Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Stereochemical basis for engineered pyrrolysyl-tRNA synthetase and the efficient in vivo incorporation of structurally divergent non-native amino acids. 2011 ACS Chem Biol
Suberoylanilide Hydroxamic Acid (Vorinostat) Up-regulates Progranulin Transcription: RATIONAL THERAPEUTIC APPROACH TO FRONTOTEMPORAL DEMENTIA. 2011 J Biol Chem
Successful Investigational New Drug Preparation without Reinventing the Wheel. 2011 J Invest Dermatol
Suppression of leukemia development caused by PTEN loss. 2011 Proc Natl Acad Sci U S A
Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs. 2011 Cell Stem Cell
Targeting SOX17 in human embryonic stem cells creates unique strategies for isolating and analyzing developing endoderm. 2011 Cell Stem Cell
Tbr1 and Fezf2 regulate alternate corticofugal neuronal identities during neocortical development. 2011 J Neurosci
Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function. 2011 J Clin Invest
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. 2011 Nature
Teratoma Generation in the Testis Capsule. 2011 J Vis Exp
The ageing systemic milieu negatively regulates neurogenesis and cognitive function. 2011 Nature
The challenges and promises of blood engineered from human pluripotent stem cells. 2011 Adv Drug Deliv Rev
The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-beta. 2011 Biomaterials
The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche. 2011 PLoS One
The gamma catenin/CBP complex maintains survivin transcription in beta-catenin deficient/depleted cancer cells. 2011 Curr Cancer Drug Targets
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. 2011 Nat Cell Biol
The Id3/E47 axis mediates cell cycle control in human pancreatic ducts and adenocarcinoma. 2011 Mol Cancer Res
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. 2011 Proc Natl Acad Sci U S A
The maternal immune response inhibits the success of in utero hematopoietic cell transplantation. 2011 Chimerism
The microbial opsin family of optogenetic tools. 2011 Cell
The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. 2011 Aging (Albany NY)
The Milieu of Damaged AEC2 Stimulates Alveolar Wound Repair by Endogenous and Exogenous Progenitors. 2011 Am J Respir Cell Mol Biol
The post-apoptotic fate of RNAs identified through high-throughput sequencing of human hair. 2011 PLoS One
The risk of putting something where it does not belong: mesenchymal stem cells produce masses in the brain. 2011 Exp Neurol
The role of anti-mullerian hormone (AMH) in assessing ovarian reserve. 2011 J Clin Endocrinol Metab
The therapeutic potential of phiC31 integrase as a gene therapy system. 2011 Expert Opin Biol Ther
Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma. 2011 Magn Reson Med
Therapeutic applications of the PhiC31 integrase system. 2011 Curr Gene Ther
Tissue-engineered small intestine. 2011 Expert Rev Med Devices
Tracking single hematopoietic stem cells in vivo using high-throughput sequencing in conjunction with viral genetic barcoding. 2011 Nat Biotechnol
Tracking stem cell differentiation in the setting of automated optogenetic stimulation. 2011 Stem Cells
Transcriptome Analysis of Neural Progenitor Cells by a Genetic Dual Reporter Strategy. 2011 Stem Cells
Transcriptomic Signature of Trophoblast Differentiation in a Human Embryonic Stem Cell Model. 2011 Biol Reprod
Transduction of Human Cells with Polymer-complexed Ecotropic Lentivirus for Enhanced Biosafety. 2011 J Vis Exp
Transferable cell-secreted extracellular matrices enhance osteogenic differentiation. 2011 Acta Biomater
Trophoblast stem cells. 2011 Biol Reprod
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. 2011 EMBO J
Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces. 2011 PLoS One
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. 2011 Nat Med
Vacuum soft lithography to direct neuronal polarization 2011 Soft Matter
VEGF optimizes the formation of tissue-engineered small intestine. 2011 Regen Med
Vitamin C treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity. 2011 J Cell Physiol
A 3-dimensional extracellular matrix as a delivery system for the transplantation of glioma-targeting neural stem/progenitor cells. 2010 Neuro Oncol
A call to standardize teratoma assays used to define human pluripotent cell lines. 2010 Cell Stem Cell
A matrix micropatterning platform for cell localization and stem cell fate determination. 2010 Acta Biomater
A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells. 2010 Cell
A model of motor neuron loss: selective deficits after ricin injection. 2010 J Neurotrauma
A modest proposal in response to Rhodes and Schiano. 2010 Am J Bioeth
A rapid pathway toward a superb gene delivery system: programming structural and functional diversity into a supramolecular nanoparticle library. 2010 ACS Nano
A study on the interactions between heparan sulfate proteoglycans and Wnt proteins. 2010 Dev Dyn