Pro-healing biomaterial for treating lung inflammation associated with COVID-19
Grant Award Details
Grant Type:
Grant Number:
DISC2COVID19-12007
Investigator(s):
Disease Focus:
Human Stem Cell Use:
Award Value:
$221,758
Status:
Closed
Progress Reports
Reporting Period:
Year 1 plus NCE
Grant Application Details
Application Title:
Pro-healing biomaterial for treating lung inflammation associated with COVID-19
Public Abstract:
Research Objective
Pro-healing biomaterial to treat lung inflammation and promote recovery.
Impact
COVID-19 associated acute respiratory distress syndrome
Major Proposed Activities
Pro-healing biomaterial to treat lung inflammation and promote recovery.
Impact
COVID-19 associated acute respiratory distress syndrome
Major Proposed Activities
- Evaluate biomaterial for ability to reduce lung inflammation in rodent model
- Evaluate biomaterial for ability to recruit stem cells in the lung
- Evaluate biomaterial for ability to improve lung function in rodent model
- Evaluate biomaterial for ability to recruit human stem cells
Statement of Benefit to California:
In late-June 2020, there are more than 5,700 Californians who are currently hospitalized because of COVID-19 (tested positive or suspected) with over 1,300 confirmed COVID-19 patients in the ICU. A significant number of severe cases involve a negative inflammatory response in the lungs leading to respiratory failure. We aim to develop a new therapeutic that can treat this inflammation and promote lung healing thereby having potential benefit to thousands of Californians.
