All CIRM Grants

Search Filters »

Institution Researcher name Grant Type Grant Title Award Value
Replay Holdings, Inc Anthony Conway Therapeutic Translational Research Projects Hypoimmunogenic iPSC-derived TCR-NK cells for oncology $4,107,571
AcuraStem Inc. Mr. Samuel V. Alworth MS, MBA Therapeutic Translational Research Projects Development of AS-241, an UNC13A Targeting Antisense Oligonucleotide (ASO) Treatment for ALS, for IND-enabling Studies $4,012,325
Axent Biosciences Inc. Abhay Joshi Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for Treatment of Guanidinoacetate Methyltransferase Deficiency-Translating In Vivo Proof of Concept to Support a Pre-IND $5,145,825
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic Therapy for Treatment of Geographic Atrophy $3,998,930
University of California, San Francisco Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
Siren Biotechnology, Inc. Dr. Nicole K Paulk Therapeutic Translational Research Projects Development of an AAV gene therapy immunotherapy for the treatment of glioblastoma $3,997,919
Cedars-Sinai Medical Center Dr. Ahmed Gamal Ibrahim Therapeutic Translational Research Projects Noncoding RNA drug TY1 as a therapeutic candidate for scleroderma and systemic sclerosis $2,590,224
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, Los Angeles Dr. Donald B Kohn Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Editing for X-linked Agammaglobulinemia (XLA) $4,309,973
University of California, San Diego Dr. Eric D. Adler MD Therapeutic Translational Research Projects Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
University of California, Los Angeles Dr. Gerald Lipshutz DDS, MD, MS Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504
City of Hope, Beckman Research Institute Dr Michael A. Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
University of California, Los Angeles Anthony J Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Wiskott Aldrich Syndrome $3,999,899
BrainXell Therapeutics Dr. Emmanuel E Baetge Therapeutic Translational Research Projects Development of Autologous Cell Replacement Therapy for Parkinson’s Disease: Path to Personalized Treatment $3,841,110
University of California, Los Angeles Dr. Sophie X Deng Therapeutic Translational Research Projects Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276
University of California, Los Angeles Dr. Scott G Kitchen Therapeutic Translational Research Projects Hematopoietic Stem/Progenitor Cell-Based Chimeric Antigen Receptor Gene Therapy for HIV Infection $6,140,723
Rejuvenation Technologies, Inc. John Ramunas Therapeutic Translational Research Projects Telomerase mRNA for short telomere related pulmonary fibrosis $3,984,942
University of Southern California Dr. Rongfu Wang Therapeutic Translational Research Projects Novel T cell receptor-STEM T cell immunotherapy in lung cancer $5,689,540
Stanford University Walter Park Therapeutic Translational Research Projects Enhanced Autologous Pancreatic Islet Transplantation and Survival for Diabetes Mellitus Therapy $6,054,165
VxBiosciences inc. Dr. Christina Chuong Therapeutic Translational Research Projects Escape-Resistant Oligonucleotide Therapy (ONT) for Cytomegalovirus (CMV) Disease in Hematopoietic Stem-Cell and Solid-Organ Transplant Patients $3,977,180
City of Hope, Beckman Research Institute Dr Jianhua Yu Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
Mahzi Therapeutics Dr. Allyson Berent Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Pitt Hopkins Syndrome (PHS) – Translating from Animal Proof of Concept to Support Pre-IND Meeting $3,800,760
University of California, Davis Dr. William J Murphy Therapeutic Translational Research Projects Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector $3,869,061
University of California, San Diego Stephanie Cherqui Therapeutic Translational Research Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
University of Southern California Preet M Chaudhary Therapeutic Translational Research Projects Next generation affinity-tuned CAR for prostate cancer $5,805,144
University of California, Los Angeles Dr. Donald B. Kohn Therapeutic Translational Research Projects Autologous MPO Knock-Out Hematopoietic Stem and Progenitor Cells for Pulmonary Arterial Hypertension $4,751,297
Ray Therapeutics, INC Paul Bresge Therapeutic Translational Research Projects Optogenetic therapy for treating retinitis pigmentosa and other inherited retinal diseases $3,999,553
University of California, Irvine Dr. Aileen J Anderson Therapeutic Translational Research Projects A human neural stem cell therapeutic candidate for the treatment of chronic cervical spinal cord injury $4,950,024
University of California, San Francisco Arun P Wiita Therapeutic Translational Research Projects CD72 nanoCARs for the treatment of refractory pediatric B-cell acute lymphoblastic leukemia $3,330,801
MyoGene Bio LLC Dr Courtney Young Therapeutic Translational Research Projects Development of MyoDys45-55, a gene editing therapy for Duchenne muscular dystrophy $3,400,000
Immusoft Corporation Dr Robert Hayes Therapeutic Translational Research Projects MPS II: Plasma cell delivery of iduronate sulfatase $3,994,676
Regencor, Inc. PILAR RUIZ-LOZANO Therapeutic Translational Research Projects IND-enabling Studies of Wearable Evolve-FSTL1 for Cardiac Regeneration after MI $3,923,191
University of California, San Francisco Dr. Hideho Okada Therapeutic Translational Research Projects Development of novel synNotch CART cell therapy in patients with recurrent EGFRvIII+ glioblastoma $4,531,536
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for IPEX Syndrome $3,551,332
University of California, Los Angeles Dr. Arjun Deb Therapeutic Translational Research Projects Targeting stromal progenitors to prevent the development of heart failure $4,714,824
Palo Alto Veterans Institute for Research Irene Lorenzo Llorente Therapeutic Translational Research Projects Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $5,149,913
University of California, Los Angeles Dr. Irene L. Llorente Therapeutic Translational Research Projects Clinical Translation of Allogenic Regenerative Cell Therapy for White Matter Stroke and Vascular Dementia $707,754
Juvena Therapeutics Inc. Jeremy D O’Connell Therapeutic Translational Research Projects Clinical Translation of hESC-derived protein therapy that positively regulates the regenerative capacity of post-natal muscle for treating DM1  $3,906,376
University of California, Los Angeles Cristina Puig Saus Therapeutic Translational Research Projects CAR-Tnm cell therapy for melanoma targeting TYRP-1 $5,904,462
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma $5,281,199
University of California, San Francisco Dr. Hideho Okada Therapeutic Translational Research Projects Development of novel synNotch CART cell therapy in patients with recurrent EGFRvIII+ glioblastoma $525,000
Sanford Burnham Prebys Medical Discovery Institute Dr. Evan Y. Snyder Therapeutic Translational Research Projects Human Neural Stem Cells (hNSCs) for neuroprotection in perinatal hypoxic-ischemic brain injury (HII)-Pre-IND-enabling Studies $4,963,684
Neurona Therapeutics Dr. Cory R Nicholas Therapeutic Translational Research Projects Development of a human stem cell-derived inhibitory neuron therapeutic for the treatment of chronic focal epilepsy $4,848,505
University of California, San Diego Mark H Tuszynski Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Neural Stem Cells for Severe Spinal Cord Injury (SCI) $6,235,897
University of California, Los Angeles Yvonne Y. Chen Therapeutic Translational Research Projects BCMA/CS1 Bispecific CAR-T Cell Therapy to Prevent Antigen Escape in Multiple Myeloma $3,176,805
University of California, Irvine Dr. Brian J. Cummings Therapeutic Translational Research Projects An optimized human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) $4,804,737
City of Hope, Beckman Research Institute Prof. Karen S Aboody M.D. Therapeutic Translational Research Projects Neural Stem cell-mediated oncolytic immunotherapy for ovarian cancer $2,873,262