Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Conversion of human fibroblasts into functional cardiomyocytes by small molecules. 2016 Science
Correction: Identification of Androgen Receptor Splice Variants in the Pten Deficient Murine Prostate Cancer Model. 2016 PLoS One
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. 2016 Nat Biotechnol
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. 2016 Cell Stem Cell
Culturing Human Pluripotent and Neural Stem Cells in an Enclosed Cell Culture System for Basic and Preclinical Research. 2016 J Vis Exp
Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. 2016 Cell Rep
Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation. 2016 Science
Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells. 2016 Curr Stem Cell Rep
Development of the Mammalian Kidney. 2016 Curr Top Dev Biol
Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. 2016 Development
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros. 2016 Nat Biotechnol
Direct 3D-printing of cell-laden constructs in microfluidic architectures. 2016 Lab Chip
Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq. 2016 Nature
Distal airway epithelial progenitor cells are radiosensitive to High-LET radiation. 2016 Sci Rep
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. 2016 Nat Commun
Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions. 2016 Cell Rep
Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. 2016 JCI Insight
Dysregulated endocardial TGFbeta signaling and mesenchymal transformation result in heart outflow tract septation failure. 2016 Dev Biol
Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury. 2016 Cell Transplant
Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies. 2016 Adv Drug Deliv Rev
Enhanced CLIP Uncovers IMP Protein-RNA Targets in Human Pluripotent Stem Cells Important for Cell Adhesion and Survival. 2016 Cell Rep
Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target. 2016 Brain
ERRgamma Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive beta Cells. 2016 Cell Metab
Evaluating Cell Processes, Quality, and Biomarkers in Pluripotent Stem Cells Using Video Bioinformatics. 2016 PLoS One
Existence of Normal Limbal Epithelium in Eyes With Clinical Signs of Total Limbal Stem Cell Deficiency. 2016 Cornea
Extensive migration of young neurons into the infant human frontal lobe. 2016 Science
From the Cover: Thirdhand Cigarette Smoke Causes Stress-Induced Mitochondrial Hyperfusion and Alters the Transcriptional Profile of Stem Cells. 2016 Toxicol Sci
Functional Human and Murine Tissue-Engineered Liver Is Generated From Adult Stem/Progenitor Cells. 2016 Stem Cells Transl Med
Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson’s Disease. 2016 Cell Stem Cell
Gene expression changes in the retina following subretinal injection of human neural progenitor cells into a rodent model for retinal degeneration. 2016 Mol Vis
Generation and Characterization of Patient-Specific Induced Pluripotent Stem Cell for Disease Modeling. 2016 Methods Mol Biol
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. 2016 Stem Cells
Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. 2016 J Assoc Res Otolaryngol
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. 2016 Nat Commun
Glycolytic Metabolism Plays a Functional Role in Regulating Human Pluripotent Stem Cell State. 2016 Cell Stem Cell
Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. 2016 Hum Mol Genet
Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy. 2016 Sci Transl Med
High-resolution imaging and computational analysis of haematopoietic cell dynamics in vivo. 2016 Nat Commun
High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies. 2016 Front Neurol
HIV-1-Specific Chimeric Antigen Receptors Based on Broadly Neutralizing Antibodies. 2016 J Virol
Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic. 2016 Tissue Eng Part A
Human Endometrial Fibroblasts Derived from Mesenchymal Progenitors Inherit Progesterone Resistance and Acquire an Inflammatory Phenotype in the Endometrial Niche in Endometriosis. 2016 Biol Reprod
Human Mesenchymal Stem Cells Genetically Engineered to Overexpress Brain-derived Neurotrophic Factor Improve Outcomes in Huntington’s disease Mouse Models. 2016 Mol Ther
Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. 2016 Proc Natl Acad Sci U S A
Hyaluronan as a therapeutic target in human diseases. 2016 Adv Drug Deliv Rev
Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. 2016 Matrix Biol
Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer. 2016 Cell Rep
Identifying gene expression modules that define human cell fates. 2016 Stem Cell Res
IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3. 2016 Hum Mol Genet
Immunosuppressive Treatment Can Alter Visual Performance in the RCS Rat. 2016 J Ocul Pharmacol Ther