogramming $1,365,580
New Faculty II Qilong Ying Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation $2,261,174
Disease Team Therapy Planning I Roberta Brinton A CIRM Disease Team to Develop Allopregnanolone for Prevention and Treatment of Alzheimer's Disease $107,961
Disease Team Planning Mark Humayun Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $3,088
Inception - Discovery Stage Research Projects Biju Thomas A Novel Tissue Engineering Technique to Repair Degenerated Retina $215,133
Late Stage Preclinical Projects Frank Petrigliano Plurocart: a novel stem cell-based implant for articular cartilage restoration $5,999,782
Basic Biology I Martin Pera The stem cell microenvironment in the maintenance of pluripotency and reprogramming $1,325,723
New Cell Lines Martin Pera New Technology for the Derivation of Human Pluripotent Stem Cell Lines for Clinical Use $1,266,134
Training Grant I-1 Robert Maxson CIRM Stem Cell Biology Training Grant $2,332,431
Shared Labs Martin Pera USC Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research $1,724,015
Total:
$142,067,204.00
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