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Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice.

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  • Post published:May 20, 2025
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Continue ReadingDevelopment of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice.

Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection

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  • Post published:May 20, 2025
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The AIDS virus infects and destroys cells of the immune system such that the bodies of infected individuals cannot fight infections or some cancers. If untreated HIV infection leads to…

Continue ReadingStem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection

iPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis

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  • Post published:May 20, 2025
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Hepatitis C and fatty liver disease are the two most common liver diseases in California. Individuals from different backgrounds are susceptible to these liver diseases, but they have unique genetic…

Continue ReadingiPSC-derived Hepatocytes as Platforms for Research in Viral Hepatitis and Non-alcoholic Steatohepatitis

Stem Cell Gene Therapy for HIV in AIDS Lymphoma Patients

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  • Post published:May 20, 2025
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The Human Immunodeficiency Virus (HIV) is still a major health problem. In both developed and underdeveloped nations, millions of people are infected with this virus. HIV infects cells of the…

Continue ReadingStem Cell Gene Therapy for HIV in AIDS Lymphoma Patients

Viral-host interactions affecting neural differentiation of human progenitors

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  • Post published:May 20, 2025
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Human cytomegalovirus (HCMV) is the major cause of birth defects, almost all of which are neuronal in origin. Approximately 1% of newborns are infected, and of the 13% that are…

Continue ReadingViral-host interactions affecting neural differentiation of human progenitors

Development of RNA-based approaches to stem cell gene therapy for HIV

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  • Post published:May 20, 2025
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Despite significant advances in treatment and prevention programs, HIV infection with progression to Acquired Immunodeficiency Syndrome (AIDS) is still prevalent in California. The CDC Estimates >56,000 new cases of HIV…

Continue ReadingDevelopment of RNA-based approaches to stem cell gene therapy for HIV

Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease

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  • Post published:May 20, 2025
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AIDS is a disease that currently has no cure. It arises when the human immunodeficiency virus (HIV) infects certain types of blood cells. These cells would normally be used to…

Continue ReadingHuman Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease

Genetic modification of the human genome to resist HIV-1 infection and/or disease progression

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  • Post published:May 20, 2025
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The proposed studies describe the genetic approaches utilizing human embryonic stem cells to suppress and/or eliminate the expression of the human protein CCR5. CCR5 is found on the surface of…

Continue ReadingGenetic modification of the human genome to resist HIV-1 infection and/or disease progression

GENE-MODIFIED HEMATOPOIETIC STEM/PROGENITOR CELL BASED THERAPY FOR HIV DISEASE

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  • Post published:May 20, 2025
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Continue ReadingGENE-MODIFIED HEMATOPOIETIC STEM/PROGENITOR CELL BASED THERAPY FOR HIV DISEASE

HPSC based therapy for HIV disease using RNAi to CCR5.

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  • Post published:May 20, 2025
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RNA interference is a naturally occurring means to block the function of genes in our body. We propose that RNA interference can be used to block HIV-1 infection and its…

Continue ReadingHPSC based therapy for HIV disease using RNAi to CCR5.
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