University of California, Irvine

Total Awards: 
47
Award Value: 
$114,348,227
Major Facility Name: 
Sue and Bill Gross Stem Cell Research Center
Institution type: 
Not for profit

Short Name: 
UC Irvine

Awards to the Institution

Program Investigator Award Title Award Value
SEED Grant Grant MacGregor Production of Oocytes from Human ES Cells $385,466
Quest - Discovery Stage Research Projects Leslie Thompson hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Shared Labs Peter Donovan The University of California: Irvine Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $3,072,500
Basic Biology II Marian Waterman TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,259,879
Disease Team Planning Leslie Thompson Huntington's Disease Team $41,953
SEED Grant Vincent Procaccio Mitochondrial Dysfunction in Embryonic Stem Cells $245,582
Conference II Leslie Thompson Stem Cells for Huntington’s Disease (HD) International (SC4HDI) Conference $36,133
Disease Team Therapy Development - Research Henry Klassen Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
SEED Grant Michelle Khine Micro Platform for Controlled Cardiac Myocyte Differentiation $156,426
Conference Michelle Khine UC Systemwide Bioengineering Symposium $7,525
Tools and Technologies I Lisa Flanagan Novel Separation of Stem Cell Subpopulations $861,122
Early Translational II Brian Cummings Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
Shared Labs Peter Donovan The University of California: Irvine Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $2,107,376
New Faculty II Edwin Monuki Mechanisms in Choroid Plexus Epithelial Development $2,793,395
Therapeutic Translational Research Projects Magdalene Seiler Morphological and functional integration of stem cell derived retina organoid sheets into degenerating retina models $4,769,039
Early Translational IV Magdalene Seiler Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs) $3,998,948
SEED Grant Kyoko Yokomori Derivation and characterization of human ES cells from FSHD embryos $607,200
Conference Peter Donovan Systems Biology of Stem Cells $25,000
Tools and Technologies I Orhan NALCIOGLU A MULTI-MODALITY MOLECULAR IMAGING SYSTEM (MRSPECT) FOR IN VIVO STEM CELL TRACKING $719,798
Early Translational II Leslie Thompson A hESc-based Development Candidate for Huntington's Disease $3,955,038
Tools and Technologies III Mathew Blurton-Jones Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease. $1,147,596
Comprehensive Grant Peter Donovan Improved hES Cell Growth and Differentiation $2,381,713
Basic Biology V Lisa Flanagan Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108
SEED Grant Thomas Lane Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $368,081
Patent Assistance Fund Awards Ronnie Hanecak CIRM Patent Assistance Fund Application - UCI $0
New Faculty I Andrew Putnam A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells $395,764
Early Translational II Henry Klassen Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768
Preclinical Development Awards Leslie Thompson A hNSC Development Candidate for Huntington’s Disease $4,951,623
Comprehensive Grant Douglas Wallace The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
Basic Biology V Peter Donovan Non-invasive live imaging of stem cell signature metabolic states $516,366
SEED Grant Brian Cummings The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $595,345
Inception - Discovery Stage Research Projects Janet Baulch An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
Research Training II Peter Donovan UCI-CIRM Research Training Program II $6,067,550
Early Translational II leif Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,527,011
Conference II Sidney Golub Human Research In Times of Controversy: From Stem Cells To Fetal Tissue $13,562
Comprehensive Grant Hans Keirstead hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445
Major Facilities Michael Drake UC Irvine CIRM Institute $27,156,000
SEED Grant Charles Limoli Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $593,242
Quest - Discovery Stage Research Projects Brian Cummings Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
Training Grant I-1 Peter Bryant Stem Cell Research Training Grant $1,935,487
New Cell Lines Leslie Thompson New Cell Lines for Huntington's Disease $1,302,526
Conference II LESLIE Thompson HD-CARE INAUGURAL SYMPOSIUM $1,500
Early Translational I Frank LaFerla Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
Basic Biology II Aileen Anderson Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194
Disease Team Planning Henry Klassen Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $23,537
SEED Grant Frank LaFerla Development of human ES cell lines as a model system for Alzheimer disease drug discovery $473,963
Quest - Discovery Stage Research Projects Aileen Anderson Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury. $1,575,613
Early Translational III Craig Walsh Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,535,005
Total:
$114,348,227.00
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