Sheng Ding
Institution Name:
Gladstone Institutes, J. David
Total Awards:
5
Award Value:
$6,402,014
Awards as PI
| Program Type | Institution | Grant Title | Award Value |
|---|---|---|---|
| New Cell Lines | Gladstone Institutes, J. David | Derivation of New ICM-stage hESCs | $778,859 |
| New Faculty I | Gladstone Institutes, J. David | Reprogramming of human somatic cells back to pluripotent embryonic stem cells | $1,320,101 |
| Basic Biology IV | Gladstone Institutes, J. David | A new paradigm of lineage-specific reprogramming | $1,568,395 |
| Basic Biology V | Gladstone Institutes, J. David | A novel druggable mechanism to safeguard stem cell genome | $1,294,495 |
| Shared Labs | Scripps Research Institute | TSRI Center for hESC Research | $1,440,164 |
Total: $6,402,014.00 |
Publications
- Nature 2008 A chemical approach to stem-cell biology and regenerative medicine. (PubMed: 18480815)
- J Biol Chem 2010 Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules. (PubMed: 20705612)
- Sci Prog 2011 Development unchained: how cellular reprogramming is redefining our view of cell fate and identity. (PubMed: 22026150)
- Stem Cells 2009 Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2. (PubMed: 19839055)
- Nat Chem Biol 2010 Metabolic oxidation regulates embryonic stem cell differentiation. (PubMed: 20436487)
- Cell Stem Cell 2010 Reprogramming of human primary somatic cells by OCT4 and chemical compounds. (PubMed: 21112560)
- Curr Opin Cell Biol 2012 Cellular reprogramming: a small molecule perspective. (PubMed: 22959962)
- Circ Res 2013 Progress in the reprogramming of somatic cells. (PubMed: 23371904)
- J Cell Sci 2012 Small molecules, big roles - the chemical manipulation of stem cell fate and somatic cell reprogramming. (PubMed: 23420199)
- Stem Cells Transl Med 2013 Concise Review: Chemical Approaches for Modulating Lineage-Specific Stem Cells and Progenitors. (PubMed: 23580542)
- Cell Stem Cell 2013 Chemical approaches to stem cell biology and therapeutics. (PubMed: 24012368)
- Cell Rep 2014 Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. (PubMed: 24561253)
- Science 2016 Conversion of human fibroblasts into functional cardiomyocytes by small molecules. (PubMed: 27127239)