Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Modeling neuro-immune interactions during Zika virus infection. 2017 Hum Mol Genet
Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation. 2017 Cell Stem Cell
Modeling Williams syndrome with induced pluripotent stem cells. 2017 Neurogenesis (Austin)
Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome. 2017 Brain
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. 2017 Proc Natl Acad Sci U S A
Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion. 2017 JCI Insight
Multi-scale tracking reveals scale-dependent chromatin dynamics after DNA damage. 2017 Mol Biol Cell
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. 2017 Elife
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates. 2017 Nature
Nanofibre optic force transducers with sub-piconewton resolution via near-field plasmon-dielectric interactions. 2017 Nat Photonics
Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine. 2017 Stem Cell Reports
Neural Precursor-Derived Pleiotrophin Mediates Subventricular Zone Invasion by Glioma. 2017 Cell
Neutrophils Induce Astroglial Differentiation and Migration of Human Neural Stem Cells via C1q and C3a Synthesis. 2017 J Immunol
New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells. 2017 Stem Cells
Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart. 2017 Sci Rep
Paracrine regulation of normal and malignant hematopoiesis. 2017 Curr Opin Hematol
Phase separation drives heterochromatin domain formation. 2017 Nature
Placental mesenchymal stromal cells seeded on clinical grade extracellular matrix improve ambulation in ovine myelomeningocele. 2017 J Pediatr Surg
Porcine neural progenitor cells derived from tissue at different gestational ages can be distinguished by global transcriptome. 2017 Cell Transplant
Potential clinical applications of placental stem cells for use in fetal therapy of birth defects. 2017 Placenta
Preclinical studies for a phase 1 clinical trial of autologous hematopoietic stem cell gene therapy for sickle cell disease. 2017 Cytotherapy
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis. 2017 Proc Natl Acad Sci U S A
Prognostic Significance of Left Ventricular Fibrosis in Patients With Congenital Bicuspid Aortic Valve. 2017 Am J Cardiol
Reliable Identification of Living Dopaminergic Neurons in Midbrain Cultures Using RNA Sequencing and TH-promoter-driven eGFP Expression. 2017 J Vis Exp
Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells. 2017 Stem Cells Transl Med
Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis. 2017 Sci Rep
Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear. 2017 Sci Rep
Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis. 2017 Elife
RNA editing-dependent epitranscriptome diversity in cancer stem cells. 2017 Nat Rev Cancer
Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. 2017 Cell Rep
SERS-enhanced piezoplasmonic graphene composite for biological and structural strain mapping. 2017 Nanoscale
Simultaneous, label-free, multispectral fluorescence lifetime imaging and optical coherence tomography using a double-clad fiber. 2017 Opt Lett
Sin3a regulates epithelial progenitor cell fate during lung development. 2017 Development
Single Cell Gene Expression Profiling of Skeletal Muscle-Derived Cells. 2017 Methods Mol Biol
Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns. 2017 Cell
Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma. 2017 Cell Rep
SLC7A11 Overexpression in Glioblastoma Is Associated with Increased Cancer Stem Cell-Like Properties. 2017 Stem Cells Dev
Smek promotes corticogenesis through regulating Mbd3’s stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis. 2017 PLoS Biol
Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis. 2017 Proc Natl Acad Sci U S A
Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex. 2017 Science
Spontaneous Single-Copy Loss of TP53 in Human Embryonic Stem Cells Markedly Increases Cell Proliferation and Survival. 2017 Stem Cells
Susceptibility-Weighted Imaging Identifies Iron-Oxide-Labeled Human Neural Stem Cells: Automated Computational Detection. 2017 Dev Neurosci
Synthetic Route Development for the Laboratory Preparation of Eupalinilide E. 2017 J Org Chem
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. 2017 Nat Commun
Systemic delivery of factor IX messenger RNA for protein replacement therapy. 2017 Proc Natl Acad Sci U S A
Systemic Neutrophil Depletion Modulates the Migration and Fate of Transplanted Human Neural Stem Cells to Rescue Functional Repair. 2017 J Neurosci
Targeted chromatin ligation, a robust epigenetic profiling technique for small cell numbers. 2017 Nucleic Acids Res
Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma. 2017 Nature
The Diverse Roles of Hydrogel Mechanics in Injectable Stem Cell Transplantation. 2017 Curr Opin Chem Eng
The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome. 2017 Clin Epigenetics