CIRM Funded Clinical Trials

Induction of Tolerance to Combined Kidney and Hematopoietic Progenitor Cell Transplants from HLA Haplotype Matched Living Donors

Robert Lowsky
Disease Area: 
CIRM Grant:
Award Value:
Trial Sponsor:
Stanford University
Trial Stage: 
Phase 1
Trial Status: 
Active, not recruiting
Targeted Enrollment:
15 ID:

Stanford scientists are working with kidney transplant patients to see if injecting blood stem cells and T cells (which play an important role in the immune system) from the kidney donor into the kidney recipient can enable the recipient to bypass the need for a life-long dependence on immunosuppressant drugs which have numerous negative side effects.


Open label, single arm study.


Primary: Safety. Secondary: Preliminary efficacy.