Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
A dynamic interplay of enhancer elements regulates Klf4 expression in naive pluripotency. 2017 Genes Dev
A Hyper-Crosslinked Carbohydrate Polymer Scaffold Facilitates Lineage Commitment and Maintains a Reserve Pool of Proliferating Cardiovascular Progenitors. 2017 Transplant Direct
A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations. 2017 Elife
A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism. 2017 Alzheimers Res Ther
A Novel Hybrid Compound LLP2A-Ale Both Prevented and Rescued the Osteoporotic Phenotype in a Mouse Model of Glucocorticoid-Induced Osteoporosis. 2017 Calcif Tissue Int
A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. 2017 Biotechnol Bioeng
A post-translational modification switch controls coactivator function of histone methyltransferases G9a and GLP. 2017 EMBO Rep
A Rationally Designed, General Strategy for Membrane Orientation of Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes. 2017 ACS Chem Biol
A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment. 2017 Biomaterials
A small molecule screen to identify regulators of let-7 targets. 2017 Sci Rep
Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. 2017 Aging Cell
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. 2017 Dev Cell
An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. 2017 Stem Cell Reports
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. 2017 Front Physiol
Anodization of magnesium for biomedical applications – Processing, characterization, degradation and cytocompatibility. 2017 Acta Biomater
Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. 2017 Stem Cells Int
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). 2017 Proc Natl Acad Sci U S A
Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network. 2017 Proc Natl Acad Sci U S A
Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. 2017 Biomaterials
Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss. 2017 Nat Commun
Bioreactor culture duration of engineered constructs influences bone formation by mesenchymal stem cells. 2017 Biomaterials
BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities. 2017 Elife
Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas. 2017 Stem Cells
CAMK2gamma antagonizes mTORC1 activation during hepatocarcinogenesis. 2017 Oncogene
Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. 2017 Cell Stem Cell
Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells. 2017 Stem Cell Res Ther
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells. 2017 Circ Res
Cell-mediated enzyme prodrug cancer therapies. 2017 Adv Drug Deliv Rev
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. 2017 Cell Rep
Characterization of the Corneal Subbasal Nerve Plexus in Limbal Stem Cell Deficiency. 2017 Cornea
Clinical translation of bioartificial liver support systems with human pluripotent stem cell-derived hepatic cells. 2017 World J Gastroenterol
Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells. 2017 Tissue Eng Part C Methods
Comparison of Non-Coding RNAs in Exosomes and Functional Efficacy of Human Embryonic Stem Cell- versus Induced Pluripotent Stem Cell-Derived Cardiomyocytes. 2017 Stem Cells
Concise Review: Paracrine Functions of Vascular Niche Cells in Regulating Hematopoietic Stem Cell Fate. 2017 Stem Cells Transl Med
Continuous Optical 3D Printing of Green Aliphatic Polyurethanes. 2017 ACS Appl Mater Interfaces
Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness. 2017 Biomaterials
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. 2017 Nat Cell Biol
Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. 2017 Adv Healthc Mater
Correlation between the existence of the palisades of Vogt and limbal epithelial thickness in limbal stem cell deficiency. 2017 Clin Exp Ophthalmol
Created of Warm Blood and Nerves: Restoring an Enteric Nervous System in Organoids. 2017 Cell Stem Cell
Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy. 2017 J Neuromuscul Dis
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. 2017 Sci Rep
CTCF and cohesin regulate chromatin loop stability with distinct dynamics. 2017 Elife
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. 2017 Science
Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System. 2017 Stem Cell Reports
Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair. 2017 Circulation
Dense Bicoid hubs accentuate binding along the morphogen gradient. 2017 Genes Dev
Depletion of Tcf3 and Lef1 maintains mouse embryonic stem cell self-renewal. 2017 Biol Open
Detection of Pentosidine Cross-Links in Cell-Secreted Decellularized Matrices Using Time Resolved Fluorescence Spectroscopy. 2017 ACS Biomater Sci Eng
Development of Mural Cells: From In Vivo Understanding to In Vitro Recapitulation. 2017 Stem Cells Dev