Scripps Research Institute

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Awards to the Institution

Program Type	Investigator	Grant Title	Award Value
ReMIND – Discovery Stage ReMIND	Xin Jin	Translational epigenomics: dissecting cell type-specific function of neuropsychiatric risk genes in vivo	$11,376,314
ReMIND – Discovery Stage ReMIND	Stuart A Lipton	Multiomic Studies of Idiopathic Intellectual Disability and Autism Spectrum Disorder (ID/ASD)	$17,365,387
Foundation – Discovery Stage Research Projects	Giordano Lippi	A novel platform to rescue neurodevelopmental disorders caused by haploinsufficiency	$4,086,486
Foundation – Discovery Stage Research Projects	Xin Jin	Functional genomics to study cellular convergence across ASD risk genes in neurodevelopment	$1,575,001
Research Training Grant	Peter G. Schultz	Training Scholars in Regenerative Medicine and Stem Cell Research	$5,304,759
Discovery Research Projects	Stuart A Lipton	Repurposing Aminoadamantane Nitrate Compounds to Inhibit SARS-CoV-2 Viral Activity and to Protect the Brain from Viral-Related Damage	$150,000
Quest – Discovery Stage Research Projects	Stuart A Lipton	Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG)	$1,648,969
Quest – Discovery Stage Research Projects	Dr Michael J Bollong	Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS)	$1,244,160
Quest – Discovery Stage Research Projects	Luke L Lairson	Improving the efficacy and tolerability of clinically validated remyelination-inducing molecules using developable combinations of approved drugs	$1,554,126
Quest – Discovery Stage Research Projects	Stuart A Lipton	Drug Development for Autism Spectrum Disorder Using Human Patient iPSCs	$1,827,576
Quest – Discovery Stage Research Projects	Dr. Jeanne F Loring	Autologous cell therapy for Parkinson’s disease using iPSC-derived DA neurons	$2,299,786
Tools and Technologies III	Dr. Jeanne F Loring	User-friendly predictive molecular diagnostic assays for quality control of stem cell derivatives for transplantation and drug discovery	$1,728,390
Conference	Dr. Jeanne F Loring	World Stem Cell Summit	$30,000
Creativity Awards	James R Williamson	Stem Cell Summer Academy: Creating the Next Generation of Scientists	$205,122
Early Translational III	Peter G. Schultz	Targeting Stem Cells to Enhance Remyelination in the Treatment of Multiple Sclerosis	$2,559,333
Training Grant I-2	Peter G. Schultz	Training Grant I	$1,021,395
Research Training II	Dr. Ulrich Mueller	Training Stem Cell Researchers at the Chemistry-Biology Interface	$3,697,326
Basic Biology III	Dr. Joel M Gottesfeld	Triplet Repeat Instability in Human iPSCs	$1,705,494
Basic Biology III	Kristin Baldwin	Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing	$1,705,500
Early Translational II	Peter G. Schultz	Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis	$6,047,249
New Faculty I	Kristin Baldwin	Generating pluripotent cell lines from neurons.	$2,786,560
New Faculty I	Dr. Sheng Ding Dr.	Reprogramming of human somatic cells back to pluripotent embryonic stem cells	$1,393,876
Early Translational I	Dr. Martin Friedlander	Autologous Retinal Pigmented Epithelial Cells Derived from Induced Pluripotent Stem Cells for the Treatment of Atrophic Age Related Macular Degeneration	$5,806,321
Early Translational I	Dr. Jeanne F Loring	Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation	$5,830,771
Transplantation Immunology	Dr. Nicholas R.J. Gascoigne	Role of Innate Immunity in hematopoeitic stem cell-mediated allograft tolerance	$1,705,554
Transplantation Immunology	Dr. Jeanne F Loring	Thymus based tolerance to stem cell therapies	$1,108,921
Tools and Technologies I	Dr. Jeanne F Loring	The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells	$1,133,552
Tools and Technologies I	Dr. Carlos F. Barbas Dr.	Development of a novel technology for precise, efficient, and safe genetic modification of stem cells	$1,138,548
Shared Labs	Sheng Ding PhD	TSRI Center for hESC Research	$1,440,164
Shared Labs	Dr. Jeanne F Loring	TSRI Center for hESC Research	$3,725,070
New Cell Lines	Dr. Sheng Ding Dr.	Derivation of New ICM-stage hESCs	$936,973
SEED Grant	Peter G. Schultz	A Chemical Approach to Stem Cell Biology	$748,944
			Total: $94,887,626.01