University of California, Irvine

Total Awards: 
Award Value: 
Major Facility Name: 
Sue and Bill Gross Stem Cell Research Center
Institution type: 
Not for profit

Short Name: 
UC Irvine

Awards to the Institution

Program Investigator Award Title Award Value
Patent Assistance Fund Awards Ronnie Hanecak CIRM Patent Assistance Fund Application - UCI $46,155
Conference – The 2020 Grantee Meeting Daniela Bota 2020 CIRM Grantee Meeting $176,762
Quest - Discovery Stage Research Projects Mathew Blurton-Jones Transplantation of genetically corrected iPSC-microglia for the treatment of Sanfilippo Syndrome (MPSIIIA) $1,083,379
Early Translational II Brian Cummings Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
SEED Grant Thomas Lane Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $368,081
Comprehensive Grant Hans Keirstead hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445
Early Translational III Craig Walsh Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,535,005
Shared Labs Peter Donovan The University of California: Irvine Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $2,107,376
Inception - Discovery Stage Research Projects Janet Baulch An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
Progression Award - Discovery Stage Research Projects Brian Cummings Human neural stem cell (hNSC) derived exosomes vs CSC14 hNSCs for the treatment of traumatic brain injury (TBI) $202,667
Quest - Discovery Stage Research Projects Michael Demetriou CAR T cells targeting abnormal N-glycans for the treatment of refractory/metastatic solid cancers $1,414,800
Early Translational II Leslie Thompson A hESc-based Development Candidate for Huntington's Disease $3,955,038
SEED Grant Brian Cummings The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $595,345
Early Translational I Frank LaFerla Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
Disease Team Therapy Development - Research Henry Klassen Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825
Tools and Technologies III Mathew Blurton-Jones Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease. $1,147,596
Quest - Discovery Stage Research Projects Brian Cummings Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
Quest - Discovery Stage Research Projects Mathew Blurton-Jones Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP) $214,668
COMPASS Training Grant Brian Cummings Research Mentorship Program in Regenerative Medicine Careers for a Diverse Undergraduate Student Body $2,729,900
Early Translational II Henry Klassen Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768
SEED Grant Charles Limoli Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $593,242
Shared Labs Peter Donovan The University of California: Irvine Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $3,072,500
Early Translational IV Magdalene Seiler Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs) $3,998,948
Preclinical Development Awards Leslie Thompson A hNSC Development Candidate for Huntington’s Disease $4,951,623
Quest - Discovery Stage Research Projects Aileen Anderson Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury. $1,575,613
Quest - Discovery Stage Research Projects Robert Hunt Optimization of a human interneuron cell therapy for traumatic brain injury $250,000
Alpha Stem Cell Clinics Network Expansion Daniela Bota A hub and spoke community model to equitably deliver regenerative medicine therapies to diverse populations across four California counties $8,000,000
Early Translational II leif Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,527,011
SEED Grant Frank LaFerla Development of human ES cell lines as a model system for Alzheimer disease drug discovery $473,963
Tools and Technologies I Lisa Flanagan Novel Separation of Stem Cell Subpopulations $861,122
Basic Biology V Lisa Flanagan Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108
Conference II Sidney Golub Human Research In Times of Controversy: From Stem Cells To Fetal Tissue $13,562
Conference II Leslie Thompson Stem Cells for Huntington’s Disease (HD) International (SC4HDI) Conference $31,727
Quest - Discovery Stage Research Projects Munjal Acharya Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury $1,064,724
Conference II Mathew Blurton-Jones ALSP Community Conference: Insights and Potential of Cell-Based Therapies for the Treatment of Leukodystrophies $42,500
New Cell Lines Leslie Thompson New Cell Lines for Huntington's Disease $1,302,526
SEED Grant Vincent Procaccio Mitochondrial Dysfunction in Embryonic Stem Cells $245,582
Basic Biology V Peter Donovan Non-invasive live imaging of stem cell signature metabolic states $516,366
Therapeutic Translational Research Projects Magdalene Seiler Morphological and functional integration of stem cell derived retina organoid sheets into degenerating retina models $4,769,039
Research Training Grant Peter Donovan CIRM Scholars Comprehensive Research Training Program $5,000,000
Foundation - Discovery Stage Research Projects Brian Cummings Mapping the spatial and temporal responses of hESC-derived microglia to repeat mild closed head injury to identify therapeutic targets and mechanisms $1,555,140
SEED Grant Grant MacGregor Production of Oocytes from Human ES Cells $385,466
New Faculty II Edwin Monuki Mechanisms in Choroid Plexus Epithelial Development $2,793,395
New Faculty I Andrew Putnam A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells $395,764
Major Facilities Michael Drake UC Irvine CIRM Institute $27,156,000
Quest - Discovery Stage Research Projects Leslie Thompson hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Late Stage Preclinical Projects Leslie Thompson An hESC-derived hNSC Therapeutic for Huntington’s Disease $5,635,393
Therapeutic Translational Research Projects Aileen Anderson A human neural stem cell therapeutic candidate for the treatment of chronic cervical spinal cord injury $4,950,024
Foundation - Discovery Stage Research Projects Albert La Spada Role of ataxin-3 polyadenylation site selection in ALS neuron toxicity and disease pathogenesis $1,514,416
Basic Biology II Aileen Anderson Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194
SEED Grant Michelle Khine Micro Platform for Controlled Cardiac Myocyte Differentiation $156,426
Comprehensive Grant Peter Donovan Improved hES Cell Growth and Differentiation $2,381,713
Research Training II Peter Donovan UCI-CIRM Research Training Program II $6,067,550
Disease Team Planning Henry Klassen Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $23,537
Conference Michelle Khine UC Systemwide Bioengineering Symposium $7,525
Therapeutic Translational Research Projects Brian Cummings An optimized human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) $4,804,737
Conference II Olga Razorenova UCI Stem Cell Research Center 9th Annual Stem Cell Science Symposium $8,366
Late Stage Preclinical Projects Kyriacos Athanasiou Treatment of the TMJ disc complex $6,000,000
Basic Biology II Marian Waterman TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,259,879
SEED Grant Kyoko Yokomori Derivation and characterization of human ES cells from FSHD embryos $607,200
Comprehensive Grant Douglas Wallace The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
Training Grant I-1 Peter Bryant Stem Cell Research Training Grant $1,935,487
Disease Team Planning Leslie Thompson Huntington's Disease Team $41,953
Conference Peter Donovan Systems Biology of Stem Cells $25,000
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