Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Signal transducer and activator of transcription 3 signaling as a potential target to treat muscle wasting diseases. 2016 Curr Opin Clin Nutr Metab Care
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. 2016 JCI Insight
Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. 2016 J Neurosci
Smooth Muscle Precursor Cells Derived from Human Pluripotent Stem Cells for Treatment of Stress Urinary Incontinence. 2016 Stem Cells Dev
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. 2016 Elife
SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73. 2016 Cell Signal
Spatial Variations in Vitreous Oxygen Consumption. 2016 PLoS One
Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. 2016 Dev Cell
Stem Cell Therapy in Nonneovascular Age-Related Macular Degeneration. 2016 Invest Ophthalmol Vis Sci
Stem cells and interspecies chimaeras. 2016 Nature
Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatan minipigs. 2016 Graefes Arch Clin Exp Ophthalmol
Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. 2016 Invest Ophthalmol Vis Sci
Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain. 2016 Biomaterials
Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair. 2016 Am J Respir Cell Mol Biol
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. 2016 Cold Spring Harb Symp Quant Biol
TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. 2016 Elife
Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. 2016 Nucleic Acids Res
The clinical applications of genome editing in HIV. 2016 Blood
The CRISPR Way to Think about Duchenne’s. 2016 N Engl J Med
The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. 2016 Cell Rep
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. 2016 Nat Commun
The tumorigenic potential of pluripotent stem cells: What can we do to minimize it? 2016 Bioessays
Thiol−ene Click Hydrogels for Therapeutic Delivery 2016 ACS Biomater. Sci. Eng.
Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. 2016 Cell Stem Cell
TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice. 2016 Gastroenterology
Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis. 2016 J Clin Invest
Transcriptome Encyclopedia of Early Human Development. 2016 Cell
Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro. 2016 Cell Stem Cell
Transplantation of human neural stem cells restores cognition in an immunodeficient rodent model of traumatic brain injury. 2016 Exp Neurol
Transplanted Human Stem Cell-Derived Interneuron Precursors Mitigate Mouse Bladder Dysfunction and Central Neuropathic Pain after Spinal Cord Injury. 2016 Cell Stem Cell
Tuning microenvironment modulus and biochemical composition promotes human mesenchymal stem cell tenogenic differentiation. 2016 J Biomed Mater Res A
Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development. 2016 PLoS One
Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice. 2016 Hepatology
Whole-genome mutational burden analysis of three pluripotency induction methods. 2016 Nat Commun
Wnt/beta-catenin and LIF-Stat3 signaling pathways converge on Sp5 to promote mouse embryonic stem cell self-renewal. 2016 J Cell Sci
YAP Induces Human Naive Pluripotency. 2016 Cell Rep
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cells. 2015 Bioorg Med Chem
A basal stem cell signature identifies aggressive prostate cancer phenotypes. 2015 Proc Natl Acad Sci U S A
A Continuous Molecular Roadmap to iPSC Reprogramming through Progression Analysis of Single-Cell Mass Cytometry. 2015 Cell Stem Cell
A functional genomics screen identifies an Importin-alpha homolog as a regulator of stem cell function and tissue patterning during planarian regeneration. 2015 BMC Genomics
A new notch for lung stem cells. 2015 Cell Stem Cell
A novel profibrotic mechanism mediated by TGFbeta-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells. 2015 J Pathol
A novel, long-lived, and highly engraftable immunodeficient mouse model of mucopolysaccharidosis type I. 2015 Mol Ther Methods Clin Dev
A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. 2015 Elife
A platform for rapid generation of single and multiplexed reporters in human iPSC lines. 2015 Sci Rep
A quantitative assessment of the content of hematopoietic stem cells in mouse and human endosteal-bone marrow: a simple and rapid method for the isolation of mouse central bone marrow. 2015 BMC Hematol
A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy. 2015 Stem Cell Reports
A specific E3 ligase/deubiquitinase pair modulates TBP protein levels during muscle differentiation. 2015 Elife
A survey of human brain transcriptome diversity at the single cell level. 2015 Proc Natl Acad Sci U S A