Mana Parast
Institution Name:
University of California, San Diego
Total Awards:
2
Award Value:
$6,052,668
Awards as PI
Program Type | Institution | Grant Title | Award Value |
---|---|---|---|
New Faculty II | University of California, San Diego | Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal | $3,077,918 |
New Faculty Physician Scientist | University of California, San Diego | Human pluripotent stem cell-based therapeutics for preeclampsia | $2,974,750 |
Total: $6,052,668.00 |
Publications
- Cell Stem Cell 2012 Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. (PubMed: 22560082)
- J Invest Dermatol 2013 Melanocytes derived from transgene-free human induced pluripotent stem cells. (PubMed: 23514962)
- Development 2013 BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a DeltaNp63+ cytotrophoblast stem cell state. (PubMed: 24004950)
- Am J Pathol 2014 p63 inhibits extravillous trophoblast migration and maintains cells in a cytotrophoblast stem cell-like state. (PubMed: 25307348)
- Int J Dev Biol 2014 BMP4 regulation of human trophoblast development. (PubMed: 25023690)
- Placenta 2015 MTA3 regulates differentiation of human cytotrophoblast stem cells. (PubMed: 26198267)
- Proc Natl Acad Sci U S A 2016 Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. (PubMed: 27325764)
- Am J Pathol 2017 Hypoxia Directs Human Extravillous Trophoblast Differentiation in a Hypoxia-Inducible Factor-Dependent Manner. (PubMed: 28167044)
- Placenta 2017 Human trophoblast stem cells: Real or not real? (PubMed: 28087122)
- J Endocrinol 2018 Trophoblast lineage specification, differentiation and their regulation by oxygen tension. (PubMed: 29259074)
- Development 2018 Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. (PubMed: 29361559)
- Curr Protoc Stem Cell Biol 2019 An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. (PubMed: 31479595)
- Sci Rep 2021 Modeling preeclampsia using human induced pluripotent stem cells. (PubMed: 33723311)