Holger Willenbring
Institution Name:
University of California, San Francisco
Total Awards:
5
Award Value:
$6,550,272
Awards as PI
Awards as Co-PI
Early Translational II | Liver Cell Transplantation |
Publications
- Cell Stem Cell 2007 On the origin of the term "stem cell". (PubMed: 18371332)
- J Clin Invest 2012 A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. (PubMed: 22326957)
- Hepatology 2010 MicroRNAs control hepatocyte proliferation during liver regeneration. (PubMed: 20432256)
- Aging (Albany NY) 2010 miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. (PubMed: 20634564)
- J Clin Invest 2010 Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. (PubMed: 20739754)
- Proc Natl Acad Sci U S A 2011 Core promoter recognition complex changes accompany liver development. (PubMed: 21368148)
- Stem Cell Res 2010 Transplanted nonviable human hepatocytes produce appreciable serum albumin levels in mice. (PubMed: 20829142)
- Cell Stem Cell 2011 A simple code for installing hepatocyte function. (PubMed: 21816357)
- J Clin Invest 2012 Cholangiocarcinomas can originate from hepatocytes in mice. (PubMed: 22797301)
- Nature 2014 Mouse liver repopulation with hepatocytes generated from human fibroblasts. (PubMed: 24572354)
- Cell Rep 2014 Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury. (PubMed: 25131204)
- Hepatology 2016 Assessing the therapeutic potential of lab-made hepatocytes. (PubMed: 27014802)
- Cell Stem Cell 2016 In Vivo Hepatic Reprogramming of Myofibroblasts with AAV Vectors as a Therapeutic Strategy for Liver Fibrosis. (PubMed: 27257763)
- Nature 2018 De novo formation of the biliary system by TGFbeta-mediated hepatocyte transdifferentiation. (PubMed: 29720662)