Publications

• Stem Cell Reports 2015 A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy. (PubMed: 26321144)
• Development 2015 Interspecific in vitro assay for the chimera-forming ability of human pluripotent stem cells. (PubMed: 26023098)
• Nature 2016 Stem cells and interspecies chimaeras. (PubMed: 27905428)
• Nature 2017 Interspecies organogenesis generates autologous functional islets. (PubMed: 28117444)
• Cell Stem Cell 2016 Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. (PubMed: 27814480)
• Cell Syst 2017 Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity. (PubMed: 29073372)
• Stem Cell Reports 2017 An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. (PubMed: 28238792)
• Dev Cell 2016 Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. (PubMed: 27404362)
• Cell Stem Cell 2018 iPSC-Derived Organs In Vivo: Challenges and Promise. (PubMed: 29304339)
• Annu Rev Cell Dev Biol 2017 Lessons from Interspecies Mammalian Chimeras. (PubMed: 28806099)
• Cell Stem Cell 2018 Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. (PubMed: 29625072)
• Sci Rep 2017 CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. (PubMed: 29234093)
• Stem Cell Reports 2017 In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma. (PubMed: 28943250)
• Stem Cell Reports 2018 Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications. (PubMed: 29478892)
• Cell Stem Cell 2018 Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress. (PubMed: 29706577)
• Curr Opin Genet Dev 2018 Interspecies chimeras. (PubMed: 29859382)
• ACS Synth Biol 2018 Designing Motif-Engineered Receptors To Elucidate Signaling Molecules Important for Proliferation of Hematopoietic Stem Cells. (PubMed: 29920201)
• J Hepatol 2018 Chimeric liver transplantation reveals interspecific graft remodelling. (PubMed: 30031887)
• Biomaterials 2018 Human iPS derived progenitors bioengineered into liver organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold. (PubMed: 30149262)
• Stem Cell Reports 2018 Generation of Vascular Endothelial Cells and Hematopoietic Cells by Blastocyst Complementation. (PubMed: 30245211)
• Transgenic Res 2018 Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep. (PubMed: 30284144)
• Sci Rep 2018 An interspecies barrier to tetraploid complementation and chimera formation. (PubMed: 30327488)
• Sci Rep 2018 Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate. (PubMed: 30367142)
• Cell Rep 2018 Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. (PubMed: 30380403)
• iScience 2018 Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector. (PubMed: 30447647)
• Science 2018 Changing concepts in hematopoietic stem cells. (PubMed: 30467158)
• Nat Methods 2018 Efficient scarless genome editing in human pluripotent stem cells. (PubMed: 30504872)
• Exp Hematol 2018 Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity. (PubMed: 29705267)
• Science 2016 Depleting dietary valine permits nonmyeloablative mouse hematopoietic stem cell transplantation. (PubMed: 27934766)
• Methods Mol Biol 2019 Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. (PubMed: 30649763)
• Nat Commun 2019 Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. (PubMed: 30723213)
• Sci Rep 2019 LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. (PubMed: 30765795)
• Cell Stem Cell 2019 Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. (PubMed: 31051134)
• Nature 2019 Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. (PubMed: 31142833)
• Nat Protoc 2020 Long-term ex vivo expansion of mouse hematopoietic stem cells. (PubMed: 31915389)
• Exp Hematol 2019 Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. (PubMed: 31874780)
• Development 2019 Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. (PubMed: 31371526)
• Methods Mol Biol 2019 Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking. (PubMed: 31396943)
• Methods Mol Biol 2019 Human iPSC Generation from Antigen-Specific T Cells. (PubMed: 31396928)
• Haematologica 2020 Long-term eradication of extranodal natural killer/T-cell lymphoma, nasal type, by induced pluripotent stem cell-derived Epstein-Barr virus-specific rejuvenated T cells in vivo. (PubMed: 31296577)
• Development 2020 Germline development in rat revealed by visualization and deletion of Prdm14. (PubMed: 32001439)
• Stem Cell Reports 2020 Compensation of Disabled Organogeneses in Genetically Modified Pig Fetuses by Blastocyst Complementation. (PubMed: 31883918)
• Nat Med 2019 Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. (PubMed: 31700187)
• Nat Commun 2019 Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors. (PubMed: 31350390)
• Sci Rep 2019 Anephrogenic phenotype induced by SALL1 gene knockout in pigs. (PubMed: 31142767)