All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Cedars-Sinai Medical Center Dhruv Sareen Manufacturing Network Grant A comprehensive biomanufacturing center solving bottlenecks in cell and gene therapy manufacturing to accelerate new therapies for California patients $2,000,000
Stanford University Steven Feldman Manufacturing Network Grant Laboratory for Cell and Gene Medicine: A partner in the California Cell and Gene Therapy Manufacturing Network $2,000,000
University of California, San Francisco Brian Shy Manufacturing Network Grant Open Manufacturing Network for Cell and Gene Therapies $1,999,993
University of California, Los Angeles Dawn Ward Manufacturing Network Grant Enhancing California’s Manufacturing of Leading-Edge Cell & Gene Therapies $2,000,000
City of Hope, Beckman Research Institute Taby Ahsan Manufacturing Network Grant Scalable Expansion for Stem Cell-derived Therapies $1,998,174
Eureka Therapeutics, Inc. Pei Wang Clinical Trial Stage Projects Autologous ARTEMIS® T Cells to Treat Refractory/Relapsed Pediatric Liver Cancer $10,600,072
University of California, Los Angeles Steven Schwartz Late Stage Preclinical Projects Clinical Translation of Autologous Regenerative Pluripotent Stem Cell Therapy for Blindness $6,000,000
University of California, Irvine Kyriacos Athanasiou Late Stage Preclinical Projects Treatment of the TMJ disc complex $6,000,000
Stanford University Matthew Porteus Clinical Trial Stage Projects Reduced intensity conditioning with JSP191 prior to TCRαβ+ T-cell/CD19+ B-cell depleted hematopoietic stem cell transplant for Fanconi Anemia patients $10,642,420
Combangio, Inc. R. Brazzell Clinical Trial Stage Projects Phase 2b Clinical Study of KPI-012 Topical Ophthalmic Human Mesenchymal Stem Cell Secretome for the Treatment of Persistent Corneal Epithelial Defect $15,000,000
VxBiosciences inc. Leor Weinberger Therapeutic Translational Research Projects Escape-Resistant Oligonucleotide Therapy (ONT) for Cytomegalovirus (CMV) Disease in Hematopoietic Stem-Cell and Solid-Organ Transplant Patients $3,977,180
Stanford University Walter Park Therapeutic Translational Research Projects Enhanced Autologous Pancreatic Islet Transplantation and Survival for Diabetes Mellitus Therapy $6,056,713
University of Southern California Rongfu Wang Therapeutic Translational Research Projects Novel T cell receptor-STEM T cell immunotherapy in lung cancer $5,689,540
Rejuvenation Technologies, Inc. John Ramunas Therapeutic Translational Research Projects Telomerase mRNA for short telomere related pulmonary fibrosis $3,984,942
University of California, Los Angeles Scott Kitchen Therapeutic Translational Research Projects Hematopoietic Stem/Progenitor Cell-Based Chimeric Antigen Receptor Gene Therapy for HIV Infection $6,140,723
University of California, Los Angeles Sophie Deng Therapeutic Translational Research Projects Extracellular Vesicle-Based Therapy for Corneal Scars $5,779,276
BrainXell Therapeutics Emmanuel Baetge Therapeutic Translational Research Projects Development of Autologous Cell Replacement Therapy for Parkinson’s Disease: Path to Personalized Treatment $3,841,110
ImmunoVec Luke Riggan Therapeutic Translational Research Projects Hematopoietic Stem Cell Gene Therapy for Wiskott Aldrich Syndrome $3,999,899
University of California, Los Angeles Anthony Aldave Therapeutic Translational Research Projects AAV Gene Therapy for Treating Congenital Hereditary Endothelial Dystrophy associated with Biallelic SLC4A11 Mutations $4,338,166
City of Hope, Beckman Research Institute Michael Caligiuri Therapeutic Translational Research Projects Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
Cedars-Sinai Medical Center Wafa Tawackoli Conference II 1st Annual Greater Los Angeles Regenerative Medicine Summit $35,100
Lineage Cell Therapeutics, Inc. Ioana Hone Conference II 1st Annual Spinal Cord Injury Investor Symposium (SCIIS) $50,000
University of California, San Francisco Jeffrey Lotz Conference II 2023 Center for Dental, Oral, & Craniofacial Tissue & Organ Regeneration (C-DOCTOR) Annual Spring Conference $30,250
University of Southern California Qifa Zhou Conference II The 15th International Conference on the Ultrasound Engineering and Biomedical Applications $25,000
University of California, San Francisco Elizabeth Crouch Foundation - Discovery Stage Research Projects Harnessing vascular stem cells to grow and protect the human brain $1,391,998
University of California, Los Angeles Gay Crooks Foundation - Discovery Stage Research Projects Engineering pluripotent stem cells for universally available, off-the-shelf T cell therapies $1,352,753
University of California, San Diego Alon Goren Foundation - Discovery Stage Research Projects Establishment of a novel approach to systematically study the dynamic organization of protein complexes in stem cells $1,515,601
Scripps Research Institute Xin Jin Foundation - Discovery Stage Research Projects Functional genomics to study cellular convergence across ASD risk genes in neurodevelopment $1,575,001
University of California, San Francisco Tomasz Nowakowski Foundation - Discovery Stage Research Projects Identifying roadblocks to neural stem cell transplantation into human tissues. $1,551,394
University of California, Irvine Brian Cummings Foundation - Discovery Stage Research Projects Mapping the spatial and temporal responses of hESC-derived microglia to repeat mild closed head injury to identify therapeutic targets and mechanisms $1,555,140
University of California, Irvine Albert La Spada Foundation - Discovery Stage Research Projects Role of ataxin-3 polyadenylation site selection in ALS neuron toxicity and disease pathogenesis $1,514,416
University of California, San Francisco Deepak Lamba Foundation - Discovery Stage Research Projects Modeling Retinitis Pigmentosa using patient-derived human iPSC organoids $1,612,617
University of California, Los Angeles Brigitte Gomperts Foundation - Discovery Stage Research Projects Overcoming barriers for airway stem cell gene therapy for Cystic Fibrosis $1,472,858
University of California, San Francisco TIEN PENG Foundation - Discovery Stage Research Projects Ex vivo fate mapping of human lung stem cell plasticity in fibrotic disease $1,625,998
University of California, Los Angeles Kathrin Plath Foundation - Discovery Stage Research Projects Characterization and applications of human blastoids for understanding early human embryogenesis $1,402,137
University of California, Santa Cruz Maximilian Haeussler Foundation - Discovery Stage Research Projects An interactive data resource for hypothesis testing in stem cell single-cell gene expression and validation of the results with brain organoids $1,160,126
University of California, Los Angeles William Lowry Foundation - Discovery Stage Research Projects Defining the source of dysfunction in monogenic Intellectual Disability Syndrome neurons $1,500,337
University of California, San Francisco Faranak Fattahi Foundation - Discovery Stage Research Projects hPSC-derived enteric ganglioids for cell therapy in gastrointestinal motility disorders $1,589,307
Cedars-Sinai Medical Center Dmitriy Sheyn Foundation - Discovery Stage Research Projects The role of WNT and BMP signaling pathways in iPSC to iTenocyte step-wise differentiation for tendon repair $1,516,563
University of California, San Francisco Yin Shen Foundation - Discovery Stage Research Projects Understanding Chemotherapy-Induced Peripheral Neuropathy Mechanisms using CRISPRi and Chemical Screens in Human iPSC-Derived Sensory Neurons $1,621,913
University of California, Santa Cruz Camilla Forsberg Foundation - Discovery Stage Research Projects Determining how age-specific heterogeneity of human hematopoietic stem cells and megakaryocyte progenitors contribute to thrombotic disease upon aging $1,536,000
Cedars-Sinai Medical Center Wafa Tawackoli Conference - Manage The SPARK Annual Meeting 2023 CIRM SPARK Research Conference $100,000
Rampart Bioscience Jeffrey Bartlett Late Stage Preclinical Projects Ex vivo Engineering of Autologous Hematopoietic Stem Cells for the Treatment of Hypophosphatasia $3,999,980
Genascence Corporation Thomas Chalberg Clinical Trial Stage Projects A Phase 1b, Randomized, Blinded, Placebo-Controlled Dose-Ranging Study of GNSC-001 Evaluating Safety, Pharmacodynamics, and Biomarkers in Knee OA $11,637,194
Stanford University Joseph Wu Conference II Stanford Drug Discovery Symposium 2023 $50,000
University of California, Berkeley John Dueber Conference II BIC 2023 - 23rd Annual UC Systemwide Bioengineering Symposium $50,000
Stanford University Everett Meyer Conference II Cellular Immune Tolerance Symposium $32,751
University of California, Davis Aijun Wang Quest - Discovery Stage Research Projects In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing $2,035,544
University of California, Berkeley Fyodor Urnov Quest - Discovery Stage Research Projects A Treatment for Artemis-deficient Severe Combined Immunodeficiency using Non-Viral CRISPR-driven Safe Harbor Transgenesis in Hematopoietic Stem Cells $1,809,372
Greenstone Biosciences, Inc. Paul Pang Quest - Discovery Stage Research Projects Drug Discovery for Duchenne Muscular Dystrophy Using Patient-Derived Human iPSCs $675,000
University of California, Los Angeles Richard Pietras Quest - Discovery Stage Research Projects Reversal of dysregulated myelopoiesis in breast cancers and cancer stem cells to boost antitumor immunotherapy $2,327,680
University of California, Los Angeles Song Li Quest - Discovery Stage Research Projects Vax-CT to promote formation of cancer-specific T memory stem cell for personalized cancer immunotherapy $2,267,714
Ossium Health Brian Johnstone Late Stage Preclinical Projects Development of OSSM-007, cryopreserved interferon-gamma primed allogeneic MSCs, for treatment of steroid refractory acute graft versus host disease $3,457,858
Gladstone Institutes, J. David Lyandysha Zholudeva Quest - Discovery Stage Research Projects Excitatory spinal interneurons from human pluripotent stem cells to treat spinal cord injury $2,942,198
Ryne Bio Howard Federoff Late Stage Preclinical Projects Allogeneic iPSC derived Dopaminergic Drug Product for Parkinson's disease $4,000,000
City of Hope, Beckman Research Institute Jianhua Yu Quest - Discovery Stage Research Projects Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $2,263,500
Immusoft Corporation Robert Hayes Clinical Trial Stage Projects A Phase I Open Label Study to Evaluate the Safety and Tolerability of ISP-001 in Patients with Mucopolysaccharidosis Type 1 $8,000,000
BrainXell Therapeutics Matthew Goodus Quest - Discovery Stage Research Projects Autologous stem cell-derived interneuron cell therapy for spinal cord injury (SCI) $2,025,000
University of California, Berkeley Kevin Healy Quest - Discovery Stage Research Projects Novel Lipid Nanoparticles for Enhancing eNOS Synthesis for Cardioprotection Post Myocardial Infarction $2,060,248
Lundquist Institute for Biomedical Innovation at Harbor - UCLA Medical Center Michelina Iacovino Quest - Discovery Stage Research Projects A Novel Therapy for Sanfilippo B $2,297,884
Cedars-Sinai Medical Center Dmitriy Sheyn Quest - Discovery Stage Research Projects Microgel encapsulated iPSC-derived notochordal cells to treat intervertebral disc degeneration and low back pain $2,020,166
Scripps Health Darryl D’Lima Quest - Discovery Stage Research Projects Pluripotent Stem Cells for Tendon Tissue Engineering $2,734,163
University of California, Los Angeles Frank Pajonk Quest - Discovery Stage Research Projects Development of novel small molecules against cancer stem cells in solid cancers $2,340,000
University of California, Los Angeles Gerald Lipshutz Quest - Discovery Stage Research Projects Gene Therapy for SLC6A8 Creatine Transporter Disorder $2,296,920
Rubedo Life Sciences Inc. Marco Quarta Quest - Discovery Stage Research Projects Pharmacological regenerative treatment of idiopathic pulmonary fibrosis targeting the senescent niche of lung progenitor cells. $1,450,876
The American Society of Gene & Cell Therapy Eddie Hopkins Conference II The American Society of Gene & Cell Therapy: 26th Annual Meeting $50,000
University of California, Irvine Mathew Blurton-Jones Conference II ALSP Community Conference: Insights and Potential of Cell-Based Therapies for the Treatment of Leukodystrophies $42,500
University of California, Davis Joseph Anderson Late Stage Preclinical Projects Hematopoetic stem cell gene therapy for the treatment of Tay-Sachs disease $4,048,253
Nammi Therapeutics, Inc. David Stover Late Stage Preclinical Projects IND-Enabling activities for the masked immunocytokine, QXL138AM $3,999,113
Angiocrine Bioscience, Inc. Paul Finnegan Clinical Trial Stage Projects AB-205-301 Phase 3 Trial and Related Activities to Support Clinical Development of AB-205 $15,000,000
University of California, San Francisco Karin Gaensler Late Stage Preclinical Projects Development of TriLeukeVax, an Engineered Autologous Leukemia Vaccine for Stimulating Cytolytic Immune Responses to Residual Leukemic Stem Cells $6,000,000
Stanford University Natalia Gomez-Ospina Late Stage Preclinical Projects Genome Editing of Autologous Hematopoietic Stem Cells to Treat Severe Mucopolysaccharidosis type 1 (Hurler Syndrome) $5,444,353
Stanford University Alice Bertaina Clinical Trial Stage Projects Sequential same donor αβdepleted-HSCT from an HLA-partially matched donor allowing immunosuppression free kidney transplant $11,998,188
Tachyon Therapeutics, Inc Ivan King Clinical Trial Stage Projects TACH101: A Potent, First-In-Class KDM4 Inhibitor for Advanced Cancers $7,141,843
University of California, San Diego Stephanie Cherqui Therapeutic Translational Research Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $4,846,579
University of California, Davis William Murphy Therapeutic Translational Research Projects Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector $3,869,061
Mahzi Therapeutics Allyson Berent Therapeutic Translational Research Projects Development of a Gene Therapy for the Treatment of Pitt Hopkins Syndrome (PHS) - Translating from Animal Proof of Concept to Support Pre-IND Meeting $3,800,760
City of Hope, Beckman Research Institute Jianhua Yu Therapeutic Translational Research Projects Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
Greenstone Biosciences, Inc. Paul Pang Tool Translational Research Projects Cell Villages and Clinical Trial in a Dish with Pooled iPSC-CMs for Drug Discovery $1,350,000
The Biomedical Engineering Society Charity Quick Conference II 2023 BMES-CMBE Annual Meeting: "Cell State Transitions in Health, Disease, and Regeneration” $22,000
Midwinter Conference of Immunologists Christel Uittenbogaart Conference II 61st Midwinter Conference of Immunologists $48,566
Cedars-Sinai Medical Center Wafa Tawackoli Conference II 13th Annual California ALS Research Summit $50,000
International Society for Stem Cell Research Chris Barry Conference II ISSCR Nucleus Forum 2023 $25,000
University of California, Los Angeles Noah Federman Alpha Stem Cell Clinics Network Expansion Expansion of the Alpha Stem Cell and Gene Therapy Clinic at UCLA $8,000,000
University of Southern California Thomas Buchanan Alpha Stem Cell Clinics Network Expansion Alpha Clinic Network Expansion for Cell and Gene Therapies $7,999,983
University of California, Irvine Daniela Bota Alpha Stem Cell Clinics Network Expansion A hub and spoke community model to equitably deliver regenerative medicine therapies to diverse populations across four California counties $8,000,000
Calidi Biotherapeutics, Inc. Boris Minev Late Stage Preclinical Projects Allogeneic mesenchymal stem cells loaded with oncolytic virus for cancer treatment $3,111,467
City of Hope, Beckman Research Institute Jana Portnow Clinical Trial Stage Projects A Phase I Study of Multiple doses of NSC-Based Oncolytic Virotherapy Administered Intracerebrally to Patients with Recurrent High-Grade Gliomas $11,999,984
Stanford University Matthew Porteus Alpha Stem Cell Clinics Network Expansion The Stanford Alpha Stem Cell Clinic $6,920,810
University of California, San Francisco Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) Alpha Stem Cell Clinic (ASCC) $7,994,347
Cedars-Sinai Medical Center Michael Lewis Alpha Stem Cell Clinics Network Expansion A comprehensive stem cell and gene therapy clinic to advance new therapies for a diverse patient population in California $7,957,966
City of Hope, Beckman Research Institute Leo Wang Alpha Stem Cell Clinics Network Expansion The City of Hope Alpha Clinic: A roadmap for equitable and inclusive access to regenerative medicine therapies for all Californians $8,000,000
University of California, Davis Mehrdad Abedi Alpha Stem Cell Clinics Network Expansion Alpha Stem Cell Clinic for Northern and Central California $7,999,997
University of California, San Diego Catriona Jamieson Alpha Stem Cell Clinics Network Expansion UC San Diego Health CIRM Alpha Stem Cell Clinic $8,000,000
Summit for Stem Cell Foundation Melissa King Conference II Summit Live Continuing Medical Education (CME) Webinar Series: Educating Medical Professionals, Patient Advocates and the Public About Evidence-Based Regenerative Medicine and Stem Cells $50,000
University of California, Berkeley Michael Rape Foundation - Discovery Stage Research Projects Control of OCT4 abundance and function in human stem cells $1,234,023
University of California, San Francisco Robert Blelloch Foundation - Discovery Stage Research Projects Development of universal off-the-shelf iPSC derived dendritic cells for use as patient specific anti-tumor vaccine $1,391,999
University of California, San Diego Alexis Komor Foundation - Discovery Stage Research Projects Development of a stem-cell based approach to interpret global effects of genetic variants contributing to neurodevelopmental disease risk $1,518,982
University of California, San Diego Heidi Cook-Andersen Foundation - Discovery Stage Research Projects Towards a trophectoderm stem-cell model representing human blastocysts of the highest implantation potential $1,584,000
Stanford University Marius Wernig Foundation - Discovery Stage Research Projects Developing a microglia replacement therapy $1,378,365

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