Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
| Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
|---|---|---|---|---|---|---|
| Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Navega Therapeutics |  |
Development Candidate, Proof of Concept | |
| Heart Disease | iPS Cell | Model system development, Specific Cell Type Derivation, Technology | Stanford | |
Development Candidate, Proof of Concept | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | Adult or Tissue Stem Cell | Donor cell therapy, Small molecule therapy, Therapeutic Approach | UCSD | |
Development Candidate, Proof of Concept | |
| Epidermolysis Bullosa, Skin Disease | iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Heart Disease, Heart failure | Embryonic Stem Cell, iPS Cell | Biologic, Exosomes based therapy, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Heart Disease | iPS Cell | Donor cell therapy, Therapeutic Approach | UC Davis | |
Development Candidate, Proof of Concept | |
| Liver Disease, Metabolic Disorders | iPS Cell | Donor cell therapy, Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | CHLA | |
Development Candidate, Proof of Concept | |
| Cancer, Solid Tumors | Adult or Tissue Stem Cell | Technology | Stanford | Tool/Resources/Bottleneck | ||
| iPS Cell | Cell processing & handling, Technology | Defined Bioscience, Inc. | Tool/Resources/Bottleneck | |||
| iPS Cell | Cell Line Generation-Resource, Gene Therapy (All), Gene-modified, donor cell therapy, Immune tolerance/management, Technology, Therapeutic Approach | HEALIOS NA, Inc. | Tool/Resources/Bottleneck | |||
| aa Multiple Diseases (Centers & Resoures) | Cell processing & handling, Technology | UC Davis |  |
Tool/Resources/Bottleneck | ||
| Other, Toxicity | iPS Cell | Model system development, Technology | Greenstone Biosciences | |
Tool/Resources/Bottleneck | |
| Heart Disease | iPS Cell | Model system development, Technology | Organos, Inc. | |
Tool/Resources/Bottleneck | |
| Kidney Disease, Kidney Failure | Adult or Tissue Stem Cell | Device, Technology, Therapeutic Approach, Tissue engineering | UC Davis | |
Pre-IND/IDE or Equivalent | |
| Breast Cancer, Cancer, Solid Tumors | Cancer Stem Cell | Assay development, Diagnostic Test, Technology | Cedars-Sinai | |
Regulated Lab Test, Ready for Validation | |
| Epilepsy, Neurological Disorders | Embryonic Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Neurona Therapeutics | |
Pre-IND/IDE or Equivalent | |
| Cancer, Ovarian Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, Bone or Cartilage Disease, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Pre-IND/IDE or Equivalent | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | AcuraStem Incorporated | |
Pre-IND/IDE or Equivalent | ||
| Neurological Disorders, Parkinson's Disease | Embryonic Stem Cell | Cell processing & handling, Donor cell therapy, Technology, Therapeutic Approach | Axent Biosciences Inc. | |
Pre-IND/IDE or Equivalent | |
| Metabolic Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Age-related macular degeneration, Vision Loss | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Ray Therapeutics, INC | |
Pre-IND/IDE or Equivalent | |
| Other | Adult or Tissue Stem Cell | Small molecule therapy, Therapeutic Approach | UCSF | |
Pre-IND/IDE or Equivalent | |
| Brain Cancer, Cancer, Solid Tumors | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Siren Biotechnology, Inc. | |
Pre-IND/IDE or Equivalent | |
| Bone or Cartilage Disease, Immune Disease, Skin Disease, Tendon/Ligament/Connective Tissue Injury or Disorder | Biologic, Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Cedars-Sinai | |
Pre-IND/IDE or Equivalent | ||
| Heart Disease | Adult or Tissue Stem Cell | Biologic, Therapeutic Approach | UCSD | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders, Genetic Disorder | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Danon Disease, Genetic Disorder, Metabolic Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSD | |
Pre-IND/IDE or Equivalent | |
| Metabolic Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | |
Pre-IND/IDE or Equivalent | |
| Corneal Damage, Vision Loss | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Parkinson's Disease | iPS Cell | Personalized cell therapy, Therapeutic Approach | BrainXell Therapeutics | |
Pre-IND/IDE or Equivalent | |
| Corneal Damage, Vision Loss | Adult or Tissue Stem Cell | Biologic, Exosomes based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| HIV/AIDS, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Lung Disease, Fibrosis, Respiratory Disorders | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | Rejuvenation Technologies, Inc. | |
Pre-IND/IDE or Equivalent | ||
| Cancer, Lung Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | USC | |
Pre-IND/IDE or Equivalent | |
| Diabetes, Metabolic Disorders | Personalized cell therapy, Therapeutic Approach | Stanford | |
Pre-IND/IDE or Equivalent | ||
| Infectious Disease | Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach | VxBiosciences inc. | |
Pre-IND/IDE or Equivalent | ||
| Breast Cancer, Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Pediatrics | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Mahzi Therapeutics | |
Pre-IND/IDE or Equivalent | ||
| B cell cancers, Blood Cancer, Cancer | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Davis | |
Pre-IND/IDE or Equivalent | ||
| Genetic Disorder, Neurological Disorders, Other, Pediatrics | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSD | |
Pre-IND/IDE or Equivalent | |
| Cancer, Prostate Cancer, Solid Tumors | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | USC | |
Pre-IND/IDE or Equivalent | ||
| Heart Disease, Hypertension, pulmonary arterial, Pulmonary Hypertension | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Neurological Disorders, Spinal Cord Injury | Adult or Tissue Stem Cell | Donor cell therapy, Therapeutic Approach | UC Irvine | |
Pre-IND/IDE or Equivalent | |
| B cell cancers, Blood Cancer, Cancer | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
Pre-IND/IDE or Equivalent | |
| Duchenne Muscular Dystrophy, Skeletal/Smooth Muscle disorders | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | MyoGene Bio LLC | |
Pre-IND/IDE or Equivalent | |
| Genetic Disorder, Metabolic Disorders | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Immusoft Corporation | |
Pre-IND/IDE or Equivalent |
