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Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication

  • Post author:
  • Post published:May 30, 2026
  • Post category:

Leukemia is the most frequent form of cancer in children and teenagers, but is also common in adults. Chemotherapy has vastly improved the outcome of leukemia over the past four…

Continue ReadingDual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication

Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication

  • Post author:
  • Post published:May 30, 2026
  • Post category:

Leukemia is the most frequent form of cancer in children and teenagers, but is also common in adults. Chemotherapy has vastly improved the outcome of leukemia over the past four…

Continue ReadingDual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication

Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

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  • Post published:May 30, 2026
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Cancer is the leading cause of death for individuals under 85. Relapse and metastatic disease are the leading causes of cancer related mortality. Anti-apoptotic BCL2 family member overexpression has been…

Continue ReadingPreclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy

Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells

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  • Post published:May 30, 2026
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Various cells and organs in the human body originate from a small group of primitive cells called stem cells. Human cancer cells were also recently found to arise from a…

Continue ReadingCombinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells

RNA Analysis by Biosynthetic Tagging (RABT): a tool for the identification of cell type-specific RNAs

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  • Post published:May 30, 2026
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Advancing our understanding of stem cell biology often relies on answers to the following types of questions: What are the differences in gene expression between a stem cell and the…

Continue ReadingRNA Analysis by Biosynthetic Tagging (RABT): a tool for the identification of cell type-specific RNAs

Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells

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  • Post published:May 30, 2026
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Cancer is the leading cause of death for people younger than 85. High cancer mortality rates related to resistance to therapy and malignant progression underscore the need for more sensitive…

Continue ReadingDerivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells

Stem Cells in Lung Cancer

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  • Post published:May 30, 2026
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Lung cancer is the most deadly cancer worldwide and accounts for more deaths than prostate cancer, breast cancer and colon cancer combined. Non small cell lung cancer (NSCLC) accounts for…

Continue ReadingStem Cells in Lung Cancer

Derivation and Characterization of Cancer Stem Cells from Human ES Cells

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  • Post published:May 30, 2026
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Cancer is the leading cause of death for people younger than 85 (1). High cancer mortality rates underscore the need for more sensitive diagnostic techniques as well as therapies that…

Continue ReadingDerivation and Characterization of Cancer Stem Cells from Human ES Cells

Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

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  • Post published:May 30, 2026
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Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow that is rapidly fatal within months if untreated. Even with aggressive treatment, including chemotherapy and bone marrow…

Continue ReadingDevelopment of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells

Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors

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  • Post published:May 30, 2026
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Cancer is a major cause of human death worldwide. The vast majority of cancer patients suffer from solid tumors whose growth destroys vital organs. We propose to develop novel therapeutic…

Continue ReadingTherapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors
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