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MSC engineered to produce BDNF for the treatment of Huntington’s disease

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  • Post published:October 4, 2025
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A team at UC Davis plans to use bone marrow derived mesenchymal stem cells to deliver a growth factor, called BDNF, to patients' brains in order to reduce the death…

Continue ReadingMSC engineered to produce BDNF for the treatment of Huntington’s disease

RNA-directed therapy for Huntington’s disease

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  • Post published:October 4, 2025
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Research Objective We develop a novel adeno-associated viral (AAV) vector-delivered RNA-targeting therapeutic for elimination of toxic RNA causative of Huntington’s disease. Impact There are no disease-modifying therapies for Huntington’s disease.…

Continue ReadingRNA-directed therapy for Huntington’s disease

Discovery of therapeutics for Huntington’s Disease

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  • Post published:October 4, 2025
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Research Objective The objective of the proposed research is to perform 3 independent hESC-based screens to identify drug candidates for Huntington’s Disease. Impact There are currently no effective treatments for…

Continue ReadingDiscovery of therapeutics for Huntington’s Disease

hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease

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  • Post published:October 4, 2025
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Research Objective The therapeutic candidate is a human Neural Stem Cell that secretes a protein, ApiCCT1, that aids in the prevention of disease phenotypes, for application in treatment of Huntington's…

Continue ReadinghNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease

Genetic Therapy Targeting mHTT mRNA and Somatic Expansion to Treat Huntington’s Disease

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  • Post published:October 4, 2025
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Continue ReadingGenetic Therapy Targeting mHTT mRNA and Somatic Expansion to Treat Huntington’s Disease

Advanced Therapies and Stem Cells for Huntington’s disease

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  • Post published:October 4, 2025
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Continue ReadingAdvanced Therapies and Stem Cells for Huntington’s disease

HD-CARE INAUGURAL SYMPOSIUM

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  • Post published:October 4, 2025
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Continue ReadingHD-CARE INAUGURAL SYMPOSIUM

An hESC-derived hNSC Therapeutic for Huntington’s Disease

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  • Post published:October 4, 2025
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Therapeutic Candidate or Device The therapeutic candidate is a human Neural Stem Cell product to prevent or delay disease symptoms for treatment of Huntington's disease (HD). Indication Huntington’s disease, a…

Continue ReadingAn hESC-derived hNSC Therapeutic for Huntington’s Disease

A hNSC Development Candidate for Huntington’s Disease

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  • Post published:October 4, 2025
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Huntington’s disease (HD) is a devastating degenerative brain disease with at least a 1 in 10,000 prevalence that inevitably leads to death. These numbers do not fully reflect the large…

Continue ReadingA hNSC Development Candidate for Huntington’s Disease

Huntington’s Disease Team

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  • Post published:October 4, 2025
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Huntington’s disease (HD) is a devastating degenerative brain disease with a 1 in 10,000 risk of having a mutation that inevitably leads to death. These numbers do not fully reflect…

Continue ReadingHuntington’s Disease Team
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