Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Neonatal immune-tolerance in mice does not prevent xenograft rejection. 2014 Exp Neurol
Network biology: A compass for stem-cell differentiation. 2014 Nature
Neural stem cells genetically-modified to express neprilysin reduce pathology in Alzheimer transgenic models. 2014 Stem Cell Res Ther
Neural stem cells improve intracranial nanoparticle retention and tumor-selective distribution. 2014 Future Oncol
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. 2014 Science
Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. 2014 Development
Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. 2014 Stem Cells
Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model. 2014 Proc Natl Acad Sci U S A
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture. 2014 Nat Med
Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration. 2014 Nat Commun
p63 inhibits extravillous trophoblast migration and maintains cells in a cytotrophoblast stem cell-like state. 2014 Am J Pathol
Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization of Cardiac Cells. 2014 Methods Mol Biol
Persistent replicative stress alters polycomb phenotypes and tissue homeostasis in Drosophila melanogaster. 2014 Cell Rep
Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes. 2014 Cell Death Dis
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. 2014 Mol Psychiatry
Polyglutamine Disease Modeling: Epitope Based Screen for Homologous Recombination using CRISPR/Cas9 System. 2014 PLoS Curr
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. 2014 Nat Neurosci
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. 2014 Proc Natl Acad Sci U S A
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. 2014 Cell Rep
Potential for Cell Therapy in Parkinson’s Disease Using Genetically-Programmed Human Embryonic Stem Cell-Derived Neural Progenitor Cells. 2014 J Comp Neurol
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. 2014 Proc Natl Acad Sci U S A
Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development. 2014 J Dent Res
Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. 2014 Cell Stem Cell
Promoting remyelination: utilizing a viral model of demyelination to assess cell-based therapies. 2014 Expert Rev Neurother
Protein post-translational modifications and regulation of pluripotency in human stem cells. 2014 Cell Res
Ptch2 mediates the Shh response in Ptch1-/- cells. 2014 Development
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. 2014 Nat Immunol
Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. 2014 Nature
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia. 2014 Nat Genet
Rapid and Efficient Conversion of Integration-Free Human Induced Pluripotent Stem Cells to GMP-Grade Culture Conditions. 2014 PLoS One
Recombinase-Mediated Reprogramming and Dystrophin Gene Addition in mdx Mouse Induced Pluripotent Stem Cells. 2014 PLoS One
Regenerative medicine: is this the biggest change in surgery? 2014 Semin Pediatr Surg
Regulation of iPS Cell Induction by Wnt/beta-catenin Signaling. 2014 J Biol Chem
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. 2014 Nat Med
Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines. 2014 Stem Cells Transl Med
Reorganization of enhancer patterns in transition from naive to primed pluripotency. 2014 Cell Stem Cell
Replication of Mycobacterium tuberculosis in retinal pigment epithelium. 2014 JAMA Ophthalmol
Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. 2014 Nature
Reprogramming by lineage specifiers: blurring the lines between pluripotency and differentiation. 2014 Curr Opin Genet Dev
Reprogramming Human Retinal Pigmented Epithelial Cells to Neurons Using Recombinant Proteins. 2014 Stem Cells Transl Med
Research capacity. Enabling the genomic revolution in Africa. 2014 Science
ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. 2014 Stem Cells Transl Med
Role of astroglia in Down’s syndrome revealed by patient-derived human-induced pluripotent stem cells. 2014 Nat Commun
Role of BRCA1 in brain development. 2014 Proc Natl Acad Sci U S A
Roles of heat shock factor 1 in neuronal response to fetal environmental risks and its relevance to brain disorders. 2014 Neuron
Serine integrase chimeras with activity in E. coli and HeLa cells. 2014 Biol Open
Sexually dimorphic effect of in vitro fertilization (IVF) on adult mouse fat and liver metabolomes. 2014 Endocrinology
Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst. 2014 EMBO J
Signaling pathways in induced naive pluripotency. 2014 Curr Opin Genet Dev
Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed States of human pluripotent stem cells. 2014 Stem Cell Reports