Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Multifocus microscopy with precise color multi-phase diffractive optics applied in functional neuronal imaging. 2016 Biomed Opt Express
Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation. 2016 J Control Release
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells. 2016 Nature
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. 2016 Cancer Cell
Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. 2016 Cell Stem Cell
NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. 2016 Cell Metab
Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery. 2016 Proc Natl Acad Sci U S A
Neurorestoration after stroke. 2016 Neurosurg Focus
Non-invasive Chamber-Specific Identification of Cardiomyocytes in Differentiating Pluripotent Stem Cells. 2016 Stem Cell Reports
Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate. 2016 Stem Cell Reports
Nuclear transfer nTreg model reveals fate-determining TCR-beta and novel peripheral nTreg precursors. 2016 Proc Natl Acad Sci U S A
p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway. 2016 Cell Rep
P53 Regulates Rapid Apoptosis in Human Pluripotent Stem Cells. 2016 J Mol Biol
Pancreatic Tissue Transplanted in TheraCyte Encapsulation Devices Is Protected and Prevents Hyperglycemia in a Mouse Model of Immune-Mediated Diabetes. 2016 Cell Transplant
Paramagnetic fluorinated nanoemulsions for sensitive cellular fluorine-19 magnetic resonance imaging. 2016 Nat Mater
Pathway-Based Genomics Prediction using Generalized Elastic Net. 2016 PLoS Comput Biol
Patterns of expression of factor VIII and von Willebrand factor by endothelial cell subsets in vivo. 2016 Blood
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. 2016 Cell
Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects. 2016 Prenat Diagn
Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration. 2016 J Ocul Pharmacol Ther
Potent spinal parenchymal AAV9-mediated gene delivery by subpial injection in adult rats and pigs. 2016 Mol Ther Methods Clin Dev
Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review. 2016 JAMA Cardiol
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice. 2016 PLoS One
Precise Correction of Disease Mutations in Induced Pluripotent Stem Cells Derived From Patients With Limb Girdle Muscular Dystrophy. 2016 Mol Ther
Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. 2016 Mol Ther Methods Clin Dev
Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia. 2016 Mol Ther Methods Clin Dev
Preeclampsia and Inflammatory Preterm Labor Alter the Human Placental Hematopoietic Niche. 2016 Reprod Sci
Primary Cilium-Autophagy-Nrf2 (PAN) Axis Activation Commits Human Embryonic Stem Cells to a Neuroectoderm Fate. 2016 Cell
Programmable RNA Tracking in Live Cells with CRISPR/Cas9. 2016 Cell
Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy. 2016 Stem Cells Dev
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. 2016 Neuron
Rare SOX2+ Airway Progenitor Cells Generate KRT5+ Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection. 2016 Stem Cell Reports
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases. 2016 Mol Ther Nucleic Acids
Regenerating Perfection. 2016 J Ocul Pharmacol Ther
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy. 2016 N Engl J Med
Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation. 2016 Adv Healthc Mater
Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. 2016 Cell
Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. 2016 PLoS One
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. 2016 Mol Ther Nucleic Acids
Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells. 2016 Cell Rep
Rewinding the process of mammalian extinction. 2016 Zoo Biol
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. 2016 Nat Struct Mol Biol
ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium. 2016 Transl Vis Sci Technol
ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation. 2016 Stem Cell Res
RUNX1 prevents oestrogen-mediated AXIN1 suppression and beta-catenin activation in ER-positive breast cancer. 2016 Nat Commun
Same-Single-Cell Analysis of Pacemaker-Specific Markers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Subtypes Classified by Electrophysiology. 2016 Stem Cells
Selecting for neurogenic potential as an alternative for Alzheimer’s disease drug discovery. 2016 Alzheimers Dement
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells. 2016 Sci Transl Med
Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease. 2016 PLoS One