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Grant Award Details
Gladstone CIRM Scholar Program
Grant Type:
Training Grant I-2
Grant Number:
T2-00003
Investigator:
Name:
Robert Mahley
Institution:
Gladstone Institutes, J. David
Type:
PI
Award Value:
$2,192,073
Status:
Closed
Grant Application Details
Application Title:
Gladstone CIRM Scholar Program
Public Abstract:
Statement of Benefit to California:
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Publications
Methods Enzymol
(2012)
High-throughput screening in primary neurons.
(PubMed:
22341232
)
Circ Res
(2012)
miR-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting VEGF Signaling.
(PubMed:
22955733
)
Stem Cell Res Ther
(2011)
Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice.
(PubMed:
21375737
)
Cell Stem Cell
(2010)
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors.
(PubMed:
20362537
)
J Bone Miner Res
(2010)
Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation.
(PubMed:
20200944
)
Cell
(2010)
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.
(PubMed:
20691899
)
Proc Natl Acad Sci U S A
(2010)
skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration.
(PubMed:
21071677
)
Aging (Albany NY)
(2010)
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.
(PubMed:
20634564
)
Curr Opin Neurobiol
(2009)
High-content screening of primary neurons: ready for prime time.
(PubMed:
19889533
)
Nat Cell Biol
(2009)
A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.
(PubMed:
19620969
)
Nature
(2009)
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity.
(PubMed:
19578358
)
Dev Cell
(2009)
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling.
(PubMed:
19217425
)
Cell Stem Cell
(2009)
GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice.
(PubMed:
19951691
)
BMB Rep
(2008)
ESCRT, autophagy, and frontotemporal dementia.
(PubMed:
19123971
)
Autophagy
(2008)
Roles of ESCRT in autophagy-associated neurodegeneration.
(PubMed:
18094607
)
J Clin Invest
(2008)
Regulation of Abeta pathology by beclin 1: a protective role for autophagy?
(PubMed:
18497881
)
Cell Cycle
(2008)
Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis.
(PubMed:
19066459
)
Proc Natl Acad Sci U S A
(2008)
microRNA-138 modulates cardiac patterning during embryonic development.
(PubMed:
19004786
)
Dev Cell
(2008)
miR-126 regulates angiogenic signaling and vascular integrity.
(PubMed:
18694566
)
Cell Stem Cell
(2008)
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells.
(PubMed:
18371447
)
Nat Methods
(2008)
Engineering GPCR signaling pathways with RASSLs.
(PubMed:
18668035
)
PLoS One
(2008)
Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter.
(PubMed:
18596956
)
Proc Natl Acad Sci U S A
(2008)
Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass.
(PubMed:
18212126
)
Oncogene
(2007)
Sirtuins: critical regulators at the crossroads between cancer and aging.
(PubMed:
17694089
)
Curr Biol
(2007)
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration.
(PubMed:
17683935
)
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