A Phase I Clinical Trial for a Lentiviral Gene Therapy Targeting the TCIRG1 Gene for Infantile Malignant Osteopetrosis (IMO)
Rocket Pharmaceuticals is conducting a clinical trial using a gene therapy for infantile malignant osteopetrosis (IMO), a rare and life-threatening disorder that develops in infancy. IMO is caused by defective bone cell…
The role of WNT and BMP signaling pathways in iPSC to iTenocyte step-wise differentiation for tendon repair
Research Objective Development-inspired differentiation will enable efficient and specific generation of tenocytes that can repair tendon injury, restore dysfunctional tissue, and prevent long term effects. Impact This study will eliminate…
Songtao Shi, USC – CIRM Stem Cell #SciencePitch
Produced by the University of Southern California
Healing Bones with Stem Cells at UC Davis – Intro: CIRM Spotlight on Disease
On March 21, 2012, the CIRM board governing heard from UC Davis researchers who are using bone marrow derived mesenchymal stem cells to develop new methods for repairing bone deformities…
Healing Bones with Stem Cells at UC Davis – Kent Leach: CIRM Spotlight on Disease
The current gold standard for treating non-healing bone fractures and diseases is to graft bone from a healthy part of the body. However, in many cases this method is not…
Healing Bones with Stem Cells at UC Davis – Mark Lee: CIRM Spotlight on Disease
Severe bone fractures can lead to such massive bone loss that realigning and fixing the bone with implants is not enough to heal the bone. In these cases, the trauma…
Stem Cell Clinical Trial for Broken Bones – A Patient’s Story: CIRM Spotlight on Disease
For Diane Souza, working on her 23 acre ranch in Northern California is a labor of love. But an accident in 2011 left her with a broken arm that would…