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Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells

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  • Post published:May 20, 2025
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Most heart conditions leading to sudden death or impaired pumping heart functions in the young people (

Continue ReadingStudying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells

Modeling Alexander disease using patient-specific induced pluripotent stem cells

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  • Post published:May 20, 2025
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Alexander disease (AxD) is a devastating childhood disease that affects neural development and causes mental retardation, seizures and spasticity. The most common form of AxD occurs during the first two…

Continue ReadingModeling Alexander disease using patient-specific induced pluripotent stem cells

Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain

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  • Post published:May 20, 2025
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White matter is the infrastructure of the brain, providing conduits for communication between neural regions. White matter continues to mature from birth until early adulthood, particularly in regions of brain…

Continue ReadingStem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain

A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants

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  • Post published:May 20, 2025
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Successful stem cell therapy requires the replacement of diseased or dysfunctional stem cells with healthy ones. These healthy stem cells can come from either a donor or can be stem…

Continue ReadingA monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants

Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID

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  • Post published:May 20, 2025
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Artemis is a chemical in all cells in the body that is essential for the normal development of the immune system and repairing damaged DNA. Artemis deficiency (AD) causes Severe…

Continue ReadingGene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID

Generation of hepatic cell from placental stem cell for congenital metabolic disorders

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  • Post published:May 20, 2025
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Approximately 1 in 1,500 children has a congenital metabolic disorder. These inborn errors of metabolism are caused by deficiencies of different enzymes and result in accumulation of various substances inside…

Continue ReadingGeneration of hepatic cell from placental stem cell for congenital metabolic disorders

Immune-Matched Neural Stem Cell Transplantation for Pediatric Neurodegenerative Disease

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  • Post published:May 20, 2025
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Children with inherited degenerative diseases of the brain will be among the first to benefit from novel approaches based on stem cell therapy (SCT). This assertion is based on a…

Continue ReadingImmune-Matched Neural Stem Cell Transplantation for Pediatric Neurodegenerative Disease

Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease

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  • Post published:May 20, 2025
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Autophagy is the cells mechanism for breaking down and recycling proteins. Danon disease is an inherited disorder of autophagy. Patients with this disease have major abnormalities in heart and skeletal…

Continue ReadingIdentification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease

Use of human iPS cells to study spinal muscular atrophy

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  • Post published:May 20, 2025
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Spinal muscular atrophy (SMA) is one of the most common autosomal recessive disorders that cause infant mortality. SMA is caused by loss of the Survival of Motor Neuron (SMN) protein,…

Continue ReadingUse of human iPS cells to study spinal muscular atrophy

Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo

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  • Post published:May 20, 2025
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Stem cells, including human embryonic stem cells, provide extraordinary new opportunities to model human diseases and may serve as platforms for drug screening and validation. Especially with the ever-improving effective…

Continue ReadingStudying neurotransmission of normal and diseased human ES cell-derived neurons in vivo
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