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MicroRNA Regulation in Stem Cells, Development, and Disease

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  • Post published:June 30, 2025
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Pluripotent embryonic stem cells (ESCs) have the remarkable capacity to differentiate into any specialized cell type in the human body and are therefore of potential therapeutic value for neurodegenerative diseases,…

Continue ReadingMicroRNA Regulation in Stem Cells, Development, and Disease

Generation of functional cells and organs from iPSCs

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  • Post published:June 30, 2025
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The development of induced pluripotent stem cell (iPSC) technology may be the most important advance in stem cell biology for the future of medicine. This technology allows one to generate…

Continue ReadingGeneration of functional cells and organs from iPSCs

Engineering Cardiac Tissue for Regeneration and Drug Development

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  • Post published:June 30, 2025
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The ‘valley of death’ in scientific parlance refers to the time period where biomedical discovery in the laboratory fails to result in a cure for a disease. While the last…

Continue ReadingEngineering Cardiac Tissue for Regeneration and Drug Development

Epithelial progenitors and the stromal niche as therapeutic targets in lung disease

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  • Post published:June 30, 2025
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Chronic lung disease is an enormous societal and medical problem in California and the nation as a whole, representing the third most likely cause of death. Treatment costs were $389.2…

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Repair and regeneration of the nephron

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  • Post published:June 30, 2025
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Kidney function is essential for removing the wastes that result from normal cell function and maintaining water and salt balance in our internal tissues. These actions are carried out by…

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Stem Cell Pathologies in Parkinson’s disease as a key to Regenerative Strategies

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  • Post published:June 30, 2025
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Protection and cell repair strategies for neurodegenerative diseases such as Parkinson’s Disease (“PD”) depend on well-characterized candidate human stem cells that are robust and show promise for generating the neurons…

Continue ReadingStem Cell Pathologies in Parkinson’s disease as a key to Regenerative Strategies

Development of Cellular Therapies for Retinal Disease

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  • Post published:June 30, 2025
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The long term goal of our research program is regeneration of the diseased eye. Age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa are leading causes of blindness for which there…

Continue ReadingDevelopment of Cellular Therapies for Retinal Disease

Developing a regeneration-based functional restoration treatment for spinal cord injury

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  • Post published:June 30, 2025
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One of the most exciting and challenging frontiers in neuroscience and medicine is to repair traumatic injuries to the central nervous system (CNS). Most spinal cord and head injuries result…

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The role of neural stem cells in cerebellar development, regeneration and tumorigenesis

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  • Post published:June 30, 2025
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Stem cells have the remarkable ability to renew themselves and to generate multiple different cell types. This allows them to generate normal tissues during development and to repair tissues following…

Continue ReadingThe role of neural stem cells in cerebellar development, regeneration and tumorigenesis

Medical School Loan Repayment Program

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  • Post published:June 30, 2025
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Congenital and acquired defects of cardiac pacemakers are leading causes of morbidity and mortality in our society. Dysfunctions of the SA node and the lower conduction cells lead to a…

Continue ReadingMedical School Loan Repayment Program
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