Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. 2011 J Hepatol
Equivalence of conventionally-derived and parthenote-derived human embryonic stem cells. 2011 PLoS One
Establishment of Human Trophoblast Progenitor Cell Lines from the Chorion. 2011 Stem Cells
Ets transcription factor Pointed promotes the generation of intermediate neural progenitors in Drosophila larval brains. 2011 Proc Natl Acad Sci U S A
Evidence That Gene Activation and Silencing during Stem Cell Differentiation Requires a Transcriptionally Paused Intermediate State. 2011 PLoS One
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. 2011 Nature
Evolving concepts in lung carcinogenesis. 2011 Semin Respir Crit Care Med
Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington’s disease affected neuronal cells for reduction of huntingtin. 2011 Mol Cell Neurosci
Exploiting bacterial peptide display technology to engineer biomaterials for neural stem cell culture. 2011 Biomaterials
Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions. 2011 Small Gtpases
Extensive determination of glycan heterogeneity reveals an unusual abundance of high-mannose glycans in enriched plasma membranes of human embryonic stem cells. 2011 Mol Cell Proteomics
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. 2011 Nat Biotechnol
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. 2011 Development
Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. 2011 Dev Biol
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. 2011 J Clin Invest
Feeder-dependent and feeder-independent iPS cell derivation from human and mouse adipose stem cells. 2011 Nat Protoc
FGF10 controls the patterning of the tracheal cartilage rings via Shh. 2011 Development
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. 2011 Mol Cell
FISH analysis of human pluripotent stem cells. 2011 Methods Mol Biol
From microRNAs to targets: pathway discovery in cell fate transitions. 2011 Curr Opin Genet Dev
Functional characterization of embryonic stem cell-derived endothelial cells. 2011 J Vasc Res
Functional Modules Distinguish Human Induced Pluripotent Stem Cells from Embryonic Stem Cells. 2011 Stem Cells Dev
Gene Editing of Human Embryonic Stem Cells via an Engineered Baculoviral Vector Carrying Zinc-finger Nucleases. 2011 Mol Ther
Gene targeting in human pluripotent stem cells. 2011 Methods Mol Biol
Generating gene knockout rats by homologous recombination in embryonic stem cells. 2011 Nat Protoc
Generation of HIV-1 Resistant and Functional Macrophages From Hematopoietic Stem Cell-derived Induced Pluripotent Stem Cells. 2011 Mol Ther
Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy. 2011 Proc Natl Acad Sci U S A
Genetic manipulations in the rat: progress and prospects. 2011 Curr Opin Nephrol Hypertens
Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-Sensitive Domain Changes in Differentiated Neurons. 2011 Stem Cells
Genetically Engineered Mesenchymal Stem Cells as a Proposed Therapeutic for Huntington’s Disease. 2011 Mol Neurobiol
Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. 2011 Cell Stem Cell
Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. 2011 Genes Dev
Genome-Wide Binding Map of the HIV-1 Tat Protein to the Human Genome. 2011 PLoS One
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. 2011 Nature
Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells. 2011 Mol Cell
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. 2011 Mol Cell
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. 2011 Nature
GROalpha regulates human embryonic stem cell self-renewal or adoption of a neuronal fate. 2011 Differentiation
Guided Migration of Neural Stem Cells Derived from Human Embryonic Stem Cells by an Electric Field. 2011 Stem Cells
Hand2 function in second heart field progenitors is essential for cardiogenesis. 2011 Dev Biol
HEB and E2A function as SMAD/FOXH1 cofactors. 2011 Genes Dev
Hedgehog and retinoic acid signaling cooperate to promote motoneurogenesis in zebrafish. 2011 Development
Hemogenic endothelium: origins, regulation, and implications for vascular biology. 2011 Semin Cell Dev Biol
High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs. 2011 J Vis Exp
Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration. 2011 J Virol Methods
Homologous recombination in human embryonic stem cells: a tool for advancing cell therapy and understanding and treating human disease. 2011 Clin Transl Sci
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. 2011 Nature
Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members. 2011 PLoS One
Human ESC-Derived Neural Crest Model Reveals a Key Role for SOX2 in Sensory Neurogenesis. 2011 Cell Stem Cell
Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. 2011 Hum Mol Genet