Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

See our complete portfolio of awards below.

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Berkeley Dr. David H Raulet Transplantation Immunology Inactivating NK cell reactivity to facilitate transplantation of stem cell derived tissue $952,896
Stanford University Dr. Robert Negrin MD Transplantation Immunology Regulatory T cell induced tolerance to ESC transplantation $1,382,658
University of California, San Diego Prof. Martin Marsala Transplantation Immunology Induction of immune tolerance after spinal grafting of human ES-derived neural precursors $1,387,800
Cedars-Sinai Medical Center Dr. Terrence Town Transplantation Immunology Role of HLA in neural stem cell rejection using humanized mice $1,119,385
University of Southern California Dr. Terrence Christopher Town Transplantation Immunology Role of HLA in neural stem cell rejection using humanized mice $353,249
Stanford University Professor Christopher H. Contag Transplantation Immunology Engineering Embryonic Stem Cell Allografts for Operational Tolerance $1,411,338
University of California, San Diego Dr Yang Xu Transplantation Immunology Induction of immune tolerance to human embryonic stem cell-derived allografts $1,192,680
University of California, Los Angeles UCLA Gay Miriam Crooks Transplantation Immunology Engineering Thymic Regeneration to Induce Tolerance $1,235,445
University of California, Davis Dr. William J Murphy Transplantation Immunology Donor natural killer (NK) cells as “veto” cells to promote donor-specific tolerance $1,257,601
Palo Alto Veterans Institute for Research Dr. Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $733,061
Escape Therapeutics, Inc Basil M Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
La Jolla Institute for Immunology Dr. Anjana Rao Transplantation Immunology Generation of regulatory T cells by reprogramming $1,464,446
University of California, San Francisco Dr. Tippi C. MacKenzie Transplantation Immunology Maternal and Fetal Immune Responses to In Utero Hematopoietic Stem Cell Transplantation $1,230,869
Scripps Research Institute Dr. Jeanne F Loring Transplantation Immunology Thymus based tolerance to stem cell therapies $1,108,921
Stanford University Dr. Judith A Shizuru Transplantation Immunology Purified allogeneic hematopoietic stem cells as a platform for tolerance induction $1,233,275
University of California, San Francisco Dr. Jeffrey A Bluestone Transplantation Immunology Stem cell tolerance through the use of engineered antigen-specific regulatory T cells $1,152,768
University of California, San Francisco Dr. Mark S. Anderson Transplantation Immunology Stem cell differentiation to thymic epithelium for inducing tolerance to stem cells $1,314,089
University of California, San Diego Dr. Ying Liu Tools and Technologies I Generation of disease models for neurodegenerative disorders in hESCs by gene targeting $709,829
University of California, Davis Kit S Lam Tools and Technologies I Discovery of adhesion ligands for pluripotent human stem cells $834,003
ViaCyte, Inc. Dr. Evert J. Kroon Tools and Technologies I Development of the Theracyte Cellular Encapsulation System for Delivery of human ES Cell-derived Pancreatic Islets and Progenitors. $827,072
University of California, Irvine Dr. Lisa A Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
University of California, Berkeley Dr. Steven M. Conolly Tools and Technologies I Magnetic Particle Imaging: A Novel Ultra-sensitive Imaging Scanner for Tracking Stem Cells In Vivo $858,345
University of Southern California Dr. Pin Wang Tools and Technologies I Development of Baculoviral Vectors for Gene Editing of Human Stem Cells $945,604
Gamma Medica-Ideas, Inc. Douglas Jay Wagenaar Tools and Technologies I A Novel SPECT Microscopy System for 3D Imaging of Single Stem Cells In Vivo $800,065
University of California, Davis Dr. Alice F Tarantal Tools and Technologies I In Vivo Imaging for the Detection and Quantitation of Transplanted Stem/Progenitor Cells in Nonhuman Primates $799,350
University of California, Merced Dr. Michael Cleary Tools and Technologies I RNA Analysis by Biosynthetic Tagging (RABT): a tool for the identification of cell type-specific RNAs $481,096
Stanford University Professor Helen M. Blau PhD Tools and Technologies I Regulation of Stem Cell Fate in Bioengineered Arrays of Hydrogel Microwells $949,608
City of Hope, Beckman Research Institute Joseph D Gold Tools and Technologies I Development of Suspension Adaptation, Scale-up cGMP Banking and Cell Characterization Technologies for hESC Lines $882,929
Vala Sciences, Inc. Patrick McDonough Tools and Technologies I Optimization in the Identification, Selection and Induction of Maturation of Subtypes of Cardiomyocytes derived from Human Embryonic Stem Cells $870,717
University of California, Los Angeles Dr. Michael E. Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039
University of California, Irvine Dr. Orhan NALCIOGLU Tools and Technologies I A MULTI-MODALITY MOLECULAR IMAGING SYSTEM (MRSPECT) FOR IN VIVO STEM CELL TRACKING $719,798
Scripps Research Institute Dr. Jeanne F Loring Tools and Technologies I The Stem Cell Matrix: a map of the molecular pathways that define pluripotent cells $1,133,552
Scripps Research Institute Dr. Carlos F. Barbas Dr. Tools and Technologies I Development of a novel technology for precise, efficient, and safe genetic modification of stem cells $1,138,548
University of California, Santa Cruz Dr. Joel Alan Kubby Tools and Technologies I AO Wide-Field Microscope $549,551
University of California, San Diego Dr. Steven F Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
University of California, Santa Barbara Dr. Dennis O. Clegg Tools and Technologies I Synthetic Matrices for Stem Cell Growth and Differentiation $599,404
Fluidigm Corporation Dr. Marc A Unger Tools and Technologies I Scaleup of Versatile, Fully Automated, Microfluidic Cell Culture System $749,518
University of California, Los Angeles Dr. Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
VistaGen Therapeutics, Inc. Dr. Kristina Bonham Tools and Technologies I Development of an hES Cell-Based Assay System for Hepatocyte Differentiation Studies and Predictive Toxicology Drug Screening $971,558
University of California, Berkeley David Schaffer Tools and Technologies I Directed Evolution of Novel AAV Variants for Enhanced Gene Targeting in Pluripotent Human Stem Cells and Investigation of Dopaminergic Neuron Differentiation $918,000
Stanford University Dr. Katja Weinacht Preclinical Stage Projects Therapeutic Restoration of Immune Function through iPSC-derived Human Thymic Epithelial Cells $12,999,871
EVADE Therapeutics Sonja Schrepfer Preclinical Stage Projects Hypoimmune Stem Cell–Derived Islets: A Next-Generation Cell Therapy Toward a Functional Cure for Type 1 Diabetes $12,480,000
University of Southern California Charles Murry Preclinical Stage Projects Regenerating the Acutely Infarcted Heart with iPSC-Ventricular Cardiomyocytes. $6,891,118
University of California, Los Angeles Dr. Lili Yang Preclinical Stage Projects Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy for Multiple Sclerosis $7,499,996
Scribe Therapeutics Brett Staahl Preclinical Stage Projects A First-in-Class CIRSPR-CasX Gene Editing Therapy for Lowering Lp(a) to Prevent Cardiovascular Events $12,714,480
4D Molecular Therapeutics, Inc. Sara Collins Preclinical Stage Projects Gene Therapy for Alpha-1 Anti-Trypsin Deficiency $5,915,073
AcuraStem Incorporated Mr. Samuel V. Alworth MS, MBA Preclinical Stage Projects Late-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies $7,500,000
Cure Rare Disease Dr. Tahseen Mozaffar Preclinical Stage Projects Advancement of a myotropic, liver-detargeting therapy for LGMD2i/R9 $7,292,297
Scribe Therapeutics Brett Staahl Preclinical Stage Projects A first-in-class CRISPR-CasX gene editor silencing APOC3 transcription for the treatment of Severe Hypertriglyceridemia $13,000,000
Savanna Biotherapeutics, Inc. Dr. Sunil Gandhi Ph.D Preclinical Stage Projects Microglia replacement therapy for CSF1R-related Leukoencephalopathy $12,993,456
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