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A Chemical Approach to Stem Cell Biology

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  • Post published:May 8, 2025
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The aim of this project is to screen large collections of small molecules to identify molecules that allow one to propagate human embryonic stem cells (hESCs) in cell culture under…

Continue ReadingA Chemical Approach to Stem Cell Biology

Functions of RB family proteins in human embryonic stem cells

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  • Post published:May 8, 2025
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Nearly one out of every two Californians born today will develop cancer at some point in their lives, and it is likely that one in five persons will die of…

Continue ReadingFunctions of RB family proteins in human embryonic stem cells

Mapping the transcriptional regulatory elements in the genome of hESC

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  • Post published:May 8, 2025
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The human embryonic stem cells (hESC) have the remarkable potential to replicate themselves indefinitely and differentiate into virtually any cell type under appropriate environmental conditions. They accomplish this through regulating…

Continue ReadingMapping the transcriptional regulatory elements in the genome of hESC

Stem Cell Survival and Differentiation Through Chemical Genetics

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  • Post published:May 8, 2025
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This project will test the effects of chemical compounds similar to conventional pills for their abilities to keep human embryonic stem cells growing and multiplying in the laboratory or to…

Continue ReadingStem Cell Survival and Differentiation Through Chemical Genetics

Regulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling

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  • Post published:May 8, 2025
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Human ES cells can be used to make healthy neurons to replace the cells that are lost in neurological diseases such as Alzheimer’s and Parkinson’s diseases. This holds great hope…

Continue ReadingRegulation of human neural progenitor cell proliferation by Ryk-mediated Wnt signaling

Generation of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells

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  • Post published:May 8, 2025
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For many therapeutic reasons it is important to have available large numbers of blood cells. However, it is difficult to generate large numbers of specialized blood cells that have the…

Continue ReadingGeneration of long-term cultures of human hematopoietic multipotent progenitors from embryonic stem cells

hESC as tools to investigate the neural crest origin of Ewing’s sarcoma

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  • Post published:May 8, 2025
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Human embryonic stem cells (hESC) hold great promise as sources of tissue for regenerative medicine and therapeutics. In addition, their utility as tools to study the origins and biology of…

Continue ReadinghESC as tools to investigate the neural crest origin of Ewing’s sarcoma

Differentiation of Human Embryonic Stem Cells to Intestinal Fates

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  • Post published:May 8, 2025
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The roughly 25 feet of intestine in the adult human play numerous essential roles in daily life, such as nutrient absorption, secretion of hormones, and serving as a barrier to…

Continue ReadingDifferentiation of Human Embryonic Stem Cells to Intestinal Fates

Micro Platform for Controlled Cardiac Myocyte Differentiation

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  • Post published:May 8, 2025
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Congestive heart failure, the inability of the heart to continue to pump effectively due to damage of its muscle cells, affects approximately 4.8 million Americans and is a leading cause…

Continue ReadingMicro Platform for Controlled Cardiac Myocyte Differentiation

Micro Platform for Controlled Cardiac Myocyte Differentiation

  • Post author:
  • Post published:May 8, 2025
  • Post category:

Congestive heart failure, the inability of the heart to continue to pump effectively due to damage of its muscle cells, affects approximately 4.8 million Americans and is a leading cause…

Continue ReadingMicro Platform for Controlled Cardiac Myocyte Differentiation
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