Autologous therapy for Parkinson’s disease: single cell RNAseq for in depth characterization of transplanted cells

We have completed experiments to track the development of dopamine neurons from iPSCs using single cell RNA sequencing. These data have been integrated into a bioinformatic tool, NeuroTest, that will be used to help us evaluate the quality of the patient-specific dopamine neuron replacement therapy that we are developing for Parkinson Disease.