All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
IQVIA, Inc. Peter Robinson Accelerating Center An Accelerating Center designed to expedite the development and delivery of high quality stem cell therapies to patients $11,772,453
University of California, San Diego Catriona Jamieson Conference – The 2016 Alpha Stem Cell Clinic Annual Symposium UCSD Division of Regenerative Medicine and CIRM Alpha Clinics Network Symposium $37,778
Mosaic Event Management, Inc. Ron Johnson Conference – Manage The 2016 Bridges And SPARK Annual Meetings 2016 CIRM Bridges & SPARK Meetings $205,388
Palo Alto Veterans Institute for Research Irene Lorenzo Llorente Quest – Discovery Stage Research Projects Inhibitory interneurons derived from human induced pluripotent stem cells to treat stroke $2,140,122
Novoglia, Inc. Dr. Sunil Gandhi Ph.D Quest – Discovery Stage Research Projects Gene-corrected human microglia for the treatment of adult onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) $1,417,948
University of California, San Francisco Faranak Fattahi Quest – Discovery Stage Research Projects Drug discovery for gastrointestinal motility disorders using hPSC-derived enteric ganglioids $1,954,367
University of Southern California Dr. Justin K Ichida Quest – Discovery Stage Research Projects Development of a VAV2 antisense oligonucleotide (ASO) treatment for ALS $2,072,560
Cedars-Sinai Medical Center Dr. Ritchie Ho Quest – Discovery Stage Research Projects C9orf72 repeat expansion-tuned allelic suppression by CRISPRi as an ALS therapy $2,274,768
University of California, Davis Ricardo Anibal Maselli MD Quest – Discovery Stage Research Projects Treatment of Myasthenic Syndrome due to Choline Acetyltransferase Deficiency Using AAV9-mediated Gene Therapy $1,500,000
Adverum Biotechnologies Cameron Keast Baker Quest – Discovery Stage Research Projects Development of an Optogenetic Vision Restoration Gene Therapy Using an Engineered Form of Melanopsin $1,150,820
Stanford University Dr. Robert Negrin MD Quest – Discovery Stage Research Projects Orthogonal IL2 Receptor Transduced Regulatory T Cells for Clinical Application $1,920,652
University of California, San Francisco Michael Wilson Quest – Discovery Stage Research Projects A First-in-Class Treatment for Progressive Multifocal Leukoencephalopathy Via Multimodal Immune System Engineering $2,182,396
Stanford University Dr. Michael F Clarke Quest – Discovery Stage Research Projects Developing a breast cancer stem cell drug $2,053,727
Cedars-Sinai Medical Center Dr. Ke Liao Quest – Discovery Stage Research Projects RNA-based therapeutics to augment regulatory T cells: a novel approach to treat myocarditis $2,264,509
University of Southern California Linda Sher Quest – Discovery Stage Research Projects Assessing the Functional, Immunologic and Microbiologic Characteristics of Human Livers Created in Chimeric Pigs $2,736,590
City of Hope, Beckman Research Institute Dr Jianhua Yu Quest – Discovery Stage Research Projects Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $2,263,500
Vertuis Bio, Inc. Lukas Bachmann Quest – Discovery Stage Research Projects Expanded Capacity AAV Retinal Gene Therapy Enabled by Efficient RNA-Joining Technology $0
Gladstone Institutes, J. David Lyandysha Viktorovna Zholudeva Quest – Discovery Stage Research Projects Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury $2,942,198
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
University of California, Los Angeles Dr. Richard Joseph Pietras Quest – Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
Greenstone Biosciences, Inc. Paul D Pang Quest – Discovery Stage Research Projects Drug Discovery for Duchenne Muscular Dystrophy Using Patient-Derived Human iPSCs $675,000
University of California, Berkeley Mr. Fyodor Urnov Quest – Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
University of California, Davis Aijun Wang PhD Quest – Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
Rubedo Life Sciences Inc. Marco Quarta Quest – Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Los Angeles Dr. Gerald Lipshutz Quest – Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
University of California, Los Angeles Frank Pajonk Quest – Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
Cedars-Sinai Medical Center Dmitriy Sheyn Quest – Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr. Michelina Iacovino Quest – Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
University of California, Berkeley 5106433559 Kevin E. Healy Quest – Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
BrainXell Therapeutics Matthew Goodus Quest – Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, San Diego Professor Alysson R Muotri Quest – Discovery Stage Research Projects A treatment for Rett syndrome using glial-restricted neural progenitor cells $1,402,240
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Modified RNA-Based Gene Therapy for Cardiac Regeneration Through Cardiomyocyte Proliferation $1,565,784
The Scintillon Institute Brian Lawson Quest – Discovery Stage Research Projects An hematopoietic stem-cell-based approach to treat HIV employing CAR T cells and anti-HIV broadly neutralizing antibodies. $1,143,600
University of California, Irvine Dr. Michael Demetriou Quest – Discovery Stage Research Projects CAR T cells targeting abnormal N-glycans for the treatment of refractory/metastatic solid cancers $1,414,800
University of California, Los Angeles Dr. Lili Yang Quest – Discovery Stage Research Projects Combating Ovarian Cancer Using Stem Cell-Engineered Off-The-Shelf CAR-iNKT Cells $1,404,000
Minutia, Inc. Katy Digovich Quest – Discovery Stage Research Projects Bioengineering human stem cell-derived beta cell organoids to monitor cell health in real time and improve therapeutic outcomes in patients $1,198,550
Nanotools Bioscience Dr. Alex Savtchenko PhD Quest – Discovery Stage Research Projects Enabling non-genetic activity-driven maturation of iPSC-derived neurons $675,000
University of California, Los Angeles Dr. Xian-Jie Yang Quest – Discovery Stage Research Projects Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
University of California, San Diego Dr. Joseph G. Gleeson Quest – Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
Scripps Research Institute Stuart A Lipton Quest – Discovery Stage Research Projects Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG) $1,658,123
University of California, Los Angeles Dr Dinesh S Rao Quest – Discovery Stage Research Projects Novel methods to eliminate cancer stem cells $1,384,347
University of California, San Diego Dr. Michael Karin Quest – Discovery Stage Research Projects Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
Cedars-Sinai Medical Center Dr. Robert Barrett Quest – Discovery Stage Research Projects A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease $776,340
Scripps Research Institute Dr Michael J Bollong Quest – Discovery Stage Research Projects Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS) $1,244,160
University of California, Davis Dr. Kyle D Fink PhD Quest – Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,429,378
University of California, Los Angeles Dr. Caroline Y. Kuo Quest – Discovery Stage Research Projects Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232
University of California, Los Angeles Dr. Donald B. Kohn Quest – Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
Stanford University Dr. Judith A Shizuru Quest – Discovery Stage Research Projects Targeted Immunotherapy-Based Blood Stem Cell Transplantation $1,341,910
Tenaya Therapeutics, Inc. Timothy Hoey Quest – Discovery Stage Research Projects Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure $1,017,000
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