Ophir Klein
Institution Name:
University of California, San Francisco
Total Awards:
4
Award Value:
$6,103,764
Awards as PI
Publications
- Development 2010 Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. (PubMed: 20978073)
- Development 2010 Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. (PubMed: 20978072)
- Development 2011 Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. (PubMed: 21862563)
- Nat Cell Biol 2013 BMI1 represses Ink4a/Arf and Hox genes to regulate stem cells in the rodent incisor. (PubMed: 23728424)
- Sci Rep 2013 Sprouty genes regulate proliferation and survival of human embryonic stem cells. (PubMed: 23880645)
- Cell Rep 2015 Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. (PubMed: 25818302)
- Stem Cell Reports 2015 Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo. (PubMed: 26050928)
- JCI Insight 2016 Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. (PubMed: 27525310)
- Development 2017 In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development. (PubMed: 27927684)
- Nature 2018 Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. (PubMed: 29950724)
- Sci China Life Sci 2018 The intestinal epithelial response to damage. (PubMed: 30194677)
- Nat Commun 2018 LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. (PubMed: 30305617)
- EMBO J 2019 Atoh1(+) secretory progenitors possess renewal capacity independent of Lgr5(+) cells during colonic regeneration. (PubMed: 30635334)
