All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
BrainXell Therapeutics Matthew Goodus Quest - Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, Berkeley Kevin Healy Quest - Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
Lundquist Institute for Biomedical Innovation at Harbor - UCLA Medical Center Michelina Iacovino Quest - Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
Cedars-Sinai Medical Center Dmitriy Sheyn Quest - Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Scripps Health Darryl D’Lima Quest - Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
University of California, Los Angeles Frank Pajonk Quest - Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
University of California, Los Angeles Gerald Lipshutz Quest - Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
Rubedo Life Sciences Inc. Marco Quarta Quest - Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
University of California, Davis Aijun Wang Quest - Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
University of California, Berkeley Fyodor Urnov Quest - Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
Greenstone Biosciences Nikesh Kotecha Quest - Discovery Stage Research Projects Drug Discovery for Duchenne Muscular Dystrophy Using Patient-Derived Human iPSCs $675,000
University of California, Los Angeles Richard Pietras Quest - Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
University of California, Los Angeles Song Li Quest - Discovery Stage Research Projects Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
Ossium Health Brian Johnstone Late Stage Preclinical Projects Development of OSSM-007, cryopreserved interferon-gamma primed allogeneic MSCs, for treatment of steroid refractory acute graft versus host disease $3,457,858
Gladstone Institutes, J. David Lyandysha Zholudeva Quest - Discovery Stage Research Projects Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury $2,942,198
Ryne Bio Howard Federoff Late Stage Preclinical Projects Allogeneic iPSC derived Dopaminergic Drug Product for Parkinson's disease $4,000,000
Vertuis Bio, Inc. Lukas Bachmann Quest - Discovery Stage Research Projects Expanded Capacity AAV Retinal Gene Therapy Enabled by Efficient RNA-Joining Technology $1,446,000
Immusoft Corporation Robert Hayes Clinical Trial Stage Projects A Phase I Open Label Study to Evaluate the Safety and Tolerability of ISP-001 in Patients with Mucopolysaccharidosis Type 1 $8,000,000
City of Hope, Beckman Research Institute Jianhua Yu Quest - Discovery Stage Research Projects Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $2,263,500
The American Society of Gene & Cell Therapy Eddie Hopkins Conference II The American Society of Gene & Cell Therapy: 26th Annual Meeting $50,000
University of California, Irvine Mathew Blurton-Jones Conference II ALSP Community Conference: Insights and Potential of Cell-Based Therapies for the Treatment of Leukodystrophies $42,500
University of California, San Francisco Karin Gaensler Late Stage Preclinical Projects Development of TriLeukeVax, an Engineered Autologous Leukemia Vaccine for Stimulating Cytolytic Immune Responses to Residual Leukemic Stem Cells $6,000,000
University of California, Davis Joseph Anderson Late Stage Preclinical Projects Hematopoetic stem cell gene therapy for the treatment of Tay-Sachs disease $4,048,253
Nammi Therapeutics, Inc. David Stover Late Stage Preclinical Projects IND-Enabling activities for the masked immunocytokine, QXL138AM $3,999,113
Angiocrine Bioscience, Inc. Paul Finnegan Clinical Trial Stage Projects AB-205-301 Phase 3 Trial and Related Activities to Support Clinical Development of AB-205 $15,000,000
Stanford University Alice Bertaina Clinical Trial Stage Projects Sequential same donor αβdepleted-HSCT from an HLA-partially matched donor allowing immunosuppression free kidney transplant $11,998,188
Tachyon Therapeutics, Inc Ivan King Clinical Trial Stage Projects TACH101: A Potent, First-In-Class KDM4 Inhibitor for Advanced Cancers $7,141,843
University of California, San Diego Stephanie Cherqui Therapeutic Translational Research Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
University of California, Davis William Murphy Therapeutic Translational Research Projects Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector $3,869,061
Mahzi Therapeutics Allyson Berent Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Pitt Hopkins Syndrome (PHS) - Translating from Animal Proof of Concept to Support Pre-IND Meeting $4,000,000
City of Hope, Beckman Research Institute Jianhua Yu Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
Greenstone Biosciences Nikesh Kotecha Tool Translational Research Projects Cell Villages and Clinical Trial in a Dish with Pooled iPSC-CMs for Drug Discovery $1,350,000
Stanford University Natalia Gomez-Ospina Late Stage Preclinical Projects Genome Editing of Autologous Hematopoietic Stem Cells to Treat Severe Mucopolysaccharidosis type 1 (Hurler Syndrome) $5,444,353
The Biomedical Engineering Society Charity Quick Conference II 2023 BMES-CMBE Annual Meeting: "Cell State Transitions in Health, Disease, and Regeneration” $22,000
Midwinter Conference of Immunologists Christel Uittenbogaart Conference II 61st Midwinter Conference of Immunologists $48,566
Cedars-Sinai Medical Center Wafa Tawackoli Conference II 13th Annual California ALS Research Summit $50,000
International Society for Stem Cell Research Chris Barry Conference II ISSCR Nucleus Forum 2023 $25,000
Calidi Biotherapeutics Boris Minev Late Stage Preclinical Projects Allogeneic mesenchymal stem cells loaded with oncolytic virus for cancer treatment $3,111,467
City of Hope, Beckman Research Institute Jana Portnow Clinical Trial Stage Projects A Phase I Study of Multiple doses of NSC-Based Oncolytic Virotherapy Administered Intracerebrally to Patients with Recurrent High-Grade Gliomas $11,999,984
Stanford University Matthew Porteus Alpha Stem Cell Clinics Network Expansion The Stanford Alpha Stem Cell Clinic $6,920,810
University of California, San Francisco Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) Alpha Stem Cell Clinic (ASCC) $7,994,347
Cedars-Sinai Medical Center Michael Lewis Alpha Stem Cell Clinics Network Expansion A comprehensive stem cell and gene therapy clinic to advance new therapies for a diverse patient population in California $7,957,966
City of Hope, Beckman Research Institute Leo Wang Alpha Stem Cell Clinics Network Expansion The City of Hope Alpha Clinic: A roadmap for equitable and inclusive access to regenerative medicine therapies for all Californians $8,000,000
University of California, Davis Mehrdad Abedi Alpha Stem Cell Clinics Network Expansion Alpha Stem Cell Clinic for Northern and Central California $7,999,997
University of California, San Diego Catriona Jamieson Alpha Stem Cell Clinics Network Expansion UC San Diego Health CIRM Alpha Stem Cell Clinic $8,000,000
University of California, Los Angeles Noah Federman Alpha Stem Cell Clinics Network Expansion Expansion of the Alpha Stem Cell and Gene Therapy Clinic at UCLA $8,000,000
University of Southern California Thomas Buchanan Alpha Stem Cell Clinics Network Expansion Alpha Clinic Network Expansion for Cell and Gene Therapies $7,999,983
University of California, Irvine Daniela Bota Alpha Stem Cell Clinics Network Expansion A hub and spoke community model to equitably deliver regenerative medicine therapies to diverse populations across four California counties $8,000,000
Summit for Stem Cell Foundation Melissa King Conference II Summit Live Continuing Medical Education (CME) Webinar Series: Educating Medical Professionals, Patient Advocates and the Public About Evidence-Based Regenerative Medicine and Stem Cells $50,000
Excision BioTherapeutics William Kennedy Clinical Trial Stage Projects Phase 1 Clinical research program for functional cure of HIV with EBT-101, in-vivo gene therapy $6,852,486
University of California, San Diego Francesca Soncin Foundation - Discovery Stage Research Projects Drivers of trophoblast stem/progenitor cell identity in human placenta $993,881
University of California, Los Angeles Melissa Spencer Foundation - Discovery Stage Research Projects Engineering AAV capsids for transduction of neural and muscle stem cells $999,999
University of California, San Francisco Harold Chapman Foundation - Discovery Stage Research Projects Modulation of human alveolar stem cells to promote lung regeneration and avoid pulmonary fibrosis $1,626,001
University of California, Berkeley Michael Rape Foundation - Discovery Stage Research Projects Control of OCT4 abundance and function in human stem cells $1,234,023
University of California, San Francisco Robert Blelloch Foundation - Discovery Stage Research Projects Development of universal off-the-shelf iPSC derived dendritic cells for use as patient specific anti-tumor vaccine $1,391,999
University of California, San Diego Alexis Komor Foundation - Discovery Stage Research Projects Development of a stem-cell based approach to interpret global effects of genetic variants contributing to neurodevelopmental disease risk $1,518,982
University of California, San Diego Heidi Cook-Andersen Foundation - Discovery Stage Research Projects Towards a trophectoderm stem-cell model representing human blastocysts of the highest implantation potential $1,584,000
Stanford University Marius Wernig Foundation - Discovery Stage Research Projects Developing a microglia replacement therapy $1,378,365
Greenstone Biosciences Syed Ahmed Foundation - Discovery Stage Research Projects Drug Discovery for Dilated Cardiomyopathy using Patient-Derived Human iPSCs $1,350,000
Gladstone Institutes, J. David Julia Kaye Foundation - Discovery Stage Research Projects Developing a Human Model of Sporadic ALS Using Machine Learning and Robotic Microscopy $1,406,622
University of California, Santa Barbara Dennis Clegg COMPASS Training Grant Training and mentorship program in stem cell biology and engineering: A COMPASS for the future $2,746,000
University of California, Los Angeles Tracy Johnson COMPASS Training Grant COMPASS: Accelerating Stem Cell Research by Educating and Empowering New Stem Cell Researchers $2,910,000
University of California, Berkeley John Matsui COMPASS Training Grant The COMPASS Scholars Program – Developing Today’s Untapped Talent into Tomorrow’s STEM Cell Researchers $2,908,950
University of Southern California Senta Georgia COMPASS Training Grant USC COMPASS: Guiding Undergraduates to Careers in Regenerative Medicine $2,899,999
Solano Community College James Dekloe COMPASS Training Grant IDEA-CBMS - Increase Diversity, Equity, and Advancement in Cell Based Manufacturing Sciences $2,894,500
MiraCosta College Michael Fino COMPASS Training Grant Increase Diversity, Equity, and Advancement in Cell Based Manufacturing Sciences (IDEA-CBMS) $2,894,500
University of California, Davis Alice Tarantal COMPASS Training Grant COMPASS Undergraduate Program $2,909,950
The Regents of the University of California on behalf of its Riverside Campus Huinan Liu COMPASS Training Grant Research Training and Mentorship Program to Inspire Diverse Undergraduates toward Regenerative Medicine Careers (RAMP) $2,910,000
University of California, Irvine Brian Cummings COMPASS Training Grant Research Mentorship Program in Regenerative Medicine Careers for a Diverse Undergraduate Student Body $2,729,900
Cal State Univ, Fullerton Alison Miyamoto COMPASS Training Grant COMPASS: an inclusive Pipeline for Research and Other Stem cell-based Professions in Regenerative medicine (iPROSPR) $2,880,800
Cal State Univ, San Bernadino Daniel Nickerson COMPASS Training Grant Student Pluripotency: Realizing Untapped Undergraduate Potential in Regenerative Medicine $2,909,853
The University Corporation at California State University, Northridge Cindy Malone COMPASS Training Grant CSUN CIRM COMPASS Training Program (N-COMPASS) $2,777,700
California State University San Marcos Corporation Bianca Mothe COMPASS Training Grant COMPASS Program for Southern California Hispanic Serving Institution $2,811,200
San Francisco State University Lily Chen COMPASS Training Grant Inclusive Pathways for a Stem Cell Scholar (iPSCS) Undergraduate Training Program $2,894,500
University of California, Merced Kara McCloskey COMPASS Training Grant Training Undergraduates in Stem Cell Engineering and Biology (TUSCEB) $2,909,999
Cal Poly Corporation, an Auxiliary of California Polytechnic State University, San Luis Obispo Kristen Cardinal COMPASS Training Grant A COMPASS to guide the growth of a diverse regenerative medicine workforce that represents California and benefits the world $2,887,939
University of California, San Francisco Rong Wang Conference II 22nd International Vascular Biology Meeting $50,000
RARE-X Nicole Boice Conference II RARE-X User's Summit - Patients' Data Powering Progress $50,000
Cedars-Sinai Medical Center Wafa Tawackoli Conference II Advances in Therapeutic Applications of Stem Cells $50,000
ImmunoVec Ryan Wong Late Stage Preclinical Projects Hematopoietic Stem Cell Gene Therapy for XCGD $3,999,959
Wake Forest University Health Sciences James Yoo Clinical Trial Stage Projects Phase I Treatment of Urethral Strictures in Humans $3,841,593
University of California, Davis Kyle Fink Quest - Discovery Stage Research Projects AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder $1,429,378
Scripps Research Institute Michael Bollong Quest - Discovery Stage Research Projects Therapeutics to overcome the differentiation roadblock in Myelodysplastic Syndrome (MDS) $1,244,160
Cedars-Sinai Medical Center Robert Barrett Quest - Discovery Stage Research Projects A new precision medicine based iPSC-derived model to study personalized intestinal fibrosis treatments in pediatric patients with Crohn’s disease $776,340
University of California, San Diego Michael Karin Quest - Discovery Stage Research Projects Targeting pancreatic cancer stem cells with DDR1 antibodies. $1,425,600
University of California, Los Angeles Dinesh Rao Quest - Discovery Stage Research Projects Novel methods to eliminate cancer stem cells $1,384,347
Scripps Research Institute Stuart Lipton Quest - Discovery Stage Research Projects Drug Development of Inhibitors of Inflammation Using Human iPSC-Derived Microglia (hiMG) $1,658,123
University of California, San Diego Joseph Gleeson Quest - Discovery Stage Research Projects Novel antisense therapy to treat genetic forms of neurodevelopmental disease. $1,180,654
University of California, Los Angeles Xian-Jie Yang Quest - Discovery Stage Research Projects Developing gene therapy for dominant optic atrophy using human pluripotent stem cell-derived retinal organoid disease models $1,345,691
Nanotools Bioscience Alex Savtchenko Quest - Discovery Stage Research Projects Enabling non-genetic activity-driven maturation of iPSC-derived neurons $675,000
Minutia, Inc. Katy Digovich Quest - Discovery Stage Research Projects Bioengineering human stem cell-derived beta cell organoids to monitor cell health in real time and improve therapeutic outcomes in patients $1,198,550
University of California, Los Angeles Lili Yang Quest - Discovery Stage Research Projects Combating Ovarian Cancer Using Stem Cell-Engineered Off-The-Shelf CAR-iNKT Cells $1,404,000
University of California, Irvine Michael Demetriou Quest - Discovery Stage Research Projects CAR T cells targeting abnormal N-glycans for the treatment of refractory/metastatic solid cancers $1,414,800
Tenaya Therapeutics, Inc. Timothy Hoey Quest - Discovery Stage Research Projects Cardiac Reprogramming Gene Therapy for Post-Myocardial Infarction Heart Failure $1,017,000
The Scintillon Institute Brian Lawson Quest - Discovery Stage Research Projects An hematopoietic stem-cell-based approach to treat HIV employing CAR T cells and anti-HIV broadly neutralizing antibodies. $1,143,600
Stanford University Judith Shizuru Quest - Discovery Stage Research Projects Targeted Immunotherapy-Based Blood Stem Cell Transplantation $1,341,910
Gladstone Institutes, J. David Deepak Srivastava Quest - Discovery Stage Research Projects Modified RNA-Based Gene Therapy for Cardiac Regeneration Through Cardiomyocyte Proliferation $1,565,784
University of California, Los Angeles Donald Kohn Quest - Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for Alpha Thalassemia $1,177,739
University of California, San Diego Alysson Muotri Quest - Discovery Stage Research Projects A treatment for Rett syndrome using glial-restricted neural progenitor cells $1,402,240
University of California, Los Angeles Caroline Kuo Quest - Discovery Stage Research Projects Defining the Optimal Gene Therapy Approach of Human Hematopoietic Stem Cells for the Treatment of Dedicator of Cytokinesis 8 (DOCK8) Deficiency $1,386,232

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