MSC engineered to produce BDNF for the treatment of Huntington’s disease
A team at UC Davis plans to use bone marrow derived mesenchymal stem cells to deliver a growth factor, called BDNF, to patients' brains in order to reduce the death…
In neurons and beyond: how protein interactions shape the cellular response to Huntington’s Disease
Research Objective New knowledge relating to protein-protein interactions that drive vulnerability of different cell types to neurodegeneration disease mutations using Huntington's disease as a paradigm. Impact The studies will inform…
Control of OCT4 abundance and function in human stem cells
Research Objective Our work will reveal an essential pathway that establishes precise levels of the OCT4 transcription factor and protects stem cell identity despite genetic or environmental stress. Impact Our…
Frances Saldaña: Huntington’s Disease Patient Advocate
n a span of seven years, Frances Saldaña lost her three children to Huntington's disease, a devastating neurodegenerative disease that has no cure. Despite her suffering, Saldaña continues to advocate…
Huntington’s Advocates Celebrate New Stem Cell Research Funding
This two minute video captures the excitement of the Huntington's disease patient advocate and research community when the CIRM governing board approved the Disease Team II awards on July 26th,…
Judy Roberson: Patient advocates drive stem cell scientists
Judy Roberson sat down with CIRM at the World Stem Cell Summit to discuss the role patient advocates play in driving stem cell scientists and making the goals a reality.…
Alzheimer’s and Huntington’s – Using Stem Cells to Understand and Treat Disease
(Part 4 of 7) Mathew Mark Blurton-Jones, a professor at UC-Irvine's Institute for Memory Impairments and Neurological Disorders, spoke at "Synapses Firing: Connections Made", a CIRM-hosted patient advocacy event. The…