Gladstone CIRM Scholar Program

Return to Grants

Grant Award Details

Grant Application Details

Publications

• Dev Cell (2009): Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. (PubMed: 19217425)
• Stem Cell Res Ther (2011): Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice. (PubMed: 21375737)
• Trends Biochem Sci (2007): A developmental view of microRNA function. (PubMed: 17350266)
• Cell (2010): Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. (PubMed: 20691899)
• Cell (2007): Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. (PubMed: 17397913)
• Nat Methods (2008): Engineering GPCR signaling pathways with RASSLs. (PubMed: 18668035)
• BMB Rep (2008): ESCRT, autophagy, and frontotemporal dementia. (PubMed: 19123971)
• Curr Biol (2007): ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration. (PubMed: 17683935)
• Cell Stem Cell (2009): GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice. (PubMed: 19951691)
• Proc Natl Acad Sci U S A (2007): Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation. (PubMed: 17485678)
• J Bone Miner Res (2010): Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation. (PubMed: 20200944)
• Curr Opin Neurobiol (2009): High-content screening of primary neurons: ready for prime time. (PubMed: 19889533)
• Methods Enzymol (2012): High-throughput screening in primary neurons. (PubMed: 22341232)
• PLoS One (2008): Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter. (PubMed: 18596956)
• Proc Natl Acad Sci U S A (2008): microRNA-138 modulates cardiac patterning during embryonic development. (PubMed: 19004786)
• Cell Stem Cell (2010): MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. (PubMed: 20362537)
• Cell Stem Cell (2008): MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. (PubMed: 18371447)
• Circ Res (2012): miR-10 Regulates the Angiogenic Behavior of Zebrafish and Human Endothelial Cells by Promoting VEGF Signaling. (PubMed: 22955733)
• Dev Cell (2008): miR-126 regulates angiogenic signaling and vascular integrity. (PubMed: 18694566)
• Nature (2009): miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. (PubMed: 19578358)
• Aging (Albany NY) (2010): miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. (PubMed: 20634564)
• PLoS One (2007): Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor. (PubMed: 18338032)
• Proc Natl Acad Sci U S A (2008): Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass. (PubMed: 18212126)
• Nature (2006): Potential of stem-cell-based therapies for heart disease. (PubMed: 16810246)
• J Clin Invest (2008): Regulation of Abeta pathology by beclin 1: a protective role for autophagy? (PubMed: 18497881)
• Nat Cell Biol (2009): A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate. (PubMed: 19620969)
• Autophagy (2008): Roles of ESCRT in autophagy-associated neurodegeneration. (PubMed: 18094607)
• Oncogene (2007): Sirtuins: critical regulators at the crossroads between cancer and aging. (PubMed: 17694089)
• Proc Natl Acad Sci U S A (2010): skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration. (PubMed: 21071677)
• Cell Cycle (2008): Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis. (PubMed: 19066459)