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Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer

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  • Post published:November 14, 2025
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Stem cell quality and safety in developing regenerative medicine therapies is of utmost importance. Poor outcomes include inadequate functionality, exhaustion, immune rejection, cancer development, and others. Recent studies strongly support…

Continue ReadingMitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer

The stem cell microenvironment in the maintenance of pluripotency and reprogramming

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  • Post published:November 14, 2025
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Pluripotent stem cell research is just on the verge of beginning to fulfill its promise to revolutionize medicine. Whether they are derived from embryos, or from adult cells that have…

Continue ReadingThe stem cell microenvironment in the maintenance of pluripotency and reprogramming

Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons

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  • Post published:November 14, 2025
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One of the main objectives of stem cell biology is to create physiologically relevant cell types that can be used to either facilitate the study of or directly treat human…

Continue ReadingMolecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons

Defining the molecular mechanisms of somatic cell reprogramming

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  • Post published:November 14, 2025
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The development of methods to “reprogram” adult cells such as skin cells by simultaneously expressing four specific factors — Oct3/4, Sox2, c-Myc and Klf4 — in order to create cells…

Continue ReadingDefining the molecular mechanisms of somatic cell reprogramming

Molecular Mechanisms of Reprogramming towards Pluripotency

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  • Post published:November 14, 2025
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Stem cell biology and its applications to cell-based therapies, since its inception 30 years ago, has been hindered by the immunological considerations of rejection of non-autologous cells in patients, as…

Continue ReadingMolecular Mechanisms of Reprogramming towards Pluripotency

Safety “Clinical Trial” of the Cardiac Liability of COVID19 Polytherapy

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  • Post published:September 12, 2024
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Continue ReadingSafety “Clinical Trial” of the Cardiac Liability of COVID19 Polytherapy

Autologous therapy for Parkinson’s disease: single cell RNAseq for in depth characterization of transplanted cells

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  • Post published:September 12, 2024
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Continue ReadingAutologous therapy for Parkinson’s disease: single cell RNAseq for in depth characterization of transplanted cells
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