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RNA Analysis by Biosynthetic Tagging (RABT): a tool for the identification of cell type-specific RNAs

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  • Post published:May 20, 2025
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Advancing our understanding of stem cell biology often relies on answers to the following types of questions: What are the differences in gene expression between a stem cell and the…

Continue ReadingRNA Analysis by Biosynthetic Tagging (RABT): a tool for the identification of cell type-specific RNAs

Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells

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  • Post published:May 20, 2025
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Cancer is the leading cause of death for people younger than 85. High cancer mortality rates related to resistance to therapy and malignant progression underscore the need for more sensitive…

Continue ReadingDerivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells

Stem Cells in Lung Cancer

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  • Post published:May 20, 2025
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Lung cancer is the most deadly cancer worldwide and accounts for more deaths than prostate cancer, breast cancer and colon cancer combined. Non small cell lung cancer (NSCLC) accounts for…

Continue ReadingStem Cells in Lung Cancer

Derivation and Characterization of Cancer Stem Cells from Human ES Cells

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  • Post published:May 20, 2025
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Cancer is the leading cause of death for people younger than 85 (1). High cancer mortality rates underscore the need for more sensitive diagnostic techniques as well as therapies that…

Continue ReadingDerivation and Characterization of Cancer Stem Cells from Human ES Cells

Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

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  • Post published:May 20, 2025
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Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that is rapidly fatal within months if untreated. Even with aggressive treatment, including chemotherapy and bone marrow…

Continue ReadingDevelopment of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors

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  • Post published:May 20, 2025
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Cancer is a major cause of human death worldwide. The vast majority of cancer patients suffer from solid tumors whose growth destroys vital organs. We propose to develop novel therapeutic…

Continue ReadingTherapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors

Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)

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  • Post published:May 20, 2025
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Leukemias are cancers of the blood forming cells that afflict both children and adults. Many drugs have been developed to treat leukemias and related diseases. These drugs are often effective…

Continue ReadingDevelopment of Highly Active Anti-Leukemia Stem Cell Therapy (HALT)
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