Disease Focus: Bone or Cartilage Disease


hESCs for Articular Cartilage Regeneration

Mobility is critical for human social interactions and quality of life. In the aged mobility is progressively impaired due to painful joints. The articular cartilage in the joints is damaged. The long-term goal of our research is the utilization of human embryonic stem cells (hESCs) for cartilage formation and therefore, regeneration of articular cartilage. Stem […]

Jill Helms, Stanford – CIRM Stem Cell #SciencePitch

Edward Hsiao, UCSF – CIRM Stem Cell #SciencePitch

Songtao Shi, USC – CIRM Stem Cell #SciencePitch

Produced by the University of Southern California

Healing Bones with Stem Cells at UC Davis – Intro: CIRM Spotlight on Disease

On March 21, 2012, the CIRM board governing heard from UC Davis researchers who are using bone marrow derived mesenchymal stem cells to develop new methods for repairing bone deformities and non-healing bone fractures. A clinical trial participant who has benefited from these new methods also spoke. In this video, Claire Pomeroy, vice chancellor of […]

Healing Bones with Stem Cells at UC Davis – Kent Leach: CIRM Spotlight on Disease

The current gold standard for treating non-healing bone fractures and diseases is to graft bone from a healthy part of the body. However, in many cases this method is not sufficient, such as the failed bone grafts for movie critic Roger Ebert, who lost his lower jaw from cancer. Dr. Kent Leach, associate professor of […]

Healing Bones with Stem Cells at UC Davis – Mark Lee: CIRM Spotlight on Disease

Severe bone fractures can lead to such massive bone loss that realigning and fixing the bone with implants is not enough to heal the bone. In these cases, the trauma victim is left with chronic pain and non-functioning limbs. Dr. Mark Lee, an orthopedic surgeon at the UC Davis School of Medicine, is developing new […]

Stem Cell Clinical Trial for Broken Bones – A Patient’s Story: CIRM Spotlight on Disease

For Diane Souza, working on her 23 acre ranch in Northern California is a labor of love. But an accident in 2011 left her with a broken arm that would not heal. Souza was faced with the possibility of having only one working arm. Not wanting to give up her ranch life, she entered a […]

Healing Bones with Stem Cells at UC Davis – Q&A: CIRM Spotlight on Disease

Question and answer session from the CIRM governing board’s Spotlight on Disease seminar on March 21, 2012 in Sacramento, California. The board heard from UC Davis researchers who are using bone marrow derived mesenchymal stem cells to develop new methods for repairing bone deformities and non-healing bone fractures.

Fat-Derived Stem Cells for Tissue Repair: Michael Longaker – CIRM Science Writer’s Seminar

Michael Longaker, M.D., spoke at the Scientific Writer’s Seminar, a workshop presented on September 17, 2008 at CIRM headquarters in San Francisco. Longaker has a CIRM grant to derive and analyze pluripotent disease specific stem cells that will provide a better understanding of cardiovascular and bone disease. Longaker is a Deane P. and Louise Mitchell […]