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  • About
    • Our Mission
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Spinal ischemic paraplegia: modulation by human embryonic stem cell implant.

  • Post author:
  • Post published:May 9, 2025
  • Post category:

schemia-induced paraplegia often combined with a qualitatively defined increase in muscle tone (i.e. spasticity and rigidity) is a serious complication associated with a temporary aortic cross-clamping ( a surgical procedure…

Continue ReadingSpinal ischemic paraplegia: modulation by human embryonic stem cell implant.

microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells

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  • Post published:May 9, 2025
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Regenerative therapies could be particularly beneficial for heart disease, which is the leading killer of adults in the U.S, and is responsible for the 5 million Americans with insufficient cardiac…

Continue ReadingmicroRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells

Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

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  • Post published:May 9, 2025
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Human embryonic stem cells (hESCs) are pluripotent entities, capable of generating a whole-body spectrum of distinct cell types. We have developmental procedures for inducing hESCs to develop into pure populations…

Continue ReadingMolecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons

Human oocyte development for genetic, pharmacological and reprogramming applications

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  • Post published:May 9, 2025
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Continue ReadingHuman oocyte development for genetic, pharmacological and reprogramming applications

Constructing a fate map of the human embryo

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  • Post published:May 9, 2025
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The United States government does not fund research involving human embryos or cells that were grown from them after August 9, 2001. In addition, other restrictions have been imposed that…

Continue ReadingConstructing a fate map of the human embryo

The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning

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  • Post published:May 9, 2025
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n therapeutic cloning, a patient’s cell is combined (fused) to an enucleated donated egg (oocyte) from an unrelated woman or from another animal. It is hoped that cellular factors in…

Continue ReadingThe Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning

Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells

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  • Post published:May 9, 2025
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Parkinson’s disease (PD) is caused by degeneration of a specific population of dopamine-producing nerve cells in the brain and is chronic, progressive, and incurable. Loss of dopamine-containing cells results in…

Continue ReadingDerivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells

Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells

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  • Post published:May 9, 2025
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Cardiovascular disease (CVD) affects more than 71 million Americans and 1.7 million Californians. Recently, engineered cardiovascular tissue grafts, or “patches”, including one made from mouse embryonic stem cells (ESC), have…

Continue ReadingEngineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells

Immunology of neural stem cell fate and function

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  • Post published:May 9, 2025
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One of the most difficult yet ultimately rewarding goals in stem cell research is to repair damaged neural systems with newly generated neurons. Our work examining neuronal integration and survival…

Continue ReadingImmunology of neural stem cell fate and function

Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes

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  • Post published:May 9, 2025
  • Post category:

Adult heart muscle cells retain negligible proliferative capacity and this underlies the inability of the heart to replace muscle cells that are lost to injury, such as infarct, and underlies…

Continue ReadingChemical Genetic Approach to Production of hESC-derived Cardiomyocytes
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