Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. 2016 Mol Ther Methods Clin Dev
Preclinical evaluation of mesenchymal stem cells overexpressing VEGF to treat critical limb ischemia. 2016 Mol Ther Methods Clin Dev
Preeclampsia and Inflammatory Preterm Labor Alter the Human Placental Hematopoietic Niche. 2016 Reprod Sci
Primary Cilium-Autophagy-Nrf2 (PAN) Axis Activation Commits Human Embryonic Stem Cells to a Neuroectoderm Fate. 2016 Cell
Programmable RNA Tracking in Live Cells with CRISPR/Cas9. 2016 Cell
Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy. 2016 Stem Cells Dev
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. 2016 Neuron
Rare SOX2+ Airway Progenitor Cells Generate KRT5+ Cells that Repopulate Damaged Alveolar Parenchyma following Influenza Virus Infection. 2016 Stem Cell Reports
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases. 2016 Mol Ther Nucleic Acids
Regenerating Perfection. 2016 J Ocul Pharmacol Ther
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy. 2016 N Engl J Med
Regulating Stem Cell Secretome Using Injectable Hydrogels with In Situ Network Formation. 2016 Adv Healthc Mater
Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. 2016 Cell
Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. 2016 PLoS One
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells. 2016 Mol Ther Nucleic Acids
Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells. 2016 Cell Rep
Rewinding the process of mammalian extinction. 2016 Zoo Biol
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. 2016 Nat Struct Mol Biol
ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium. 2016 Transl Vis Sci Technol
ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation. 2016 Stem Cell Res
RUNX1 prevents oestrogen-mediated AXIN1 suppression and beta-catenin activation in ER-positive breast cancer. 2016 Nat Commun
Same-Single-Cell Analysis of Pacemaker-Specific Markers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Subtypes Classified by Electrophysiology. 2016 Stem Cells
Selecting for neurogenic potential as an alternative for Alzheimer’s disease drug discovery. 2016 Alzheimers Dement
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells. 2016 Sci Transl Med
Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease. 2016 PLoS One
Signal transducer and activator of transcription 3 signaling as a potential target to treat muscle wasting diseases. 2016 Curr Opin Clin Nutr Metab Care
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. 2016 JCI Insight
Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. 2016 J Neurosci
Smooth Muscle Precursor Cells Derived from Human Pluripotent Stem Cells for Treatment of Stress Urinary Incontinence. 2016 Stem Cells Dev
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells. 2016 Elife
SOX2, OCT3/4 and NANOG expression and cellular plasticity in rare human somatic cells requires CD73. 2016 Cell Signal
Spatial Variations in Vitreous Oxygen Consumption. 2016 PLoS One
Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. 2016 Dev Cell
Stem Cell Therapy in Nonneovascular Age-Related Macular Degeneration. 2016 Invest Ophthalmol Vis Sci
Stem cells and interspecies chimaeras. 2016 Nature
Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatan minipigs. 2016 Graefes Arch Clin Exp Ophthalmol
Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. 2016 Invest Ophthalmol Vis Sci
Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain. 2016 Biomaterials
Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair. 2016 Am J Respir Cell Mol Biol
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. 2016 Cold Spring Harb Symp Quant Biol
TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. 2016 Elife
Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. 2016 Nucleic Acids Res
The clinical applications of genome editing in HIV. 2016 Blood
The CRISPR Way to Think about Duchenne’s. 2016 N Engl J Med
The Homeobox Transcription Factor RHOX10 Drives Mouse Spermatogonial Stem Cell Establishment. 2016 Cell Rep
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. 2016 Nat Commun
The tumorigenic potential of pluripotent stem cells: What can we do to minimize it? 2016 Bioessays
Thiol−ene Click Hydrogels for Therapeutic Delivery 2016 ACS Biomater. Sci. Eng.
Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. 2016 Cell Stem Cell
TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice. 2016 Gastroenterology