In neurons and beyond: how protein interactions shape the cellular response to Huntington’s Disease
Grant Award Details
Grant Type:
Grant Number:
DISC0-17566
Investigator(s):
Award Value:
$2,056,195
Status:
Pre-Active
Grant Application Details
Application Title:
In neurons and beyond: how protein interactions shape the cellular response to Huntington's Disease
Public Abstract:
Research Objective
New knowledge relating to protein-protein interactions that drive vulnerability of different cell types to neurodegeneration disease mutations using Huntington's disease as a paradigm.
Impact
The studies will inform current gaps in knowledge about drivers of cell-type specific functions of Huntington and cell vulnerability in Huntington’s disease and other neurodegenerative diseases.
New knowledge relating to protein-protein interactions that drive vulnerability of different cell types to neurodegeneration disease mutations using Huntington's disease as a paradigm.
Impact
The studies will inform current gaps in knowledge about drivers of cell-type specific functions of Huntington and cell vulnerability in Huntington’s disease and other neurodegenerative diseases.