Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing. 2012 Cell Cycle
Maternal Cdx2 is dispensable for mouse development. 2012 Development
Maternal microchimerism in patients with biliary atresia: Implications for allograft tolerance. 2012 Chimerism
Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells. 2012 Nat Protoc
Mechanisms of telomere loss and their consequences for chromosome instability. 2012 Front Oncol
Mediator and SAGA Have Distinct Roles in Pol II Preinitiation Complex Assembly and Function. 2012 Cell Rep
Mesenchymal stromal cell-based treatment of jaw osteoradionecrosis in Swine. 2012 Cell Transplant
Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis. 2012 Cell Stem Cell
Mesodermal Pten inactivation leads to alveolar capillary dysplasia-like phenotype. 2012 J Clin Invest
Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal. 2012 Cell Stem Cell
MicroRNA profiling predicts a variance in the proliferative potential of cardiac progenitor cells derived from neonatal and adult murine hearts. 2012 J Mol Cell Cardiol
microRNAs as novel regulators of stem cell pluripotency and somatic cell reprogramming. 2012 Bioessays
Mineralized Synthetic Matrices as an Instructive Microenvironment for Osteogenic Differentiation of Human Mesenchymal Stem Cells. 2012 Macromol Biosci
miR-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting VEGF Signaling. 2012 Circ Res
miR-125b Promotes Early Germ Layer Specification through Lin28/let-7d and Preferential Differentiation of Mesoderm in Human Embryonic Stem Cells. 2012 PLoS One
Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans. 2012 Proc Natl Acad Sci U S A
Mixed results for bone marrow-derived cell therapy for ischemic heart disease. 2012 JAMA
Modeling brain disease in a dish: really? 2012 Cell Stem Cell
Modeling neurodevelopmental disorders using human neurons. 2012 Curr Opin Neurobiol
Modeling Parkinson’s disease using induced pluripotent stem cells. 2012 Curr Neurol Neurosci Rep
Modeling psychiatric disorders at the cellular and network levels. 2012 Mol Psychiatry
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. 2012 Am J Physiol Lung Cell Mol Physiol
Molecular roadblocks for cellular reprogramming. 2012 Mol Cell
mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination. 2012 Genes Dev
Multifunctional materials through modular protein engineering. 2012 Adv Mater
N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells. 2012 PLoS One
NELL-1 Injection Maintains Long Bone Quantity and Quality in an Ovariectomy-Induced Osteoporotic Senile Rat Model. 2012 Tissue Eng Part A
NELL-1 promotes cell adhesion and differentiation via Integrinbeta1. 2012 J Cell Biochem
Neural progenitor cells regulate microglia functions and activity. 2012 Nat Neurosci
Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma. 2012 Gene Ther
Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. 2012 J Cell Biol
Non-exposed bisphosphonate-related osteonecrosis of the jaw: a critical assessment of current definition, staging, and treatment guidelines. 2012 Oral Dis
NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches. 2012 PLoS One
Novel Pathways to Erythropoiesis Induced by Dimerization of Intracellular cMpl in Human Hematopoietic Progenitors. 2012 Stem Cells
Numb Expression and Asymmetric Versus Symmetric Cell Division in Distal Embryonic Lung Epithelium. 2012 J Histochem Cytochem
Olig1 function is required for remyelination potential of transplanted neural progenitor cells in a model of viral-induced demyelination. 2012 Exp Neurol
Partitioning the heart: mechanisms of cardiac septation and valve development. 2012 Development
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. 2012 Sci Transl Med
PEDF Is a Novel Oligodendrogenic Morphogen Acting on the Adult SVZ and Corpus Callosum. 2012 J Neurosci
Perivascular cells for regenerative medicine. 2012 J Cell Mol Med
Perivascular stem cells: a prospectively purified mesenchymal stem cell population for bone tissue engineering. 2012 Stem Cells Transl Med
Pharmacological chaperoning of nicotinic acetylcholine receptors reduces the endoplasmic reticulum stress response. 2012 Mol Pharmacol
Phasor Fluorescence Lifetime Microscopy of Free and Protein-Bound NADH Reveals Neural Stem Cell Differentiation Potential. 2012 PLoS One
Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche. 2012 Cell Rep
Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells. 2012 Proc Natl Acad Sci U S A
Pluripotency in 3D: genome organization in pluripotent cells. 2012 Curr Opin Cell Biol
Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. 2012 PLoS Genet
Potent low toxicity inhibition of human melanogenesis by novel indole-containing octapeptides. 2012 Biochim Biophys Acta
PPARgamma activation prevents impairments in spatial memory and neurogenesis following transient illness. 2012 Brain Behav Immun
Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells. 2012 Nature
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