This project will establish an open-source network to share new cellular engineering platforms across manufacturing facilities; expand our non-viral engineering approaches to improve product safety and efficacy; and formalize our…
The project aims to provide tools & strategies to improve cell therapy manufacturing through collaborations, increase availability of viral vectors, train & educate underrepresented students, standardize data collection in academic…
The Stanford LCGM supports process development and manufacturing for investigator initiated and select industry partner clinical trials. The objective of our proposal is to complete our project plan and enhance…
We aim to considerably expand access for all Californians to outstanding cell and gene therapy treatments for multiple patients. With operational enhancements to develop diverse talent from underserved communities, our…
To contribute to a network that will de-risk pathways to commercialization for cell and gene therapies and develop a diverse and skilled manufacturing workforce in California, we propose to develop…
The project plan outlines key operational enhancements, development of specialization areas, and support for new workforce development initiatives that will enable our GMP cell manufacturing facility be a key component…
Research Objective 1.- Develop a better chronic pain in vitro model using iPSC-derived nociceptors. 2.- Understand the Mechanism of Action behind Chronic Pain Nociception. 3.- Attributes to establish a robust…
Research Objective To integrate emulsion microfluidics-based encapsulation with AI-powered imaging to develop a high-throughput pipeline for stem cell-based embryo models. Impact We will overcome key bottlenecks to drive breakthroughs in…
Research Objective To utilize human iPSCs as an in vitro model of hearing loss and overcome obstacles to hair cell regeneration by prompting post-mitotic supporting cells to re-enter the cell…
Research Objective A complete methodology for high efficiency, minimal toxicity hematopoietic stem cell transplantation for treatment of pediatric neurodegenerative disorders. Impact Improve treatment and outcomes for patients with neurodegenerative disorders…
