Disease Focus: Infectious Disease
HPSC based therapy for HIV disease using RNAi to CCR5.
RNA interference is a naturally occurring means to block the function of genes in our body. We propose that RNA interference can be used to block HIV-1 infection and its reproduction within the body. When RNA interference is introduced into a stem cell, its blocking activity will be present throughout the lifetime of the stem […]
ZINC FINGER NUCLEASE-BASED STEM CELL THERAPY FOR AIDS
Some years ago it was discovered that patients homozygous for a natural mutation (the Δ32 mutation) in the CCR5 gene are generally resistant to HIV infection by blocking virus entry to a cell. Building on this observation, a study published in 2009 reported a potential “cure” in an AIDS patient with leukemia after receiving a […]
Spotlight on Disease Team Awards – HIV/AIDS: Jeff Sheehy
Spotlight on HIV/AIDS: Jeff Sheehy Jeff Sheehy, spoke at the “Spotlight on Disease Team Awards: HIV/AIDS,” an educational event presented at the CIRM Governing Board meeting on April 29, 2010. Sheehy is communications director at the UCSF AIDS Research Institute and he is a patient advocate member of the CIRM Governing Board. Sheehy was introduced […]
Spotlight on Disease Team Awards – HIV/AIDS: John Zaia
Spotlight on HIV/AIDS: John Zaia John Zaia, M.D., spoke at the “Spotlight on Disease Team Awards: HIV/AIDS,” an educational event presented at the CIRM Governing Board meeting on April 29, 2010. Zaia is the chairman in department of virology and he holds the Aaron D. and Edith Miller Chair for Gene Therapy at the Beckman […]
Spotlight on Disease Team Awards – HIV/AIDS: Loring Leeds
Spotlight on HIV/AIDS: Loring Leeds Loring Leeds, spoke at the “Spotlight on Disease Team Awards: HIV/AIDS,” an educational event presented at the CIRM Governing Board meeting on April 29, 2010. Leeds is a patient advocate and was introduce by John Zaia, M.D., chairman in department of virology at the Beckman Research Institute at the […]