Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

See our complete portfolio of awards below.

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Institution Researcher name Grant Type Grant Title Award Value
University of California, San Francisco Dr. Qizhi Tang PhD Quest – Discovery Stage Research Projects Genome editing of human Tregs to enable combinational tolerogenic therapy with T cell-targeted biologics for T1D $2,485,549
Palo Alto Veterans Institute for Research Dr. Jian Luo Quest – Discovery Stage Research Projects Human induced pluripotent stem cells-derived glial enriched progenitors for the treatment of mild traumatic brain injury $2,255,189
Palo Alto Veterans Institute for Research Irene Lorenzo Llorente Quest – Discovery Stage Research Projects Inhibitory interneurons derived from human induced pluripotent stem cells to treat stroke $2,140,122
University of California, San Francisco Faranak Fattahi Quest – Discovery Stage Research Projects Drug discovery for gastrointestinal motility disorders using hPSC-derived enteric ganglioids $1,954,367
University of Southern California Dr. Justin K Ichida Quest – Discovery Stage Research Projects Development of a VAV2 antisense oligonucleotide (ASO) treatment for ALS $2,072,560
Cedars-Sinai Medical Center Dr. Ritchie Ho Quest – Discovery Stage Research Projects C9orf72 repeat expansion-tuned allelic suppression by CRISPRi as an ALS therapy $2,274,768
University of California, Davis Ricardo Anibal Maselli MD Quest – Discovery Stage Research Projects Treatment of Myasthenic Syndrome due to Choline Acetyltransferase Deficiency Using AAV9-mediated Gene Therapy $1,500,000
Stanford University Dr. Robert Negrin MD Quest – Discovery Stage Research Projects Orthogonal IL2 Receptor Transduced Regulatory T Cells for Clinical Application $1,920,652
University of California, San Francisco Michael Wilson Quest – Discovery Stage Research Projects A First-in-Class Treatment for Progressive Multifocal Leukoencephalopathy Via Multimodal Immune System Engineering $2,182,396
Stanford University Dr. Michael F Clarke Quest – Discovery Stage Research Projects Developing a breast cancer stem cell drug $2,053,727
Cedars-Sinai Medical Center Dr. Ke Liao Quest – Discovery Stage Research Projects RNA-based therapeutics to augment regulatory T cells: a novel approach to treat myocarditis $2,264,509
University of Southern California Dr Linda Sher M.D. Quest – Discovery Stage Research Projects Assessing the Functional, Immunologic and Microbiologic Characteristics of Human Livers Created in Chimeric Pigs $2,736,590
University of California, Irvine Jianhua Yu Quest – Discovery Stage Research Projects Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $1,509,000
Gladstone Institutes, J. David Lyandysha Zholudeva Quest – Discovery Stage Research Projects Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury $2,942,198
University of California, Los Angeles Prof. Song Li Quest – Discovery Stage Research Projects Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
University of California, Los Angeles Dr. Richard Joseph Pietras Quest – Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
University of California, Berkeley Mr. Fyodor Urnov Quest – Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
University of California, Davis Aijun Wang PhD Quest – Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
Rubedo Life Sciences Inc. Marco Quarta Quest – Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Los Angeles Dr. Gerald Lipshutz Quest – Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
University of California, Los Angeles Frank Pajonk Quest – Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
Scripps Health Dr. Darryl D. D’Lima Quest – Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
Cedars-Sinai Medical Center Dmitriy Sheyn Quest – Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Dr. Michelina Iacovino PhD Quest – Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
University of California, Berkeley Kevin E. Healy Quest – Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
BrainXell Therapeutics, Inc. Matthew Goodus Quest – Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $1,687,500
CellFE Biotech Sewoon Han Tool Translational Research Projects Purpose built cell engineering for rapid manufacturing of stem-like cell therapies $934,750
University of California, Davis Aijun Wang PhD Medical Device Translational Research Projects Living Synthetic Vascular Grafts with Renewable Endothelium $3,082,579
Cedars-Sinai Medical Center Yuan Yuan Diagnostic Translational Research Projects A Rapid Clinical Digital Patient-derived Organoid to Guide Breast Cancer Treatment Decision $1,535,375
Stanford University Sergiu P Pasca Therapeutic Translational Research Projects A targeted antisense oligonucleotide therapeutic strategy for Timothy syndrome $5,596,629
University of California, Irvine Dr. Michael Demetriou Therapeutic Translational Research Projects GlyTR2 CAR T cell translation: safe pan-cancer killing via velcro-like density-dependent targeting of cancer glycans $4,581,144
University of California, San Francisco Gregory Maness Allen Therapeutic Translational Research Projects FM-IL2 CAR T cells for Pancreatic Cancer $5,644,776
Entos Pharmaceuticals John Lewis Therapeutic Translational Research Projects Lep001 – gene therapy for the treatment of congenital lipodystrophy $4,000,000
University of California, Los Angeles Roger Hollis Therapeutic Translational Research Projects Evaluation of an ex vivo lentiviral gene therapy for the treatment of Angelman syndrome $5,276,765
ReviR Therapeutics Dr Paul R August Therapeutic Translational Research Projects Genetic Therapy Targeting mHTT mRNA and Somatic Expansion to Treat Huntington’s Disease $4,618,687
University of Southern California David D. Tran Therapeutic Translational Research Projects A Novel Gene Therapy to Target Glioblastoma via Custom-Engineered Adenovirus-Associated Viral Vectors $5,927,454
Maro Bio Akanksha Chhabra Therapeutic Translational Research Projects A novel non-genotoxic antibody conditioning therapeutic to expand access to and safety of HSCT and CD34+ gene therapies $4,043,427
University of California, Los Angeles Dr. Donald B. Kohn Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $5,028,351
University of California, Los Angeles Dr. Lili Yang Therapeutic Translational Research Projects Combating Ovarian Cancer with Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy $5,601,600
Stanford University Natalia Gomez-Ospina Therapeutic Translational Research Projects Toward a Cure for Gaucher Disease Type 1: Autologous Transplantation of Genome Edited Hematopoietic Stem Cells $4,696,296
Axent Biosciences Inc. Rocio Sampayo Therapeutic Translational Research Projects A high quality, accessible cell therapy for Parkinson’s Disease produced in a scalable bioreactor system for 3D cell expansion and differentiation $3,999,241
University of California, Los Angeles Dr. Gerald Lipshutz Therapeutic Translational Research Projects Development of a Gene Therapy for Treatment of Guanidinoacetate Methyltransferase Deficiency-Translating In Vivo Proof of Concept to Support a Pre-IND $5,145,825
University of California, San Francisco Dr. Sarah Monica Knox Therapeutic Translational Research Projects Neurogenic hydrogel stimulation of stem cells to regenerate radiation-damaged salivary glands $2,312,021
University of California, San Diego Dr Karen Christman Therapeutic Translational Research Projects Pro-regenerative infusible ECM biomaterial for treating acute myocardial infarction $4,353,438
University of California, Los Angeles Zulema Romero Garcia Therapeutic Translational Research Projects Adenine Base Editing for Autologous Hematopoietic Stem Cell Gene Therapy of CD3δ SCID $5,966,928
University of California, Los Angeles Dr. Caroline Y. Kuo Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Editing for X-linked Agammaglobulinemia (XLA) $4,304,883
University of California, San Diego Dr. Eric D. Adler Therapeutic Translational Research Projects Ex Vivo Modified Hematopoietic Stem Cells to Treat Danon Disease $5,180,389
University of California, Los Angeles Dr. Gerald Lipshutz Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Arginase Deficiency – Translating from Proof of Concept to Support Pre-IND Meeting $5,266,504
City of Hope, Beckman Research Institute Dr Michael A. Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
University of California, Los Angeles Anthony J Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
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